World Journal of Microbiology and Biotechnology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The impact and safety of encapsulated nanomaterials as a new alternative against carbapenem resistant bacteria. a systematic review
AbstractThe emergence of multi drug resistant bacterial infections has caused a critical problem with implication on hospitalization and mortality rates. This systematic review aims to review the combined antimicrobial effect of nanoparticles attached to the traditionally used antibiotics, to overcome the antibiotic resistance crisis. In this systematic search we focused on preclinical studies that have used animal models, to test and evaluate the effect of nanomaterials added to antibiotics against gram negative bacteria with carbapenem resistance. Where, this newly formed structure has led to significant decrease in bact...
Source: World Journal of Microbiology and Biotechnology - January 18, 2024 Category: Microbiology Source Type: research
Microbial activity of lactic acid bacteria and hydrogen producers mediated by pH and total solids during the consolidated bioprocessing of agave bagasse
This study analyzed the fermentation products in a wide range of initial pH (pHi, 5.5 –6.9) and total solids (TS%, 8–22%) to determine the activity of these two microbial groups over time (from 24 to 120 h). Agave bagasse served as the feedstock for hydrogen production via consolidated bioprocess (CBP), while the inoculum source was the indigenous mature microbiota. In the early stage of the CBP, hydrogen production from lactic acid occurred only at pHi≥ 6.0 (ρ = 0.0004) with no effect of TS%; lactic acid accumulated below this pHi value. In this stage, lactic acid production positively correlated with a first clus...
Source: World Journal of Microbiology and Biotechnology - January 16, 2024 Category: Microbiology Source Type: research
Microbial membrane transport proteins and their biotechnological applications
AbstractBecause of the hydrophobic nature of the membrane lipid bilayer, the majority of the hydrophilic solutes require special transportation mechanisms for passing through the cell membrane. Integral membrane transport proteins (MTPs), which belong to the Major Intrinsic Protein Family, facilitate the transport of these solutes across cell membranes. MTPs including aquaporins and carrier proteins are transmembrane proteins spanning across the cell membrane. The easy handling of microorganisms enabled the discovery of a remarkable number of transport proteins specific to different substances. It has been realized that th...
Source: World Journal of Microbiology and Biotechnology - January 16, 2024 Category: Microbiology Source Type: research
Identification a novel Ganoderma FIP gene from Ganoderma capense and its functional expression in Pichia pastoris
In this study, a novel fungal immunomodulatory protein gene, named as FIP-gca, was cloned fromG. capense by homologous cloning. Sequencing analysis indicated that FIP-gca was composed of 336 bp, which encoded a polypeptide of 110 amino acids. Protein sequence blasting and phylogenetic analysis showed that FIP-gca shared homology with otherGanoderma FIPs.FIP-gca was effectively expressed inPichia pastoris GS115 at an expression level of 166.8 mg/L and purified using HisTrap™ fast-flow prepack columns. The immunomodulation capacity of rFIP-gca was demonstrated by that rFIP-gca could obviously stimulate cell proliferati...
Source: World Journal of Microbiology and Biotechnology - January 16, 2024 Category: Microbiology Source Type: research
Progress in research on the biosynthesis of 1,2,4-butanetriol by engineered microbes
Abstract1,2,4-butanetriol (BT) is a polyol with unique chemical properties, which has a stereocenter and can be divided into D-BT (theS-enantiomer) and L-BT (theR-enantiomer). BT can be used for the synthesis of 1,2,4-butanetriol trinitrate, 3-hydroxytetrahydrofuran, polyurethane, and other chemicals. It is widely used in the military industry, medicine, tobacco, polymer. At present, the BT is mainly synthesized by chemical methods, which are accompanied by harsh reaction conditions, poor selectivity, many by-products, and environmental pollution. Therefore, BT biosynthesis methods with the advantages of mild reaction cond...
Source: World Journal of Microbiology and Biotechnology - January 11, 2024 Category: Microbiology Source Type: research
Recent challenges in biological cyanidation and oxidation of sulfide-based refractory gold ore
AbstractIn mining industries, biomining (comprising biooxidation and bioleaching) is implemented to extract metals from specific ores and waste streams with less environmental effect and expense. Usually, micron-sized gold particles are held in a crystal lattice of iron sulfide minerals and expensively extracted using common approaches. Researchers and industries are interested in developing recent technology and biologically sustainable methods in both pretreatment and further extraction steps for extracting this valuable metal from ores. Diverse studies in biooxidation, as a conventional pretreatment, and biocyanidation,...
Source: World Journal of Microbiology and Biotechnology - January 10, 2024 Category: Microbiology Source Type: research
Manipulation and epigenetic control of silent biosynthetic pathways in actinobacteria
AbstractMost biosynthetic gene clusters (BGCs) of Actinobacteria are either silent or expressed less than the detectable level. The non-genetic approaches including biological interactions, chemical agents, and physical stresses that can be used to awaken silenced pathways are compared in this paper. These non-genetic induction strategies often need screening approaches, including one strain many compounds (OSMAC), reporter-guided mutant selection, and high throughput elicitor screening (HiTES) have been developed. Different types of genetic manipulations applied in the induction of cryptic BGCs of Actinobacteria can be ca...
Source: World Journal of Microbiology and Biotechnology - January 9, 2024 Category: Microbiology Source Type: research
A novel Lactiplantibacillus plantarum strain: probiotic properties and optimization of the growth conditions by response surface methodology
The objective of this study is to explore the probiotic properties and optimal growth conditions ofLactiplantibacillus plantarum BG24.L. plantarum BG24 exhibited a remarkable ability to utilize lactose, and to grow under acidic conditions and in the presence of high levels of bile salts. The strain showed the highest antibacterial activity againstL. monocytogenes Scott A (zone of inhibition: 26 mm).L. plantarum BG24 was found to be resistant to 8 of the tested 19 antibiotics using the disc diffusion method.and its multiple antibiotic resistance (MAR) index was calculated as 0.421. The adhesion rate to human intestinal ep...
