Veterinary Immunology and Immunopathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Development and application of a porcine specific ELISA for the quantification of soluble CD163
Publication date: Available online 25 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): J. Alex Pasternak, Daniel J. MacPhee, John C.S. HardingAbstractThe cellular marker CD163 is a type 1 transmembrane scavenger protein found either on the surface of antigen-presenting cells or in a soluble form (sCD163), released in response to inflammation. Despite an obligatory role in porcine reproductive and respiratory virus (PRRSV) infection, information on sCD163 as a biomarker of disease outcome in swine remains limited. In the present study, we developed a sandwich ELISA using an anti-bovine CD163 antibody, L...
Source: Veterinary Immunology and Immunopathology - March 27, 2019 Category: Veterinary Research Source Type: research

Procoagulant activity of bovine neutrophils incubated with conditioned media or extracellular vesicles from Histophilus somni stimulated bovine brain endothelial cells
Publication date: Available online 25 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): José J. Rivera Rivas, Charles J. CzuprynskiAbstractHistophilus somni is a Gram negative coccobacillus that causes respiratory, reproductive and central nervous system disease in cattle. The hallmark of H. somni infection is diffuse vasculitis and intravascular thrombosis that can lead to an acute central nervous system disease known as thrombotic meningoencephalitis (TME). Because neutrophils are major players in the pathophysiology of septic meningitis, we sought to determine their role in H. somni-induced fibrin c...
Source: Veterinary Immunology and Immunopathology - March 27, 2019 Category: Veterinary Research Source Type: research

Pattern of CD14, CD16, CD163 and CD172a expression on water buffalo (Bubalus bubalis) leukocytes
This study expands mAbs available to define and study the buffalo monocytes, and also extends information available on the unique features of the buffalo immune system. (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 27, 2019 Category: Veterinary Research Source Type: research

Skin immune response of rainbow trout (Oncorhynchus mykiss) experimentally exposed to the disease Red Mark Syndrome
Publication date: Available online 23 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Louise von Gersdorff Jørgensen, Jacob Günther Schmidt, Defang Chen, Per Walter Kania, Kurt Buchmann, Niels Jørgen OlesenAbstractRed Mark Syndrome (RMS) is a skin disease reported from farmed rainbow trout. Since the turn of the millennium it has been spreading through Europe. RMS is probably a bacterial disease caused by a Midichloria-like organism (MLO). It is non-lethal and causes little obvious changes in appetite or behavior but results in red hyperaemic skin lesions, which may lead to economic losses due to d...
Source: Veterinary Immunology and Immunopathology - March 24, 2019 Category: Veterinary Research Source Type: research

Avian pathogenic Escherichia coli infection of a chicken lung epithelial cell line
Publication date: Available online 19 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Noëlle Mol, Lianci Peng, Evelyne Esnault, Pascale Quéré, Henk P. Haagsman, Edwin J.A. VeldhuizenABSTRACTVirulent strains of Escherichia coli (Avian Pathogenic E. Coli: APEC) can cause initial infection of the respiratory tract in chickens potentially leading to systemic infection called colibacillosis, which remains a major cause of economic losses in the poultry industry. The role of epithelial lung cells as first targets of APEC and in initiating the innate immune response is unclear and was investigated in this...
Source: Veterinary Immunology and Immunopathology - March 21, 2019 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: March 2019Source: Veterinary Immunology and Immunopathology, Volume 209Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 16, 2019 Category: Veterinary Research Source Type: research

Development and characterization of a canine-specific anti-CD94 (KLRD-1) monoclonal antibody
Publication date: Available online 14 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Scott S. Graves, Boglarka Gyurkocza, Diane M. Stone, Maura H. Parker, Kraig Abrams, Christoph Jochum, Susanna Gallo, Marium Saad, Melissa M. Johnson, Steven L. Rosinski, Rainer StorbABSTRACTNatural killer (NK) cells are non-T, non-B lymphocytes are part of the innate immune system and function without prior activation. The human NK cell surface determinant, CD94, plays a critical role in regulation of NK cell activity as a heterodimer with NKG2 subclasses. Canine NK cells are not as well defined as the human and muri...
Source: Veterinary Immunology and Immunopathology - March 15, 2019 Category: Veterinary Research Source Type: research

Flow-cytometric analysis of circulating leukocyte populations in turkeys: establishment of a whole blood analysis approach and investigations on possible influencing factors
In this study we established a whole blood based flow cytometric analysis method for turkeys. This method was used to determine baseline values depending on the age of the birds as well as under consideration of variations between trials and animal room effects. During three trials whole blood samples of B.U.T. 6 female turkeys were collected to analyze different leukocyte concentrations (cells/µl whole blood). In the first trial one group and in the second and third trial two groups with 22 birds/group were housed. Blood samples were collected at days one, 23, 43, 60, and 88 post hatch and concentrations of monocytes, MH...
Source: Veterinary Immunology and Immunopathology - March 15, 2019 Category: Veterinary Research Source Type: research

