Evaluation of bacteriophage products against burn wound methicillin-resistant Staphylococcus aureus (MRSA) infections
ConclusionsIn conclusion the recombinant Nano phage gel is efficacy to treat and prevent MRSA burn wound infection. (Source: Wound Medicine)
Source: Wound Medicine - January 27, 2020 Category: General Medicine Source Type: research
The efficacy of platelet gel derived from umbilical cord blood on diabetic foot ulcers: A double-blind randomized clinical trial
ConclusionThe present study provides evidence that there are no significant differences in the size of wound among PG, PPP, and placebo groups. (Source: Wound Medicine)
Source: Wound Medicine - January 22, 2020 Category: General Medicine Source Type: research
Healing of Pseudomonas aeruginosa-infected wounds in diabetic db/db mice by weakly acidic hypochlorous acid cleansing and silver nanoparticle/chitin-nanofiber sheet covering
This study aimed to evaluate disinfection and wound healing by a combination of cleansing with HClO and covering with CNFS/Ag NPs daily for 3 days. Applying HClO + CNFS/Ag NPs daily for 3 days and then cleansing with just pure water and covering with CNFS alone daily for 9 days were performed for Pseudomonas aeruginosa-infected wounds in db/db diabetic mice. We found a significant enhancement of wound healing and a reduction of bacteria counts compared to the controls. Histological examination showed significantly advanced granulation tissue and capillary formations in the wounds on Day 12. These results suggest that limit...
Source: Wound Medicine - January 19, 2020 Category: General Medicine Source Type: research
The applied anatomy of human skin: a model for regeneration
Publication date: Available online 18 January 2020Source: Wound MedicineAuthor(s): Joseph M. Abdo, Nikolai A. Sopko, Stephen M. MilnerABSTRACTAutologous keratinocyte cultures and combinations of scaffolds, different cell types, solutions of macromolecules, or growth factors have contributed to the resurfacing of burns and large wounds. There are, however, significant limitations with these therapies. No tissue-engineered substitute can fully replace the split-thickness skin graft for permanent coverage of full-thickness skin loss in one step, and none contain a functional vascular plexus. Current research characterizes ski...
Source: Wound Medicine - January 19, 2020 Category: General Medicine Source Type: research
Fabrication of Pomegranate/Honey Nanofibers for Use as Antibacterial Wound Dressings
Publication date: Available online 18 January 2020Source: Wound MedicineAuthor(s): Sara S. Abou Zekry, Ahmed Abdellatif, Hassan M.E. AzzazyAbstractHoney, pomegranate peel extract and bee venom, were used in combination with polyvinyl alcohol to develop a novel nanofibrous wound dressing. Methanolic pomegranate peel extract was prepared and mixed with either Manuka honey or lyophilized multiflora honey powder together with bee venom. The formulas were tested for their antibacterial activity, cytotoxicity, and wound healing activity in an excisional wound rat model. Scanning electron microscopy showed that lyophilized honey ...
Source: Wound Medicine - January 18, 2020 Category: General Medicine Source Type: research
The efficacy of platelet gel derived from umbilical cord blood on diabetic foot ulcers: a double -blind randomized clinical trial
ConclusionThe present study provides evidence that there are no significant differences in the size of wound among PG, PPP, and placebo group. (Source: Wound Medicine)
Source: Wound Medicine - January 9, 2020 Category: General Medicine Source Type: research
Overview of 10 years of practice with CACIPLIQ20® matrix therapy as a healing agent for hard to heal wounds: efficacy, cost-effectiveness and future perspectives
ConclusionsCACIPLIQ20® can heal chronic wounds of various etiologies, sizes and ages in approximately two months, while being cost-effective. By doing so, this treatment can provide major improvement of quality of life through rapid and complete healing of chronic, hard-to-heal wounds and can reduce the economic burden of chronic wounds for health care agencies. (Source: Wound Medicine)
Source: Wound Medicine - January 9, 2020 Category: General Medicine Source Type: research
Development of in situ gels of nano calcium oxide for healing of burns
ConclusionIn situ gels of NCO were developed as a formulation for effective treatment of burns and to aid in skin regeneration. (Source: Wound Medicine)
Source: Wound Medicine - January 9, 2020 Category: General Medicine Source Type: research
Evaluation of In Vivo Wound Healing Activity of Plumeria obtusa L. (Champa) Spray in Rats
Publication date: Available online 12 November 2019Source: Wound MedicineAuthor(s): Tanay Bihani, Abhishek Bura, Nilesh MhaskeAbstractWound healing is a general repair response or process of the body immediately after the disruption of the skin integrity. However wound healing is a complex process in which body repairs itself. The aim of this research is to study the wound healing activity of ethanolic extract of Plumeria obtusa leaves and to study the efficacy of formulated 2.5%, 5% and 10% Plumeria obtusa sprays in in-vivo wound healing models. The spray was prepared in three formulations F1, F2 and F3 containing 2.5% (5...
