Fight Aging! Newsletter, May 1st 2023
In conclusion, frailty progression accelerates in males with one LTCs and females with two LTCs or more. Health providers should be aware of planning a suitable intervention once the elderly have two or more health conditions.
Plasma Transfer Lowers Epigenetic Age and Mortality in Rats
https://www.fightaging.org/archives/2023/04/plasma-transfer-lowers-epigenetic-age-and-mortality-in-rats/
Plasma transfer from young to old individuals has produced mixed results in animals and little to no benefit in humans where assessed rigorously. These studies were driven by the hypothesis that young plasma contains m...
Source: Fight Aging! - April 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cellular Senescence in Aging Skin
In one sense, the accumulation of senescent cells with age is the same story in every tissue. These cells secrete pro-inflammatory, disruptive signaling that actively degrades tissue structure and function. The targeted destruction of lingering senescent cells produces aspects of rapid rejuvenation in aged mice. In another sense, every tissue is different and senescence in that tissue likely worthy of at least some degree of distinct study, perhaps leading to optimized therapies for clearance of senescent cells on a tissue by tissue basis, for example. Here, find a review that looks at cellular senescence in the context of...
Source: Fight Aging! - April 25, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
2021 Update on Meningeal Solitary Fibrous Tumor
Meningeal Solitary Fibrous Tumor (SFT) is an uncommon tumor, accounting for less than 1% of CNS tumors. It is a fibroblastic neoplasm with a genomic inversion at the 12q13 locus, leading to NAB2-STAT6 gene fusion and surrogate nuclear STAT6 immunohistochemical expression. SFT generally affects adults in the fifth to seventh decades. It is dural-based and typically supratentorial, but 10% have a spinal location. SFT has a high propensity for recurrence and metstasis, at times occuring decades after initial diagnosis. Imaging often prompts a pre-operative assumption of meningioma as the diagnosis. Histologically, the tumor h...
Source: neuropathology blog - April 3, 2021 Category: Radiology Tags: neoplasms Source Type: blogs
Acne: Considerations for darker skin
Acne affects millions of Americans each year and impacts people of all skin tones, yet acne can pose special challenges in people with darker skin. In darker skin, one pimple or breakout can cause dark marks, scars, or even keloids (scar tissue that continues to grow larger than the original scar) that last for months to years afterward. Those affected are left searching for the secrets to treatment — or better yet, prevention. In this post we discuss how acne and similar or related conditions may be treated, and sometimes prevented, in people with darker skin.
Acne triggers release of melanin
Melanin, the same molecule ...
Source: Harvard Health Blog - March 3, 2021 Category: Consumer Health News Authors: Arianne Shadi Kourosh, MD, MPH Tags: Skin and Hair Care Source Type: blogs
Fight Aging! Newsletter, March 9th 2020
In this study, we intravenously administrated the young mitochondria into aged mice to evaluate whether energy production increase in aged tissues or age-related behaviors improved after the mitochondrial transplantation. The results showed that heterozygous mitochondrial DNA of both aged and young mouse coexisted in tissues of aged mice after mitochondrial administration, and meanwhile, ATP content in tissues increased while reactive oxygen species (ROS) level reduced. Besides, the mitotherapy significantly improved cognitive and motor performance of aged mice. Our study, at the first report in aged animals, not only prov...
Source: Fight Aging! - March 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
HIF-1 and Age-Related Impairment of Neovascularization in Regeneration
Hypoxia inducible factor 1 (HIF-1) is known to be important in skin aging, involved in the regulation of numerous processes relevant to the maintenance and structure of skin tissue. One of these is the growth of blood vessels that is required for regeneration to take place following injury. The dysfunction of HIF-1 signaling and consequent dysfunction in blood vessel regrowth is a feature of the varieties of non-healing wounds that are observed in older people. The open access paper here reviews what is known of HIF-1 in this context.
Oxygen is key to many processes of life and is involved in all stages of wound h...
Source: Fight Aging! - March 6, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The 2019 Skinnies Awards: Keloid scars in “Black Panther.”
Wakanda can ’t stop talking about the Scar-y Villain featured in the groundbreaking superhero blockbuster. Do keloids really look that way and are there treatments? Runner-up is the facial scar featured in another Os-scar Favourite. . See it all only at Skinema.com... (Source: Skinema, dermatology in the media blog)
Source: Skinema, dermatology in the media blog - February 21, 2019 Category: Dermatology Authors: Vail Reese Tags: Film Health Source Type: blogs
Let the Hand Take a Bath with Ultrasound for Foreign Bodies
Some procedures are worth doing over and over because they are easy and fun. The bonus is they can improve outcomes for patients and prevent bouncebacks, costly follow-up exams, and prolonged pain and complications. This month we discuss the use of the ultrasound (US) water bath and bedside imaging for foreign bodies (FB). If you would like to see more about using ultrasound for FBs, see our previous blog post about wine glass in the foot. (http://bit.ly/2HSQLvZ.)Bedside US is an exquisite technique that can be used to examine and explore numerous parts of the body without using radiation. This procedure uses a s...
Source: The Procedural Pause - April 30, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
The Curse of the Keloid
Each month, we try to bring you a case that is laced with unexpected care techniques. Our hope is that our procedural pearls help enhance your practice. Procedures rarely change over time, but new techniques and equipment may help you tackle new challenges. Once you have mastered simple procedures like incision and drainage and suturing and splinting, you can move on to more advanced procedures.This month we dare you to think outside the box and combine all your skills to help this weird and wild patient. We've said it before, and we'll say it again: It may not be an emergency, but it's an emergency to your patie...
Source: The Procedural Pause - February 28, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Weird and Wild: Back Piercing and Langers’ Lines
A patient presented to the emergency department with a request to remove her back ring. Yes, that's right, her back ring. We were a bit confused at first by the piercing. The stud was placed in her back with no obvious way of removal. Our original thought was to send the patient to dermatology or even plastic surgery. The piercing certainly didn't qualify for emergency surgery or removal.A 23-year-old woman with a back piercing in the left lower back. The underlying skin condition is not infectious. This is a classic example of tinea versicolor, and is not related to the piercing. It is a common fungal infectio...
Source: The Procedural Pause - January 31, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Taming the Tattoo
What do you do when something weird and wild comes into your emergency department? This month, we mean lacerations over tattoos or body piercings. Cosmetic repair of injuries involving tattoos and piercings are important to our patients. We should ensure proper wound closure while preserving the underlying body art.Tattoos and piercings are ancient practices of body modification. This form of art appreciation continues to be a popular and important cosmetic alteration for many people. Body art ranges from ear piercings ($20-30 for earlobes) to extensive tattoos that cost thousands of dollars.Many have sentimental value ...
Source: The Procedural Pause - December 1, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Sensus Healthcare ’s Technology Uses Low-Energy X-rays Directly on Cancer Cells: Interview with CEO Joe Sardano
Sensus Healthcare is a medical device company that focuses on providing non-invasive and cost-effective treatment of non-melanoma skin cancers and keloids utilizing superficial radiation technology (SRT). Their proprietary, FDA-cleared SRT technology is used to effectively and safely treat oncological and non-oncological skin conditions. The radiation is focused onto cancer cells almost exclusively, and it penetrates no more than 5mm under the surface of the skin, sparing nearby tissues.
In 2013, Sensus Healthcare received FDA clearance in the United States to treat keloids with the SRT-100 device. Earlier this summer, Chi...
Source: Medgadget - November 20, 2017 Category: Medical Devices Authors: Alice Ferng Tags: Dermatology Exclusive Oncology Source Type: blogs
Fight Aging! Newsletter, June 5th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - June 4, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
