Fight Aging! Newsletter, March 9th 2020
In this study, we intravenously administrated the young mitochondria into aged mice to evaluate whether energy production increase in aged tissues or age-related behaviors improved after the mitochondrial transplantation. The results showed that heterozygous mitochondrial DNA of both aged and young mouse coexisted in tissues of aged mice after mitochondrial administration, and meanwhile, ATP content in tissues increased while reactive oxygen species (ROS) level reduced. Besides, the mitotherapy significantly improved cognitive and motor performance of aged mice. Our study, at the first report in aged animals, not only prov...
Source: Fight Aging! - March 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

HIF-1 and Age-Related Impairment of Neovascularization in Regeneration
Hypoxia inducible factor 1 (HIF-1) is known to be important in skin aging, involved in the regulation of numerous processes relevant to the maintenance and structure of skin tissue. One of these is the growth of blood vessels that is required for regeneration to take place following injury. The dysfunction of HIF-1 signaling and consequent dysfunction in blood vessel regrowth is a feature of the varieties of non-healing wounds that are observed in older people. The open access paper here reviews what is known of HIF-1 in this context. Oxygen is key to many processes of life and is involved in all stages of wound h...
Source: Fight Aging! - March 6, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The 2019 Skinnies Awards:   Keloid scars in “Black Panther.”
Wakanda can ’t stop talking about the Scar-y Villain featured in the groundbreaking superhero blockbuster.  Do keloids really look that way and are there treatments?  Runner-up is the facial scar featured in another Os-scar Favourite. . See it all only at (Source: Skinema, dermatology in the media blog)
Source: Skinema, dermatology in the media blog - February 21, 2019 Category: Dermatology Authors: Vail Reese Tags: Film Health Source Type: blogs

Let the Hand Take a Bath with Ultrasound for Foreign Bodies
​Some procedures are worth doing over and over because they are easy and fun. The bonus is they can improve outcomes for patients and prevent bouncebacks, costly follow-up exams, and prolonged pain and complications. This month we discuss the use of the ultrasound (US) water bath and bedside imaging for foreign bodies (FB). If you would like to see more about using ultrasound for FBs, see our previous blog post about wine glass in the foot. (​Bedside US is an exquisite technique that can be used to examine and explore numerous parts of the body without using radiation. This procedure uses a simpl...
Source: The Procedural Pause - April 30, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

The Curse of the Keloid
​Each month, we try to bring you a case that is laced with unexpected care techniques. Our hope is that our procedural pearls help enhance your practice. Procedures rarely change over time, but new techniques and equipment may help you tackle new challenges. Once you have mastered simple procedures like incision and drainage and suturing and splinting, you can move on to more advanced procedures.​This month we dare you to think outside the box and combine all your skills to help this weird and wild patient. We've said it before, and we'll say it again: It may not be an emergency, but it's an emergency to your patient.A...
Source: The Procedural Pause - February 28, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Weird and Wild: Back Piercing and Langers’ Lines
​A patient presented to the emergency department with a request to remove her back ring. Yes, that's right, her back ring. We were a bit confused at first by the piercing. The stud was placed in her back with no obvious way of removal. Our original thought was to send the patient to dermatology or even plastic surgery. The piercing certainly didn't qualify for emergency surgery or removal.​​​A 23-year-old woman with a back piercing in the left lower back. The underlying skin condition is not infectious. This is a classic example of tinea versicolor, and is not related to the piercing. It is a common fungal infectio...
Source: The Procedural Pause - January 31, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Taming the Tattoo
​What do you do when something weird and wild comes into your emergency department? This month, we mean lacerations over tattoos or body piercings. Cosmetic repair of injuries involving tattoos and piercings are important to our patients. We should ensure proper wound closure while preserving the underlying body art.Tattoos and piercings are ancient practices of body modification. This form of art appreciation continues to be a popular and important cosmetic alteration for many people. Body art ranges from ear piercings ($20-30 for earlobes) to extensive tattoos that cost thousands of dollars.Many have sentimental value ...
Source: The Procedural Pause - December 1, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Sensus Healthcare ’s Technology Uses Low-Energy X-rays Directly on Cancer Cells: Interview with CEO Joe Sardano
Sensus Healthcare is a medical device company that focuses on providing non-invasive and cost-effective treatment of non-melanoma skin cancers and keloids utilizing superficial radiation technology (SRT). Their proprietary, FDA-cleared SRT technology is used to effectively and safely treat oncological and non-oncological skin conditions. The radiation is focused onto cancer cells almost exclusively, and it penetrates no more than 5mm under the surface of the skin, sparing nearby tissues. In 2013, Sensus Healthcare received FDA clearance in the United States to treat keloids with the SRT-100 device. Earlier this summer, Chi...
Source: Medgadget - November 20, 2017 Category: Medical Devices Authors: Alice Ferng Tags: Dermatology Exclusive Oncology Source Type: blogs

