Candida tropicalis biofilm formation and expression levels of the CTRG ALS ‐like genes in sessile cells
This study reveals that threeCTRG ALS ‐like genes ‐ except CTRG_03797 ‐ were more upregulated in biofilm cells, although with a considerable variation in expression across the strains studied and between the CTRG genes.C. tropicalis present a high biofilm capacity, and the overexpression of severalCTRG ALS ‐like genes in the sessile cells suggest a role by the course of the biofilm formation. (Source: Yeast)
Source: Yeast - November 26, 2018 Category: Molecular Biology Authors: Mar ía Ángeles Galán‐Ladero,
María Teresa Blanco‐Blanco,
María Coronada Fernández‐Calderón,
Leopoldo Lucio,
Yolanda Gutiérrez‐Martín,
María Teresa Blanco,
Ciro Pérez‐Giraldo Tags: RESEARCH ARTICLE Source Type: research
Andr é Goffeau: from proteins to genes to genomes: the Goffeaumic approach to life sciences
Yeast, Volume 0, Issue ja, -Not available-. (Source: Yeast)
Source: Yeast - November 23, 2018 Category: Molecular Biology Authors: Marc Boutry,
Henri Batoko,
Fran çois Chaumont,
Michel Ghislain,
Charles Hachez,
Pierre Morsomme Tags: SPECIAL ISSUE ARTICLE Source Type: research
3 ‐Bromopyruvate (3BP) as a Potent Anticancer Therapy in Honor and Memory of the Late Professor André Goffeau
Abstract3 ‐bromopyruvate (3BP) is a small, highly reactive molecule formed by bromination of pyruvate. In the year 2000 the antitumor properties of 3BP were discovered. Studies using animal models proved its high efficacy for anti‐cancer therapy with no apparent side effects. This was also found to be the case in a limited number of cancer patients treated with 3BP. Due to the 'Warburg effect' most tumor cells exhibit metabolic changes, e.g., increased glucose consumption and lactic acid production resulting from mitochondrial bound overexpressed hexokinase 2. Such alterations promote cell migration , immortalityvia in...
Source: Yeast - November 21, 2018 Category: Molecular Biology Authors: Young H. Ko,
Katarzyna Nied źwiecka,
Margarida Casal,
Peter L. Pedersen,
Stanisław Ułaszewski Tags: SPECIAL ISSUE ARTICLE Source Type: research
The plasma membrane H+ ‐ATPase, a simple polypeptide with a long history
AbstractThe plasma membrane H+‐ATPase of fungi and plants is a single polypeptide of fewer than 1,000 residues that extrudes protons from the cell against a large electric and concentration gradient. The minimalist structure of this nanomachine is in stark contrast to that of the large multi‐subunit FOF1 ATPase of mitochondria, which is also a proton pump, but under physiological conditions runs in the reverse direction to act as an ATP synthase. The plasma membrane H+‐ATPase is a P‐type ATPase, defined by having an obligatory phosphorylated reaction cycle intermediate, like cation pumps of animal membranes, and th...
Source: Yeast - November 16, 2018 Category: Molecular Biology Authors: Michael Palmgren,
Pierre Morsomme Tags: SPECIAL ISSUE ARTICLE Source Type: research
A genomic survey of nitrogen assimilation pathways in budding yeasts (sub ‐phylum Saccharomycotina).