Source: World Journal of Microbiology and Biotechnology - January 9, 2024 Category: Microbiology Source Type: research
An oxalate decarboxylase-like cupin domain containing protein is involved in imparting acid stress tolerance in Bacillus amyloliquefaciens MBNC
We report here the structural and functional properties of an oxalate decarboxylase (OxDC)-like cupin domain-containing protein ofBacillus amyloliquefaciens MBNC and its role in imparting tolerance to acid stress conditions. Quantitative real-time PCR(qPCR) analysis revealed 32-fold and 20-fold upregulation of the target gene [(OxDC ′)cupin] under acetic acid stress and hydrochloric acid stress, respectively, indicating its association with the acid stress response. Bacterial cells with targeted inactivation of the(OxDC ′)cupin gene using the pMUTIN4 vector system showed decreased growth and survival rate in acidic pH,...
Source: World Journal of Microbiology and Biotechnology - January 8, 2024 Category: Microbiology Source Type: research
Genomic features and comparative analysis of a multidrug-resistant Acinetobacter bereziniae strain infecting an animal: a novel emerging one health pathogen?
This study also demonstrates thatA. bereziniae can spill over from anthropogenic sources into natural environments and subsequently be transmitted to non-human hosts, making this a potential One Health bacteria that require close surveillance. (Source: World Journal of Microbiology and Biotechnology)
Source: World Journal of Microbiology and Biotechnology - January 8, 2024 Category: Microbiology Source Type: research
Indigo production goes green: a review on opportunities and challenges of fermentative production
AbstractIndigo is a widely used dye in various industries, such as textile, cosmetics, and food. However, traditional methods of indigo extraction and processing are associated with environmental and economic challenges. Fermentative production of indigo using microbial strains has emerged as a promising alternative that offers sustainability and cost-effectiveness. This review article provides a critical overview of microbial diversity, metabolic pathways, fermentation strategies, and genetic engineering approaches for fermentative indigo production. The advantages and limitations of different indigo production systems an...
Source: World Journal of Microbiology and Biotechnology - January 6, 2024 Category: Microbiology Source Type: research
Fruit residues as substrates for single-cell oil production by Rhodococcus species: physiology and genomics of carbohydrate catabolism
AbstractStrains belonging toR. opacus,R. jostii,R. fascians,R. erythropolis andR. equi exhibited differential ability to grow and produce lipids from fruit residues (grape marc and apple pomace), as well as single carbohydrates, such as glucose, gluconate, fructose and sucrose. The oleaginous species,R. opacus (strains PD630 and MR22) andR. jostii RHA1, produced higher yields of biomass (5.1 –5.6 g L−1) and lipids (38 –44% of CDW) from apple juice wastes, in comparison toR. erythropolis DSM43060,R. fascians F7 andR. equi ATCC6939 (4.1 –4.3 g L−1 and less than 10% CDW of lipids). The production of cellular bio...
Source: World Journal of Microbiology and Biotechnology - January 5, 2024 Category: Microbiology Source Type: research
Human associated Archaea: a neglected microbiome worth investigating
AbstractThe majority of research in the field of human microbiota has predominantly focused on bacterial and fungal communities. Conversely, the human archaeome has received scant attention and remains poorly studied, despite its potential role in human diseases. Archaea have the capability to colonize various human body sites, including the gastrointestinal tract, skin, vagina, breast milk, colostrum, urinary tract, lungs, nasal and oral cavities. This colonization can occur through vertical transmission, facilitated by the transfer of breast milk or colostrum from mother to child, as well as through the consumption of da...
Source: World Journal of Microbiology and Biotechnology - January 4, 2024 Category: Microbiology Source Type: research
Cellulase with Bacillus velezensis improves physicochemical characteristics, microbiota and metabolites of corn germ meal during two-stage co-fermentation
In this study, we investigated the processing effect of cellulase synergized withBacillus velezensis on the nutritional value of pretreated CGM (PCGM) in two-stage solid-state fermentation (SSF). High-throughput sequencing technology was used to explore the dynamic changes in microbial diversity. The results showed that compared with four combinations ofB. velezensis + Lactiplantibacillus plantarum (PCGM-BL), cellulase + L. plantarum (PCGM-CL),control group (PCGM-CK), and cellulase + B. velezensis + L. plantarum (PCGM-BCL), the fourth combination of PCGM-BCL significantly improved the nutritional characte...
Source: World Journal of Microbiology and Biotechnology - January 3, 2024 Category: Microbiology Source Type: research
Impacts of UV radiation on Bacillus biocontrol agents and their resistance mechanisms
AbstractBacillus biocontrol agent(s) BCA(s) such asBacillus cereus, Bacillus thuringiensis andBacillus subtilis have been widely applied to control insects ’ pests of plants and pathogenic microbes, improve plant growth, and facilitate their resistance to environmental stresses. In the last decade, researchers have shown that, the application ofBacillus biocontrol agent(s) BCA(s) optimized agricultural production yield, and reduced disease risks in some crops. However, these bacteria encountered various abiotic stresses, among which ultraviolet (UV) radiation severely decrease their efficiency. Researchers have identifie...
Source: World Journal of Microbiology and Biotechnology - January 2, 2024 Category: Microbiology Source Type: research