Fight Aging! Newsletter, June 5th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - June 4, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Modifying Macrophages to Accelerate Healing
The immune cells called macrophages play an important role in the healing of injuries. Their activities appear to be the key to examples of exceptional regeneration in mammals, for example. This may have something to do with their clearance of the transient senescent cells generated during regeneration, or may be related to other signaling processes. Researchers have in previous years shown that adjusting the behavior of macrophages can alter the pace at which wounds heal, and it is hoped that this might be a compensatory approach capable of reducing the loss of regenerative capacity that occurs with aging. Here is a recen...
Source: Fight Aging! - May 29, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Smart Scar-Care Personalized Dual Therapy Device for Hypertrophic Scars
At the The Hong Kong Polytechnic University (PolyU) engineers have developed a innovative pad for treating hypertrophic scars and keloids. Such scars have a great deal of built-up collagen inside, forcing the scar to swell and protrude from the rest of the skin. Delivering pressure onto the scar via a pad helps it to heal better. Additionally, moisturizing the wound provides its own benefit. Existing methods offer either pressure or silicone gel for moisture, but the Smart Scar-Care Pad from PolyU does both at the same time. The device has a silicone rubber exterior which consists of an array of differe...
Source: Medgadget - May 1, 2017 Category: Medical Equipment Authors: Editors Tags: Plastic Surgery Source Type: blogs

Manipulating the Wound Healing Process to Prevent Scarring
While there are some engineered mammalian lineages that can heal small wounds without scarring, further investigations of the biochemistry involved have yet to lead to a robust clinical treatment. Other lines of research are starting to look more promising, however. Here researchers demonstrate early implementations of a methodology that may prove to be the basis for a practical therapy to reduce scar tissue formation in wound healing: Fat cells called adipocytes are normally found in the skin, but they're lost when wounds heal as scars. The most common cells found in healing wounds are myofibroblasts, which were ...
Source: Fight Aging! - January 6, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Take a Cue
Tuesday - Entry 41:   I am sitting in the Sandy library and thinking about my options. Today I received the results of the MRI for my elbow. Unlike the prolapsed disks in my spine that have not healed, my elbow seems to have recovered from the car accident last Spring. Healthy joint. Untorn ligaments. Everything looks right as rain except for a large, lumpy thing on the tip of it. The bruising I had experienced seems to have subsided. I can carry groceries without pain now. I can do push-ups and ride exercise bikes. I imagine I can start taking my bike out for a ride again, something I have sorely missed doing all sum...
Source: The Splintered Mind by Douglas Cootey - November 20, 2013 Category: Mental Illness Tags: Journaling Writing Source Type: blogs

Sensus SRT-100 Now FDA Approved for Keloids
Sensus Healthcare (Boca Raton FL) received FDA approval to begin marketing its SRT-100 superficial radiotherapy system for the treatment of keloids, or scar tissue that forms over a wound whether from injury or surgical procedures. The system is used otherwise for treatment of non-melanoma skin cancers during in-office procedures.The SRT-100 utilizes superficial X-rays to deliver radiation to the surface of the skin while causing no pain and not requiring anesthesia.Read More (Source: Medgadget)
Source: Medgadget - May 31, 2013 Category: Technology Consultants Authors: Editors Tags: Dermatology Plastic Surgery Source Type: blogs

Dangers of body piercing
 Punching a hole in your  tongue, nipples, or worse your genitals, is a serious decision.  Before you decide to have a body piercing, consider the risks of infection, allergic reactions, nerve damage, teeth damage, bleeding, and  bacterial and viral infections.DANGERS OF BODY PIERCINGFashion has no boundaries. We will go to to all limits to keep up with the latest fashion.  For the past 20 years, celebrities, singers, and sport stars, all have had some body piercing.  Popular body parts are the:  eyebrows, lips, tongue, nose, ear, and even genitalia.    EAR P...
Source: Dr. Needles Medical Blogs - July 21, 2010 Category: Physicians With Health Advice Tags: DANGERS OF BODY PIERCING Source Type: blogs

Saying Goodbye to Surgery Scars
If you’re planning to have cancer surgery in the near future or recently had surgery, your thoughts undoubtedly move to how you can minimize the trauma and scarring associated with treatment and speed the healing process. Healing wounds whether from accidental injury or surgical intervention requires a delicate interplay of multiple cell types, nutritional factors, immune processes and growth factors. Proper planning and prompt attention can promote normalization in appearance. Healing -From the Inside Out Wound healing is a stepwise process involving hemostasis, inflammation, and remodeling. During hemostasis, blood...
Source: Dr. Donna, MedicineWoman - January 26, 2009 Category: Medical Scientists Authors: Dr. Donna Tags: Personal Health healing scars supplements surgery wound healing Source Type: blogs