This study also successfully identified yeast homologs of all six previously known eukaryotic genes involved in the biosynthesis of the molybdenum cofactor (MoCo), which is required for the activity of the nitrogen assimilation‐associated enzymes nitrate reductase and xanthine oxidoreductase. Anal ysis of 1187 upstream intergenic regions identified three novel putative regulatory motifs for the assimilation of uracil, purines and uric acid as well as a possible role for the MADS‐box transcription factor Mcm1 in the regulation of amine assimilation genes. (Source: Yeast)
Source: Yeast - November 16, 2018 Category: Molecular Biology Authors: Tomas Linder Tags: SPECIAL ISSUE Source Type: research
TORC1 ‐signalling is down‐regulated in Saccharomyces cerevisiae hsp30Δ cells by SNF1‐dependent mechanisms
AbstractHsp30 is a plasma membrane localized heat shock protein inSaccharomyces cerevisiae whose expression is induced by numerous environmental stressors. Elucidation of its mechanism of action has remained elusive primarily becausehsp30Δ cells do not show a strong phenotype. To identify cellular functions associated with Hsp30, we thus compared the transcriptome of BY4741hsp30Δ with that of its wild type counterpart. Our studies indicate down‐regulation of the target of rapamycin complex 1 (TORC1)‐dependent gene‐expression programme inhsp30Δ cells. We further show that TORC1‐signalling through its effectors (S...
Source: Yeast - November 7, 2018 Category: Molecular Biology Authors: Ajeet Singh,
Daipayan Chowdhury,
Avinash Gupta,
Ramesh Chand Meena,
Amitabha Chakrabarti Tags: RESEARCH ARTICLE Source Type: research
Issue Information
Yeast,Volume 35, Issue 11, Page 628-628, November 2018. (Source: Yeast)
Source: Yeast - November 5, 2018 Category: Molecular Biology Source Type: research
Issue Information
Yeast,Volume 35, Issue 11, Page 589-590, November 2018. (Source: Yeast)
Source: Yeast - November 5, 2018 Category: Molecular Biology Source Type: research
A fast and tuneable auxin ‐inducible degron for depletion of target proteins in budding yeast
Yeast,Volume 0, Issue ja, -Not available-. (Source: Yeast)
Source: Yeast - October 30, 2018 Category: Molecular Biology Authors: Gonzalo I. Mendoza ‐Ochoa,
J. David Barrass,
Barbara R. Terlouw,
Isabella E. Maudlin,
Susana Lucas,
Emanuela Sani,
Vahid Aslanzadeh,
Jane A.E. Reid,
Jean D. Beggs Source Type: research
The phenomenon of lipid metabolism “cut” mutants
Yeast, EarlyView. (Source: Yeast)
Source: Yeast - October 30, 2018 Category: Molecular Biology Authors: R óbert Zach,
Martin Převorovský Source Type: research
All about CDR transporters: Past, present, and future
Yeast, EarlyView. (Source: Yeast)
Source: Yeast - October 29, 2018 Category: Molecular Biology Authors: Rajendra Prasad,
Elisabetta Balzi,
Atanu Banerjee,
Nitesh Kumar Khandelwal Source Type: research
Simulated microgravity triggers characteristic morphology and stress response in Saccharomyces cerevisiae
Yeast,Volume 0, Issue ja, -Not available-. (Source: Yeast)
Source: Yeast - October 23, 2018 Category: Molecular Biology Authors: Shota Nemoto,
Shinsuke Ohnuki,
Fumiyoshi Abe,
Yoshikazu Ohya Source Type: research
Dhh1 is a Member of the SESA Network
Yeast,Volume 0, Issue ja, -Not available-. (Source: Yeast)
Source: Yeast - October 22, 2018 Category: Molecular Biology Authors: Beng ü Ergüden Source Type: research
TORC1 ‐signalling is down‐regulated in Saccharomyces cerevisiae hsp30Δ cells by SNF1 dependent mechanisms.
Yeast,Volume 0, Issue ja, -Not available-. (Source: Yeast)
Source: Yeast - October 18, 2018 Category: Molecular Biology Authors: Ajeet Singh,
Daipayan Chowdhury,
Avinash Gupta,
Ramesh Chand Meena,
Amitabha Chakrabarti Source Type: research
The Saccharomyces cerevisiae poly (A) binding protein (Pab1): Master regulator of mRNA metabolism and cell physiology
Yeast, EarlyView. (Source: Yeast)
Source: Yeast - October 17, 2018 Category: Molecular Biology Authors: Marco Brambilla,
Francesca Martani,
Stefano Bertacchi,
Ilaria Vitangeli,
Paola Branduardi Source Type: research
