Revisiting roles of mast cells and neural cells in keloid: exploring their connection to disease activity
ConclusionsscRNA-seq analyses of AK, IK, and MS samples unveiled substantial microenvironmental heterogeneity. Such heterogeneity might be linked to disease activity. These findings suggest the potential contribution of MCs and NCs to keloid pathogenesis. Histopathological and molecular features observed in AK and IK samples provide valuable insights into the mechanisms underlying pain and pruritus in keloid lesions. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 8, 2024 Category: Allergy & Immunology Source Type: research
Keloid and Hypertrophic Scars Treatment
CONCLUSIONS: The device was found to be safe and effective, with promising results for the treatment of hypertrophic and keloid scars.LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.PMID:38453710 | DOI:10.1007/s00266-024-03869-7 (Source: Pain Physician)
Source: Pain Physician - March 7, 2024 Category: Anesthesiology Authors: Shaked Menashe Lior Heller Source Type: research
Keloid and Hypertrophic Scars Treatment
ConclusionsThe device was found to be safe and effective, with promising results for the treatment of hypertrophic and keloid scars.Level of Evidence IIThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. (Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - March 7, 2024 Category: Cosmetic Surgery Source Type: research
The detailed histopathological characteristics of ovarian fibroma compared with thecoma, granulosa cell tumor, and sclerosing stromal tumor
CONCLUSION: Ovarian fibromas can present some maybe unexpected features rather frequently, such as cystic degeneration, hyaline plaques, prominent vascularity, increased cellularity, and some mitotic activity, thus their presence should not always prompt to an alternative diagnosis.PMID:38447489 | DOI:10.1016/j.prp.2024.155236 (Source: Cell Research)
Source: Cell Research - March 6, 2024 Category: Cytology Authors: Mousa Mobarki Alexandra Papoudou-Bai Shaqraa Musawi Michel P éoc'h Georgia Karpathiou Source Type: research
The detailed histopathological characteristics of ovarian fibroma compared with thecoma, granulosa cell tumor, and sclerosing stromal tumor
CONCLUSION: Ovarian fibromas can present some maybe unexpected features rather frequently, such as cystic degeneration, hyaline plaques, prominent vascularity, increased cellularity, and some mitotic activity, thus their presence should not always prompt to an alternative diagnosis.PMID:38447489 | DOI:10.1016/j.prp.2024.155236 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - March 6, 2024 Category: Pathology Authors: Mousa Mobarki Alexandra Papoudou-Bai Shaqraa Musawi Michel P éoc'h Georgia Karpathiou Source Type: research
A Different Approach for Protruding Earlobe Correction —Modified Fish-tail Technique
ConclusionsOur method stands out for its ability to achieve both adjustable vertical height and effective lobule correction with a reduced need for skin excision. We recommend the modified fish-tail technique as an alternative technique for prominent lobule surgery.Level of Evidence IVThis journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of contents or the online Instructions to Authorswww.springer.com/00266. (Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - March 4, 2024 Category: Cosmetic Surgery Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
The Role of Positional Information in Determining Dermal Fibroblast Diversity
Matrix Biol. 2024 Feb 27:S0945-053X(24)00036-2. doi: 10.1016/j.matbio.2024.02.009. Online ahead of print.ABSTRACTThe largest mammalian organ, skin, consisting of a dermal connective tissue layer that underlies and supports the epidermis, acts as a protective barrier that excludes external pathogens and disseminates sensory signals emanating from the local microenvironment. Dermal connective tissue is comprised of a collagen-rich extracellular matrix (ECM) that is produced by connective tissue fibroblasts resident within the dermis. When wounded, a tissue repair program is induced whereby fibroblasts, in response to alterat...
Source: Matrix Biology - February 29, 2024 Category: Molecular Biology Authors: Pratyusha Chitturi Andrew Leask Source Type: research
