Veterinary Immunology and Immunopathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Immunological Responses and Evaluation of the Protection in Dairy Cows Vaccinated with Staphylococcal Surface Proteins
The objective of this study was to evaluate the immune responses and protection in dairy cows vaccinated with S. aureus surface proteins (SASP) or S. chromogenes surface proteins (SCSP). We divided eighteen Holstein dairy cows randomly into three groups of 6 animals each. We vaccinated group 1 and 2 animals with SASP and SCSP with Emulsigen-D adjuvant, respectively. We injected control (group 3) animals with PBS (pH 7.2) in Emulsigen®-D. We vaccinated animals three times at 28 and 14 days before drying off, and at dry off. Two weeks after the third vaccination, we challenged each animal by dipping all teats in S. aureus c...
Source: Veterinary Immunology and Immunopathology - July 6, 2019 Category: Veterinary Research Source Type: research

Tumor microenvironment and stroma in intestinal adenocarcinomas and associated metastases in Atlantic salmon broodfish (Salmo salar)
Publication date: Available online 4 July 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Håvard Bjørgen, Hege Hellberg, Oskar Mongstad Løken, Gjermund Gunnes, Erling Olaf Koppang, Ole Bendik DaleAbstractAnimal models are invaluable tools in cancer research. In this context, salmon is a promising candidate. Intestinal adenocarcinoma with metastases may be induced as a consequence of a plant-based diet triggering the inflammation – dysplasia- carcinogenesis pathway. Here, we investigate the stroma and the presence and nature of immune cells in such tumors by staining for mast cells, immunohistochemistry...
Source: Veterinary Immunology and Immunopathology - July 6, 2019 Category: Veterinary Research Source Type: research

Elimination of erroneous results related to bovine mononuclear cell immunophenotyping by antibodies binding to Fc receptors
Publication date: Available online 2 July 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Cintia Hiromi Okino, Rodrigo Giglioti, César Cristiano Bassetto, Pamella Cristini Silva, Henrique Nunes de Oliveira, Márcia Cristina de Sena OliveiraAbstractBlocking immunoglobulin G (IgG) binding receptors on leukocytes is an established and highly recommended preventive procedure for immunological assays. Failing to prevent such nonspecific binding can lead to erroneous results. Several studies testing different blocking reagents have been performed in murine or human cells, however, there are no specific studies o...
Source: Veterinary Immunology and Immunopathology - July 2, 2019 Category: Veterinary Research Source Type: research

Felis catus papillomavirus type 2 virus-like particle vaccine is safe and immunogenic but does not reduce FcaPV-2 viral loads in adult cats
Publication date: Available online 28 June 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Neroli A. Thomson, Laryssa Howe, Karin Weidgraaf, David G. Thomas, Vivienne Young, Vernon K. Ward, John S. MundayAbstractFelis catus papillomavirus type 2 (FcaPV-2) commonly infects the skin of domestic cats and has been associated with the development of skin cancer. In the present study, a FcaPV-2 virus-like particle (VLP) vaccine was produced and assessed for vaccine safety, immunogenicity, and impact on FcaPV-2 viral load. This is the first report of the use of a papillomavirus VLP vaccine in domestic cats. The Fc...
Source: Veterinary Immunology and Immunopathology - June 29, 2019 Category: Veterinary Research Source Type: research

Corrigendum to “A single, low dose oral antigen exposure in newborn piglets primes mucosal immunity if administered with CpG oligodeoxynucleotides and polyphosphazene adjuvants” [Vet. Immunol. Immunopathol. 161 (2014) 211–221]
Publication date: Available online 27 June 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): J. Alex Pasternak, Siew Hon Ng, Heather L. Wilson (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 27, 2019 Category: Veterinary Research Source Type: research

Effect of progesterone on the vaccination and immune response against Chlamydia abortus in sheep
Publication date: Available online 27 June 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): A. Murcia-Belmonte, D. Álvarez, N. Ortega, J.A. Navarro, E. Gómez-Lucía, A.J. Buendía, J. Sánchez, L. del Río, J. Salinas, M.R. CaroAbstractChlamydia abortus produces ovine enzootic abortion (OEA). Symptoms are not observed until the organism colonises the placenta, eventually causing abortion. Infected animals become carriers and will shed the organism in the following oestruses. This process suggests that sex hormones might play an important role in the physiopathology of OEA, affecting the success of chlamydi...
Source: Veterinary Immunology and Immunopathology - June 27, 2019 Category: Veterinary Research Source Type: research

Protec™ improves innate immune response and specific antibody response against Lactococcus garvieae in rainbow trout (Oncorhynchus mykiss)
Publication date: July 2019Source: Veterinary Immunology and Immunopathology, Volume 213Author(s): Chiara Bulfon, Valentina Pacorig, Massimo Sarti, Umberto Luzzana, Marco Galeotti, Donatella VolpattiAbstractProtec™ is a commercial aquafeed (Skretting Italia) containing a combination of glucans, vitamin C, vitamin E and zinc (immune support pack). No research information concerning its capability to improve fish immune response is available, so in this study the potential immunomodulatory effects of Protec™ were investigated in rainbow trout (Oncorhynchus mykiss). Head kidney (HK) leukocytes from adult fish (100 g, n�...
Source: Veterinary Immunology and Immunopathology - June 27, 2019 Category: Veterinary Research Source Type: research

