Comparison of adjuvant radiation therapy alone and chemotherapy alone for low-grade gliomas without surgical resection
The combined use of chemotherapy (CT) and radiotherapy (RT) is becoming increasingly common in the treatment of surgical resected low-grade gliomas (LGGs). However, whether RT or CT is associated with improved overall survival (OS) for low-grade gliomas without surgical resection is less clear. (Source: World Neurosurgery)
Source: World Neurosurgery - September 24, 2018 Category: Neurosurgery Authors: Jing Wu, Casey Kim, Harrison X. Bai, Lei Tang, Yinyan Wang, Xuejun Li, Zishu Zhang, Giorgos Karakousis, Raymond Huang, Paul J. Zhang, Bo Xiao, Li Yang Tags: Original article Source Type: research

Random skin biopsies prior to brain biopsy for intravascular large B-cell lymphoma
To evaluate the effectiveness of random skin biopsies for intravascular large B-cell lymphoma (IVLBCL) with (IVLBCL+CNS) or without central nervous system (IVLBCL-CNS) involvement. (Source: World Neurosurgery)
Source: World Neurosurgery - September 24, 2018 Category: Neurosurgery Authors: Erika Yamada, Eiichi Ishikawa, Rei Watanabe, Hideaki Matsumura, Noriaki Sakamoto, Akiko Ishii, Akira Tamaoka, Keiichiro Hattori, Naoshi Obara, Shigeru Chiba, Kiyotaka Nakamagoe, Masahide Matsuda, Takao Tsurubuchi, Yasushi Tomidokoro, Hiroyoshi Akutsu, Ale Tags: Original article Source Type: research

Challenging Anterior Inferior Cerebellar Artery in Retrosigmoid Vestibular Schwannoma Removal
Referring to the anterior inferior cerebellar artery (AICA) traversing the cerebellopontine angle (CPA) tumor during retrosigmoid vestibular schwannoma (VS) removal as challenging AICA (c-AICA), we describe the incidence, anatomical characteristics, mechanism of development of c-AICA, and the surgical techniques used to remove VS while preserving the AICA. (Source: World Neurosurgery)
Source: World Neurosurgery - September 24, 2018 Category: Neurosurgery Authors: Iwao Yamakami, Shunsuke Kubota, Yoshinori Higuchi, Seiro Ito Tags: Original article Source Type: research

Extensive leptomeningeal intracranial and spinal metastases in a patient with a supratentorial glioblastoma multiforme, IDH-wildtype: A case report
Glioblastomas are usually characterized by diffuse, infiltrative growth and local tumor progression. Extensive leptomeningeal metastases are rarely observed. It remains unclear which GBMs are prone to this specific growth pattern/progression and standardized salvage treatment protocols are unavailable. (Source: World Neurosurgery)
Source: World Neurosurgery - September 22, 2018 Category: Neurosurgery Authors: Christoph Schwartz, Alexander Romagna, Lukas Machegger, Lukas Weiss, Florian Huemer, Gerd Fastner, Waltraud Kleindienst, Weis Serge, Richard Greil, Peter A. Winkler Tags: Case Report Source Type: research

Surgical thrombectomy combined with bilateral decompressive craniectomy in a desperate case of coma from cerebral venous sinus thrombosis: case report and literature review
Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke. Medical and neurointerventional strategies such as in situ thrombolysis are among the standard therapies. However, these techniques are insufficient when clinical deterioration arises from mass-associated effects and transtentorial herniation, whereupon decompressive hemicraniectomy may be indicated. To the best of our knowledge, the association of open surgical thrombectomy with bilateral decompressive craniectomy has not been reported to date. (Source: World Neurosurgery)
Source: World Neurosurgery - September 22, 2018 Category: Neurosurgery Authors: Fran çois Lechanoine, Kévin Janot, Denis Herbreteau, Igor Lima Maldonado, Stéphane Velut Tags: Case Report Source Type: research

Retinal alteration associated with an arachnoid cyst of the pineal region
Retinal optical coherence tomography (OCT) is a non-invasive high-resolution imaging technique which is considered a biomarker of neurodegeneration. Several intracranial lesions can induce retrograde neurodegeneration which can be assessed using OCT. The cysts of the pineal region are usually asymptomatic and most often are an incidental radiologic finding. (Source: World Neurosurgery)
Source: World Neurosurgery - September 22, 2018 Category: Neurosurgery Authors: Ana Banc, Ioan- Ștefan Florian Tags: Case Report Source Type: research

Gene Therapy for Neurological Disease: A Neurosurgical Review
Recent approval of unprecedented gene therapies have signaled the beginning of a new era in modern medicine. This rapidly changing landscape underscores the importance of neurosurgeons developing a fundamental understanding of gene therapy, as many neurological disorders are caused by derangements in gene expression. Gene therapy, the transfer of genetic material to alter endogenous gene expression or introduce exogenous genes, has emerged as a novel therapeutic approach to treat a wide range of diseases. (Source: World Neurosurgery)
Source: World Neurosurgery - September 22, 2018 Category: Neurosurgery Authors: Frederick L. Hitti, Pedro Gonzalez-Alegre, Timothy H. Lucas Tags: Original article Source Type: research

