In vitro investigation of antibacterial activity against fecal bacteria infecting wounds
ConclusionThis in vitro assay is easy to use, partly simulates fecal bacterial growth in vivo, and can be used to measure fecal bacterial growth inhibition. (Source: Wound Medicine)
Source: Wound Medicine - July 25, 2019 Category: General Medicine Source Type: research
Elevated wound fluid pH correlates with increased risk of wound infection
ConclusionsThe strength of the relationship between wound pH and clinical judgement or enzyme activities observed in this study is not sufficient to promote the use of elevated pH alone as an indicator for wound infection. However, the use of pH in combination with other indicators for wound infection, such as elevated neutrophil enzyme activity, warrants further research. (Source: Wound Medicine)
Source: Wound Medicine - July 25, 2019 Category: General Medicine Source Type: research
Publisher's Note
Publication date: June 2019Source: Wound Medicine, Volume 25, Issue 1Author(s): (Source: Wound Medicine)
Source: Wound Medicine - June 13, 2019 Category: General Medicine Source Type: research
Efficacy of selenium in controlling Acinetobacter baumannii associated wound infections
This study investigated the efficacy of the essential mineral, selenium (Se) in inhibiting skin-colonizing and biofilm forming abilities of A. baumannii in vitro.The effect of Se on A. baumannii adhesion and invasion of human skin keratinocytes (HEK001) was studied. Additionally, the efficacy of Se in inhibiting A. baumannii biofilm formation was determined using an in vitro collagen matrix wound model, and scanning electron microscopy (SEM) was done to visualize its potential antibiofilm effect. The effect of Se on critical A. baumannii genes for biofilm synthesis was also determined using real-time qPCR (RT-qPCR).Seleniu...
Source: Wound Medicine - June 13, 2019 Category: General Medicine Source Type: research
Healing activity of Stryphnodendron adstringens (Mart.), a Brazilian tannin-rich species: A review of the literature and a case series
ConclusionConsidering the difficulty in treating chronic or extensive wounds, barbatimão could be an effective, low-cost phytotherapy formulation with low levels of toxicity. (Source: Wound Medicine)
Source: Wound Medicine - June 8, 2019 Category: General Medicine Source Type: research
In vivo – Wound healing studies of Leptospermum scoparium honey loaded chitosan bioactive wound dressing
Publication date: September 2019Source: Wound Medicine, Volume 26, Issue 1Author(s): R. Rathinamoorthy, L. SasikalaAbstractThe research aimed to develop a bioactive wound dressing using chitosan and Leptospermum scoparium honey, which is commonly known as Manuka Honey. The wound dressing was developed using solvent- casting technique with the honey as a drug. The wound healing ability of the developed dressing was evaluated against three different wound models namely excision, incision and burn wound model in terms of wound contraction percentage and histopathological examination. The results of the study revealed that the...
Source: Wound Medicine - June 8, 2019 Category: General Medicine Source Type: research
Wound Healing Properties of Epiphyllum oxypetalum (DC.) Haw. Leaf Extract in Streptozotocin-induced Diabetic Mice by Topical Application
In conclusion, topical application of 96% ethanol extract of Epiphyllum oxypetalum leaves could accelerate the wound healing time in diabetic mice, where the best activity was shown by 20% Epiphyllum oxypetalum extract. (Source: Wound Medicine)
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research
In vivo - Wound Healing Studies of Leptospermum scoparium Honey loaded Chitosan Bioactive Wound dressing
Publication date: Available online 5 June 2019Source: Wound MedicineAuthor(s): R. Rathinamoorthy, L. SasikalaAbstractThe research aimed to develop a bioactive wound dressing using chitosan and Leptospermum scoparium honey, which is commonly known as Manuka Honey. The wound dressing was developed using solvent- casting technique with the honey as a drug. The wound healing ability of the developed dressing was evaluated against three different wound models namely excision, incision and burn wound model in terms of wound contraction percentage and histopathological examination. The results of the study revealed that the perfo...
