The Effect of Short Duration of Electrical Stimulation on Wound Healing in Acute Wound in a Rat Model
ConclusionES application for 10-min significantly reduced inflammation, improved reepithelialization and angiogenesis when compared to shorter and longer applications. ES for 10 minutes also significantly improved wound healing when compared to the use of modern dressing alone. Therefore, it is recommended to apply ES for 10 minutes a day to improve wound healing. (Source: Wound Medicine)
Source: Wound Medicine - February 23, 2019 Category: General Medicine Source Type: research
Long-term negative pressure wound therapy decreases a risk of diabetic foot amputation assessed in the university of Texas wound classification
ConclusionsNPWT significantly decraeses risk of amputation in Texas Score. NPWT may not help in healing wounds simultaneously infected and ischeamic. Presence of ischemic wound decreases chance for successful outcome. (Source: Wound Medicine)
Source: Wound Medicine - February 23, 2019 Category: General Medicine Source Type: research
Long-term Negative Pressure Wound Therapy Decreases Diabetic Foot's Risk of Amputation Assessed in the University of Texas Wound Classification
ConclusionsNPWT significantly decraeses risk of amputation in Texas Score. NPWT may not help healing wounds simultaneously infected and ischeamic. Presence of ischemic wound decreases chance for successful outcome. (Source: Wound Medicine)
Source: Wound Medicine - February 16, 2019 Category: General Medicine Source Type: research
Wound healing characteristics of a novel wound healing ointment in an abrasive wound model: a randomised, intra-individual clinical investigation
ConclusionSuperficial cutaneous wounds treated with the novel wound healing ointment displayed a significant improvement of wound healing with an earlier onset of re-epithelization, faster wound closure and a better cosmetic outcome. Clinically relevant accelerated wound healing compared to traditional dry healing could be shown demonstrating the benefits of moist wound healing conditions also in the treatment of minor, superficial wounds (Clinical trial identification number: EUDAMED_CIV 17-04-019364). (Source: Wound Medicine)
Source: Wound Medicine - February 12, 2019 Category: General Medicine Source Type: research
Effectiveness of the sodium alginate as surgical sealant materials
Publication date: Available online 7 February 2019Source: Wound MedicineAuthor(s): Gulsan AS Kazi, Osamu YamamotoAbstractDeveloping biocompatible tissue adhesives is a highly desired goal of the tissue engineering due to adverse effects of the sutures. Sodium alginate is a natural linear polysaccharide and has biocompatibility, non-toxicity, non-immunogenicity, biodegradability, antimicrobial activity, and can be simply gelled with divalent cations and used in a number of biomedical applications. So, in this study, we use simple Na-alginate solution as surgical sealant for wound close. We prepared 0.3% (w/w) alginate hydro...
Source: Wound Medicine - February 8, 2019 Category: General Medicine Source Type: research
Wound healing models: A systematic review of animal and non-animal models
In conclusion, animal models despite their many disadvantages remain the best available alternative to study the complex cellular and molecular interactions that occur during the wound healing process in a biologically relevant environment. Multiple models are necessary to study different types of chronic wounds due to the lack of an ideal comprehensive model that is close to humans. (Source: Wound Medicine)
Source: Wound Medicine - January 1, 2019 Category: General Medicine Source Type: research
Wound Healing Models; A Systematic Review of Animal and Non-Animal Models
In conclusion, animal models despite their many disadvantages remain the best available alternative to study the complex cellular and molecular interactions that occur during the wound healing process in a biologically relevant environment. Multiple models are necessary to study different types of chronic wounds due to the lack of an ideal comprehensive model that is close to humans. (Source: Wound Medicine)
Source: Wound Medicine - December 30, 2018 Category: General Medicine Source Type: research
Wound Healing properties of Aqueous Extracts of Sargassum illicifolium: An In Vitro Assay
ConclusionsCell proliferation and migration were significantly faster in those treated with S.i-SW23 aqueous extracts when compared with the control group. Moreover, no cytotoxic effect of S.i aqueous extracts on L929 cell line were observed. This study suggests that S.i might be a potential therapeutic agent for skin wound healing by promoting fibroblast proliferation and migration. Further studies are highly warranted to identify active molecules in the extracts. Moreover, in-vivo studies would further verify wound healing therapeutic applications shown here. (Source: Wound Medicine)
Source: Wound Medicine - November 25, 2018 Category: General Medicine Source Type: research
Consensus recommendation: Indications and methods for microbiological wound diagnostics
ConclusionBeside a full understanding of all clinical symptoms and clinical experience of wound experts the correct microbiological wound investigation will be the basis for a succesfull management of infected wounds. (Source: Wound Medicine)
Source: Wound Medicine - November 6, 2018 Category: General Medicine Source Type: research
Consensus Recommendation Indications and methods for microbiological wound diagnostics
ConclusionBeside a full understanding of all clinical symptoms and clinical experience of wound experts the correct microbiological wound investigation will be the basis for a succesfull management of infected wounds. (Source: Wound Medicine)
Source: Wound Medicine - October 25, 2018 Category: General Medicine Source Type: research
Absorbable vs non absorbable sutures for wound closure. Systematic review of systematic reviews
ConclusionThis study demonstrates that absorbable sutures are not superior to non absorbable sutures in the three areas examined: surgical site infections, post operative complications and risk of wound dehiscence. However, there was significant heterogeneity between included RCTs in the systematic reviews. Further RCTs are needed to evaluate the differences between absorbable and non absorbable sutures that are reflected in size of wounds and location. (Source: Wound Medicine)
Source: Wound Medicine - October 5, 2018 Category: General Medicine Source Type: research
Occurrence and persistence of biofilms on cared chronic wounds: A large multicentric clinical study
DiscussionThis large difference from the previous studies found in the literature which report 60% of biofilms on chronic wounds could be explained by the inclusion criteria and sampling procedures. (Source: Wound Medicine)
Source: Wound Medicine - October 5, 2018 Category: General Medicine Source Type: research
Wound dressings for leg ulcers in Germany: distribution, regional variations and health care providers
ConclusionIn Germany, a high level of use of hydroactive wound dressings in leg ulcers and marked regional variations were found. (Source: Wound Medicine)
Source: Wound Medicine - September 21, 2018 Category: General Medicine Source Type: research
Disinfection of Pseudomonas aeruginosa-infected wounds in diabetic db/db mice by weakly acidic hypochlorous acid
ConclusionTwelve days of once-daily cleansing of P. aeruginosa-infected wounds on db/db diabetic mice with HOCl solution resulted in significantly decreased P. aeruginosa bioburden, albeit with a minor delay in wound repair. (Source: Wound Medicine)
Source: Wound Medicine - September 21, 2018 Category: General Medicine Source Type: research
Regenerative effect of epiregulin-loaded hydrogel
Publication date: December 2018Source: Wound Medicine, Volume 23Author(s): Mario Migliario, Filippo RenòAbstractRapid and efficient wound healing response is essential to maintain whole organism integrity and homeostasis. Such process could be influenced by a plethora of factors that when interfering with the different healing phases finally result in impaired tissue repair. Furthermore, defective healing process is often associated with chronic and difficult to heal wounds, both conditions deeply affecting patients’ quality of life.Advanced wound management solutions are the new standard in difficult to heal treatment ...
Source: Wound Medicine - September 21, 2018 Category: General Medicine Source Type: research