Stocking density induces differential expression of immune-related genes in skeletal muscle and head kidney of fine flounder (Paralichthys adspersus)
Publication date: Available online 11 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Cristián A. Valenzuela, Sebastián Escobar-Aguirre, Rodrigo Zuloaga, Tamara Vera-Tobar, Luis Mercado, Björn Thrandur Björnsson, Juan A. Valdés, Alfredo MolinaAbstractImmunity can be modulated by different internal and external factors, being stress one of the most important. However, the stress effects on the immunocompetence of the skeletal muscle has not been studied in detail in earlier vertebrates. Here, we examine the effect of chronic (4 and 7 weeks) crowding stress on the immunocompetence of skeletal muscl...
Source: Veterinary Immunology and Immunopathology - March 12, 2019 Category: Veterinary Research Source Type: research

Correlation between toll-like receptor 4 and nucleotide-binding oligomerization domain 2 (NOD2) and pathological severity in dogs with chronic gastrointestinal diseases
We examined the expression levels of TLR4, NOD2, and TNF-α in the stomach, duodenum, ileum, colon, and rectum obtained from 21 dogs with chronic gastrointestinal disease, including inflammatory bowel disease, high-grade lymphoma, food responsive enteropathy, chronic pancreatitis, low-grade lymphoma, inflammatory colorectal polyp, and chronic colitis. Next, we demonstrated whether there is good correlation between the expression levels of TLR4, NOD2, and TNF-α and the histopathological analysis of each sample. We found that the level of TLR4 expression in the ileum of dogs with chronic gastrointestinal disease was positiv...
Source: Veterinary Immunology and Immunopathology - March 10, 2019 Category: Veterinary Research Source Type: research

The effect of age on foal monocyte-derived dendritic cell (MoDC) maturation and function after exposure to killed bacteria
Publication date: Available online 9 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Brina S. Lopez, David J. Hurley, Shyla Giancola, Steeve Giguère, M. Julia. B. Felippe, Kelsey A. HartAbstractNeonatal foals are uniquely susceptible to certain infections early in life. Dendritic cells (DCs) are vital in the transition between the innate and adaptive immune response to infection, but DC biology in foals is not fully characterized. Monocyte-derived DCs represent a suitable in vitro model similar to DCs that differentiate from monocytes recruited from circulation. We hypothesized that foal monocyte-der...
Source: Veterinary Immunology and Immunopathology - March 10, 2019 Category: Veterinary Research Source Type: research

Heat stress, Eimeria spp. and C. perfringens infections alone or in combination modify gut Th1/Th2 cytokine balance and avian necrotic enteritis pathogenesis
This study analyzes the effects of heat stress on Th1/Th2 cytokine balance, pathological features, and Toll-like receptor expression in the small intestine of broiler chickens infected with Clostridium perfringens type A in the presence or absence of Eimeria spp. co-infection. This co-infection model was experimentally used because it reproduces the findings commonly observed in the field during avian NE. For this purpose, broiler chickens infected with C. perfringens and/or Eimeria spp. were reared in isolator chambers subjected or not to heat stress intermittently. It was observed that heat stress directs the expression ...
Source: Veterinary Immunology and Immunopathology - March 5, 2019 Category: Veterinary Research Source Type: research

Modulation of TNF-α, IL-1Ra and IFN-γ in equine whole blood culture by glucocorticoids
Publication date: Available online 4 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Simon Rütten, Wieland Schrödl, Getu AbrahamAbstractGlucocorticoids are important drugs in the treatment of many inflammatory, autoimmune and allergic diseases in humans and animals. We investigated the effects of hydrocortisone and dexamethasone on TNF-α, IL-1Ra and INF-γ release in stimulated whole blood cell culture from healthy horses. Whole blood cell cultures proved to be useful for the characterization of the anti-inflammatory properties of new drugs.Diluted equine whole blood was exposed to lipopolysacchari...
Source: Veterinary Immunology and Immunopathology - March 5, 2019 Category: Veterinary Research Source Type: research

Intestinal colonization and acute immune response in commercial turkeys following inoculation with Campylobacter jejuni constructs encoding antibiotic-resistance markers
Publication date: Available online 1 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Matthew J. Sylte, Timothy A. Johnson, Ella L. Meyer, Matt H. Inbody, Julian Trachsel, Torey Looft, Leonardo Susta, Zuowei Wu, Qijing ZhangAbstractConsumption of contaminated poultry products is one of the main sources of human campylobacteriosis, of which Campylobacter jejuni subsp. jejuni (C. jejuni) is responsible for approximately 90% of the cases. At slaughter, the ceca of commercial chickens and turkeys are the main anatomical site where C. jejuni asymptomatically colonizes. We have previously colonized commercia...
Source: Veterinary Immunology and Immunopathology - March 5, 2019 Category: Veterinary Research Source Type: research

Mucosal immunization with polymeric antigen BLSOmp31 using alternative delivery systems against Brucella ovis in rams
Publication date: Available online 2 March 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Alejandra Graciela Díaz, Daniela Alejandra Quinteros, Fernando Alberto Paolicchi, Mariana Alejandra Rivero, Santiago Daniel Palma, Romina Paola Pardo, María Clausse, Vanesa Zylberman, Fernando Alberto Goldbaum, Silvia Marcela EsteinAbstractSubcellular vaccines against ovine contagious epididymitis due Brucella ovis can solve some shortcomings associated with the use of Brucella melitensis Rev 1. We have demonstrated that the parenteral immunization with polymeric antigen BLSOmp31 emulsified in oil adjuvant conferred...
Source: Veterinary Immunology and Immunopathology - March 5, 2019 Category: Veterinary Research Source Type: research