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research
Biostimulation of venous chronic ulcers with platelet-rich plasma gel and biocompatible membranes of chitosan and alginate: a pilot study
Publication date: Available online 5 June 2019Source: Wound MedicineAuthor(s): Ana Luisa Muñoz, William Hernando Merchán, Ana Luiza Resende Pires, Ângela Maria Moraes, Lina Andrea GómezABSTRACTVenous ulcers are a common disease caused by circulatory insufficiency, having as characteristics slow healing and therefore a difficult treatment. Consequently, this disease has a high impact at personal, professional and social levels, representing large costs for both patients and healthcare system. The aim of the present pilot study was to evaluate the effectiveness of an alternative treatment for this specific type of wound,...
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research
Pilot-Study Switchable Film Dressing & NPWT: A non-interventional, non-placebo-controlled, national pilot study
Publication date: Available online 4 June 2019Source: Wound MedicineAuthor(s): Michael Schmitz (Source: Wound Medicine)
Source: Wound Medicine - June 5, 2019 Category: General Medicine Source Type: research
Topical mitomycin-C reduced number of myofibroblasts in healing anoplasty wounds in Wistar rats
Conclusions: Topical MMC reduced the myofibroblasts in the first week of healing anoplasty wounds in Wistar rats. (Source: Wound Medicine)
Source: Wound Medicine - May 11, 2019 Category: General Medicine Source Type: research
A Keratin-based biomaterial as a promising dresser for skin wound healing
Publication date: Available online 26 April 2019Source: Wound MedicineAuthor(s): Saeid Vakilian, Fatemeh Jamshidi-adegani, Sulaiman Al-Shidhani, Muhammad U. Anwar, Rashid Al-Harrasi, Nasar Al-Wahaibi, Asim Qureshi, Sausan Alyaqoobi, Issa Al-Amri, Ahmed Al-Harrasi, Sulaiman Al-HashmiAbstractKeratin-based biomaterials can be considered as the beneficial platform for designing suitable wound dressers. One of the most common natural materials that are composed of keratin and lipid is snakes shed skin. In this new study, shed skin of two different Omani snakes; Bitis arietans snake (Puff adder, “P”) and Telescopus dhara sna...
Source: Wound Medicine - April 27, 2019 Category: General Medicine Source Type: research
Topical mitomycin-c reduced myofibroblasts in healing anoplasty wounds in wistar rats
Publication date: Available online 26 April 2019Source: Wound MedicineAuthor(s): Harsali Fransiscus Lampus, Suryani As’ad, Rahmawati Minhajat, Warsinggih, Mochammad Hatta, Rina Masadah, Akhmad Makhmudi, Rosdiana Natzir, Wardihan Sinrang, Fachruddin Benyamin, Agussalim Bukhari, Nathania Wonoputri, Nita Mariana, Tommy Rubiyanto Habar (Source: Wound Medicine)
Source: Wound Medicine - April 27, 2019 Category: General Medicine Source Type: research
Evaluation of wound healing and anti-inflammatory activity of the leaves of calpurnia aurea (ait.) Benth (fabaceae) in mice
ConclusionThe results of this study demonstrated that 80% methanol extract of the leaves of Calpurnia aurea (Ait.) Benth exhibited wound healing and anti-inflammatory effects. The aqueous and ethyl acetate fractions possessed wound healing activities. (Source: Wound Medicine)
Source: Wound Medicine - March 31, 2019 Category: General Medicine Source Type: research
In vivo wound healing and antimicrobial activity of Alkanna strigose
Publication date: Available online 28 March 2019Source: Wound MedicineAuthor(s): Talal Aburjai, Reem Al-Janabi, Farah Al-Mamoori, Hanan AzzamAbstractSeveral plant preparations and extracts are used in folk medicine for treatment of topical wounds. Yet the validity of their use as well as the mechanism has not been ascertained in well-designed experimental settings. The wound healing activity of a topical hexane extract of Alkanna strigosa roots (HEASR) in excision and incision wound models in rats was evaluated. The pro-healing activity was assessed by the rate of wound contraction & wet granulation tissue weight and tensi...
Source: Wound Medicine - March 29, 2019 Category: General Medicine Source Type: research