Early IgG2 in calves experimentally infected with Mycobacterium avium subsp. paratuberculosis
In this study, an experimental Map-infection model of calves was used to improve the knowledge of early antibody response and to evaluate different in-house ELISAs in the detection of subclinical paratuberculosis. Calves were challenged with Map strain IS900-RFLPA (n = 3) or Map strain IS900-RFLPC (n = 2) (Argentinean isolated strains) or mock infected (n = 3), and their specific humoral response was evaluated. The diagnostic ELISA (IgG against Map protoplasmic antigen; PPA) could not detect the infection throughout the experimental period (180 days post-infection; dpi), whereas the IgG2/PPA-ELISA was able to i...
Source: Veterinary Immunology and Immunopathology - June 26, 2019 Category: Veterinary Research Source Type: research

ProtecTM improves innate immune response and specific antibody response against Lactococcus garvieae in rainbow trout (Oncorhynchus mykiss)
Publication date: Available online 20 June 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Chiara Bulfon, Valentina Pacorig, Massimo Sarti, Umberto Luzzana, Marco Galeotti, Donatella VolpattiAbstractProtecTM is a commercial aquafeed (Skretting) containing a combination of glucans, vitamin C, vitamin E and zinc (immune support pack). No research information concerning its capability to improve fish immune response is available, so in this study the potential immunomodulatory effects of ProtecTM were investigated in rainbow trout (Oncorhynchus mykiss). Head kidney (HK) leukocytes from adult fish (100 g, n�...
Source: Veterinary Immunology and Immunopathology - June 21, 2019 Category: Veterinary Research Source Type: research

RNA-seq analysis of viral gene expression in the skin of Marek’s disease virus infected chickens
Publication date: Available online 18 June 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Lakshmi Sunkaraa, Syed Mudasir Ahmad, Mohammad HeidariAbstractMarek’s disease virus (MDV), a highly cell-associated oncogenic avian α-herpesvirus, is the causative agent of malignant transformation of T cells in domestic chickens. The latently infected CD4+CD8- T cells carry the virus through the blood stream and establish lymphomas in the skin, visceral organs and peripheral nerves. The feather follicle epithelium (FFE) is the only anatomical site where fully infectious enveloped virions are produced and eventuall...
Source: Veterinary Immunology and Immunopathology - June 18, 2019 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: June 2019Source: Veterinary Immunology and Immunopathology, Volume 212Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 16, 2019 Category: Veterinary Research Source Type: research

Changes in the intestinal mucosal proteome of turkeys (Meleagris gallopavo) infected with haemorrhagic enteritis virus
Publication date: Available online 7 June 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Andreia Tomás Marques, Sandra I. Anjo, Mangesh Bhide, Ana Varela Coelho, Bruno Manadas, Cristina Lecchi, Guido Grilli, Fabrizio CecilianiAbstractHaemorrhagic enteritis (HE) is a viral disease affecting intestinal integrity and barrier function in turkey (Meleagris gallopavo) and resulting in a significant economic loss. Sequential Windowed Acquisition of All Theoretical Fragment Ion Mass Spectra (SWATH-MS) was applied to identify crucial proteins involved in HE infection. A total of 938 proteins were identified and us...
Source: Veterinary Immunology and Immunopathology - June 8, 2019 Category: Veterinary Research Source Type: research

Food allergen-specific sublingual immunotherapy modulates peripheral T cell responses of dogs with adverse food reactions
Publication date: Available online 29 May 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Elisa Maina, Bert Devriendt, Eric CoxAbstractFood allergen-specific sublingual immunotherapy (FA-SLIT) is a novel, safe and effective approach in dogs with adverse food reactions (AFR) to reduce their clinical symptoms. However, little is known about the specific immune components which mediate this reduction in clinical symptoms. In humans, regulatory T cells seem to play an important role in this desensitisation process. Here, we investigated changes in peripheral T cell responses of dogs with AFR upon FA-SLIT. Five ...
Source: Veterinary Immunology and Immunopathology - May 30, 2019 Category: Veterinary Research Source Type: research

The detection of house dust mite Dermatophagoides farinae, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic dermatitis in Malaysia
Publication date: Available online 22 May 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Wei Yee Chan, Gayathri Thevi Selvarajah, Mohd Mokrish Md. Ajat, Rieko Suzuki, Toshihiro TsukuiAbstractCanine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the p...
Source: Veterinary Immunology and Immunopathology - May 24, 2019 Category: Veterinary Research Source Type: research

Differential expression of type I interferon mRNA and protein levels induced by virulent Marek’s disease virus infection in chickens
In conclusion, our study demonstrated that MDV mostly inhibited the expression of type I IFNs in infected hosts, which may be associated to its pathogenesis. (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 16, 2019 Category: Veterinary Research Source Type: research