Source: Wound Medicine - November 12, 2019 Category: General Medicine Source Type: research
Change over time of the ankle brachial index
Conclusionthese data demonstrate a change in ABI that is minimal and thus suggest that without intervening medical treatments that would change the ABI, routinely repeating this test is not warranted. (Source: Wound Medicine)
Source: Wound Medicine - October 23, 2019 Category: General Medicine Source Type: research
Topical application of lyophilized and powdered human amniotic membrane promotes diabetic ulcer healing
ConclusionsAMX ameliorated pain and extent of a chronic diabetic ulcer. The effect could be ascribed to angiogenesis and epithelium stimulation that was confirmed in in vitro. Multiple wound healing-involved proteins were detected but further studies are needed to assess their specific role. (Source: Wound Medicine)
Source: Wound Medicine - August 11, 2019 Category: General Medicine Source Type: research
Best practice recommendations for silver wound dressings: Results of an expert survey aiming to reach a consensus
Publication date: Available online 5 August 2019Source: Wound MedicineAuthor(s): J G Böttrich, H Braunwarth, J Dissemond, K C Münter, F Schümmelfeder, P WilkenZusammenfassungAkute und chronische Wunden mit lokalen Infektionszeichen oder einer kritischen Kolonisation stellen in der Versorgung eine interdisziplinäre und interprofessionelle Herausforderung in der Medizin dar. Bislang existiert keine nationale Best Practice Empfehlung für die Anwendung von Silber-Wundverbänden.Ziel dieser Arbeit war es daher, eine Sammlung von Best Practice Statements basierend auf einer strukturierten Befragung zu erstellen. Es wurden i...
Source: Wound Medicine - August 6, 2019 Category: General Medicine Source Type: research
Postoperative management of postpartum perineal tears
ConclusionsLocal therapy with Theresienol - an natural product based on natural fats and pure herbal extracts in the postoperative management of postpartum perineal tears significantly reduces the severity of clinical symptoms, and further monitoring and inclusion of new patients will show whether the risk of objective short-term and long-term complications is reduced. (Source: Wound Medicine)
Source: Wound Medicine - August 1, 2019 Category: General Medicine Source Type: research
A topical ointment formulation containing leaves extract of Aegialitis rotundifolia Roxb., accelerates excision, incision and burn wound healing in rats
ConclusionTherefore, the topical application of ARELE ointment formulations showed remarkable excision, incision and burn wound healing in Wistar rats thus showing its potential as a promising wound healing agent.Graphical abstract (Source: Wound Medicine)
Source: Wound Medicine - July 28, 2019 Category: General Medicine Source Type: research
Wound healing effect of silver nanoparticles from Tridax procumbens leaf extracts on Pangasius hypophthalmus
In this study Silver nanoparticles were synthesized using Tridax procumbens leaf extract. Nanoparticles were characterized using UV–Vis absorption spectroscopy, and Scanning Electron Microscopy (SEM). The efficacy of the synthesized silver nanoparticles on wound healing was investigated in Pangasius hypohthalmus.Biosynthesis of silver nanoparticles from the leaf extract of Tridax procumbens was found to be cost effective and time conserving. We compared the effectiveness of the synthesized silver nanoparticles from Tridax procumbens on wound healing with silver nitrate and leaf extract.Collagen deposition and fibrosis fo...
Source: Wound Medicine - July 28, 2019 Category: General Medicine Source Type: research