Clear Detection of Thin-Walled Regions in Unruptured Cerebral Aneurysms by Using Computational Fluid Dynamics
Thin-walled regions (TIWRs) within cerebral aneurysms have a high risk of rupture during surgical manipulation. Previous reports have demonstrated specific changes in the parameters of computational fluid dynamics (CFD) in TIWRs; however, they have not been fully evaluated. We identified and investigated a novel parameter, wall shear stress vector cycle variation (WSSVV), with user-friendly software that could predict TIWRs. (Source: World Neurosurgery)
Source: World Neurosurgery - September 22, 2018 Category: Neurosurgery Authors: Hidehito Kimura, Masaaki Taniguchi, Kosuke Hayashi, Yosuke Fujimoto, Youichi Fujita, Takashi Sasayama, Akio Tomiyama, Eiji Kohmura Tags: Original article Source Type: research

Voice quality affection as a symptom of Chiari formation
Voice alteration as a presenting symptom in cases with Chiari formation is analysed.Outcome following atlantoaxial fixation is analysed. (Source: World Neurosurgery)
Source: World Neurosurgery - September 22, 2018 Category: Neurosurgery Authors: Atul Goel, Apurva Prasad, Abhidha Shah, Sandeep Gore, Pralhad Dharurkar Tags: Original article Source Type: research

Skull base venous anatomy associated with endoscopic skull base neurosurgery: a literature review
An understanding of the anatomy and function of the skull base venous channels is fundamentally important for safe performance of endoscopic surgery for skull base lesions. This review focuses on four skull base venous channels —namely, the intercavernous sinuses, basilar plexus, osseous veins, and inferior petroclival vein—because these have been less recognized by neurosurgeons than other major venous channels such as the inferior petrosal sinus. We reviewed the literature concerning these four venous channels and di scussed their anatomy and function. (Source: World Neurosurgery)
Source: World Neurosurgery - September 21, 2018 Category: Neurosurgery Authors: Katsuhiro Mizutani, Takenori Akiyama, Kazunari Yoshida, Masahiro Toda Tags: Literature Reviews Source Type: research

A worst case scenario - an undiagnosed, ruptured AVM managed with unconventional ways
Treatment of AVMs is, nowadays, performed at specialized neurosurgical centers, which are well equipped with microscope with green filter, neurosurgical cath-lab and experienced neurosurgeons team. The patients diagnosed with AVMs at smaller hospitals should be referred to such hospitals. But what happens when a neurosurgeon has to face the unavoidable worst case scenario, i.e., emergency unplanned surgical excision of undiagnosed, ruptured AVM with large hematoma. This case report is about management of such case. (Source: World Neurosurgery)
Source: World Neurosurgery - September 21, 2018 Category: Neurosurgery Authors: Dr Ishu Bishnoi, Dr Vikram Saini, Dr Pallavi Chugh, Dr Sheikhoo Bishnoi, Dr Geetika Duggal, Dr Anamika Adib Tags: Case Report Source Type: research

Hypophyseal involvement of acute lymphoblastic leukemia
We present an unusual case of hypophyseal involvement in a boy with acute lymphoblastic leukemia via magnetic resonance (MR) imaging findings. In our case, the acute lymphoblastic leukemia of the pituitary gland was accurately distinguished from a pituitary adenoma by contrast-enhanced dynamic hypophysis MR imaging studies. (Source: World Neurosurgery)
Source: World Neurosurgery - September 21, 2018 Category: Neurosurgery Authors: Berhan Pirimoglu, Hayri Ogul, Duygu Ozkorucu-Yildirgan, Zuhal Keskin-Yildirim, Mecit Kantarci Tags: Clinical Images Source Type: research

Endovascular Treatment for Venous Sinus Stenosis in Idiopathic Intracranial Hypertension: An Observational Study of Clinical Indications, Surgical Technique, and Long-Term Outcomes
This study investigated the long-term outcomes of venous sinus stenting in a large group of patients with IIH. (Source: World Neurosurgery)
Source: World Neurosurgery - September 21, 2018 Category: Neurosurgery Authors: Lisa B.E. Shields, Christopher B. Shields, Tom L. Yao, Brian M. Plato, Yi Ping Zhang, Shervin R. Dashti Tags: Original article Source Type: research

Letter to the Editor Regarding “Endovascular Patch Embolization for Blood Blister–Like Aneurysms in Dorsal Segment of Internal Carotid Artery”
With great interest, we read the article “Endovascular Patch Embolization for Blood Blister–Like Aneurysms in Dorsal Segment of Internal Carotid Artery” by Hao et al.1 In this article, the authors describe a novel technique with stent-assisted coiling to form a patch inside the blood blister−like aneurysm (BBA) sac, as well as the dorsal wall of the parent artery. The method integrated our understanding of the pathologic features of BBA, which are extremely fragile and may involve a wider range of parent artery beside the aneurysm sac itself. (Source: World Neurosurgery)
Source: World Neurosurgery - September 20, 2018 Category: Neurosurgery Authors: Cong Wu, Changwei Zhang, Min He Tags: Letter to the Editor Source Type: research

Reliability and Agreement of Different Spine Fracture Classification Systems: Methodologic Issue
We were interested in Pishnamaz et  al's1 article in a recent issue of WORLD NEUROSURGERY. The authors' purpose was to investigate and compare the intraobserver and interobserver agreement of the Load Sharing Classification (LSC), Thoracolumbar Injury Classification System (TLICS), and AOSpine Thoracolumbar Spine Injury Classificati on System.1 Intraobserver and interobserver reliability was interpreted using the kappa statistic. On the basis of their results, the intraobserver and interobserver reliability considering the LSC total score (k = 0.26/0.22) and TLICS total score (k = 0.41, 0.23) was fair and moderate/fair,...
Source: World Neurosurgery - September 20, 2018 Category: Neurosurgery Authors: Soodeh Shahsavari, Mehdi Naderi Tags: Letter to the Editor Source Type: research