Turkish Journal of Medical Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Melanocytic tumors with spitzoid morphology: correlation of clinicopathologic features and FISH analysis
This study is a multicentric retrospective study including three centers, İstanbul University-Cerrahpaşa, Cerrahpaşa School of Medicine, Department of Pathology, Acıbadem University, School of Medicine, Department of Pathology and ETA Pathology Laboratory. The pathology reports in archives of these three centers between 2015 and 2017 have been reviewed for cases diagnosed as atypical Spitz tumor or melanoma with Spitzoid features. These cases were selected for the study. We analyzed 39 cases of atypical Spitz tumor (AST), 10 cases of melanomas with spitzoid features for clinicopathological data and chromosomal alterati...
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Deniz Ünlüer Kapişkay Övgü Aydin Ülgen Ümit İnce C üyan Demirkesen Source Type: research

Survival outcomes of patients with oligometastatic non-small cell lung cancer who were treated with radical therapy: a multicenter analysis
In this study, we aimed to determine the efficacy of radical treatment options for patients with oligometastatic NSCLC.METHODS: This retrospective trial included totally 134 patients with oligometastatic NSCLC. The presence of oncodriver mutation, tumor stages and nodal status, the number of metastases and involved metastatic site, treatment of primary tumor and oligometastasis, response rate, overall survival (OS) and progression-free survival (PFS) were evaluated.RESULTS: Of 134 patients 66.4% were defined as adenocarcinoma, 26.1% were squamous cell carcinoma and 7.5% of patients were in other histology. Based on the tre...
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Özgür Açikgöz Ahmet Bilici Deniz Tataro ğlu Özyükseler Sabin G öktaş Aydin Fatih Sel çukbiricik Rashad Rzazade Ömer Fatih Ölmez Hale Ba şak Çağlar Source Type: research

Retrospective analysis of children diagnosed with Kawasaki disease
DISCUSSION: In our study, serum CRP levels, WBC count, and neutrophil count were higher in patients with coronary artery abnormalities, in agreement with the previous studies. In the light of our results, we consider that the most important determining factor for the development of coronary artery aneurysm is the time of intravenous immunoglobulin (IVIG) administration.PMID:38031949 | PMC:PMC10760559 | DOI:10.55730/1300-0144.5662 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Fatih Varol Reyhan Dedeo ğlu Aziz Kili ç Murat Tu ğberk Bakar Amra Adrovic Sezgin Şahin Mehmet Yildiz Kenan Barut Halit Çam Özgür Kasapçopur Source Type: research

Emergency ultrasound of respiratory muscles: a promising tool for determining the outcomes of COPD exacerbations
DISCUSSION: Diaphragmatic excursion, diaphragmatic end-expiratory thickness, and right and left intercostal muscle thicknesses vary in the prognosis of subjects presenting with COPD exacerbation.PMID:38031950 | PMC:PMC10760574 | DOI:10.55730/1300-0144.5664 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Din çer Yegin Alten Oskay T ülay Oskay Selcan Enver Din ç Hande Şenol Mert Özen Vefa Çakmak Murat Seyit Atakan Yilmaz İbrahim Türkçüer Source Type: research

The role of curcumin on apoptosis and NLRP3 inflammasome-dependent pyroptosis on colorectal cancer in vitro
DISCUSSION: Our results reveal that while curcumin effectively induces apoptosis, its effects on NLRP3-inflammasome mediated pyroptosis vary. Our results underline the need for further research focusing on the other inflammasome complexes to confirm the differential effects of curcumin on CRC.PMID:38031951 | PMC:PMC10760590 | DOI:10.55730/1300-0144.5652 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Zeynep Dal Ba şak Aru Source Type: research

Is the Pediatric Eosinophilic Esophagitis Symptom Score v2.0 reliable for telemedicine?
DISCUSSION: Unsynchronized telesurvey use of PEESS v2.0 is unreliable both for children and parents. We suggest testing the reliability of chosen telemedicine methods before using them in clinical and research practice.PMID:38031952 | PMC:PMC10760582 | DOI:10.55730/1300-0144.5649 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Sinem Polat Terece Dilek Yapar Hacer İlbilge Ertoy Karagöl Gizem K öken Demet Teker D üztaş Ödül Eğritaş Sinan Sari Buket Dalgi ç Arzu Bakirta ş Source Type: research

The impact of smoking on response to tumor necrosis factor- α inhibitor treatment in patients with ankylosing spondylitis
This study suggested that smoking was associated with poorer patient-reported outcomes in biologic naïve AS patients initiating their first TNFi treatment, but it had no impact on the TNFi treatment response and retention rate.PMID:38031953 | PMC:PMC10760557 | DOI:10.55730/1300-0144.5661 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Handan Yarkan Tu ğsal G ökçe Kenar Artin Ger çek Can Sedat Çapar Berrin Zengin Servet Akar H üseyin Ediz Dalkiliç Abdurrahman Soner Şenel S üleyman Serdar Koca Berna G öker Ayten Yazici G üzide Nevsun İnanç H ülya Ellidokuz Nurullah Akko ç Source Type: research

Initial alpha-1 antitrypsin screening in Turkish patients with chronic obstructive pulmonary disease
DISCUSSION: In patients with emphysema and normal serum AAT levels, genetic analyses may reveal relevant heterozygous mutations, which are commonly ignored. Most clinicians focus on lower lobe emphysema. Evaluations of such patients might reveal AAT mutations that are presently overlooked because they are not considered to influence COPD status.PMID:38031954 | PMC:PMC10760586 | DOI:10.55730/1300-0144.5665 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Seda Tural Önür Source Type: research

Evaluation of local and systemic side effects of Turkovac vaccine in adults
DISCUSSION: Our study revealed that Turkovac is a generally well-tolerated vaccine and had no side effects. More studies are required to evaluate Turkovac's side effects in other populations.PMID:38031955 | PMC:PMC10760581 | DOI:10.55730/1300-0144.5657 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: B ülent Nuri Kalayci Do ğu Karahan Source Type: research

Is cancer risk reduced in multiple sclerosis? Results from a tertiary referral center
DISCUSSION: There was no statistically significant difference in age, gender, tobacco smoking, and BMI between the groups after propensity score matching. The odds of having cancer were lower in our MS patients compared to the controls. The autoimmune changes responsible for the pathogenesis of MS may be responsible for the decrease in cancer risk.PMID:38031938 | PMC:PMC10760532 | DOI:10.55730/1300-0144.5660 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Yasemin Bahar Egemen Yildiz Abdul Rasheed Bahar Rana Karabudak Source Type: research

The importance of skin prick test in differentiating cat sensitivities and allergies in children
DISCUSSION: The present study is the first to report the frequency and clinical findings of cat sensitizations and allergies in Turkish children. For effective treatment, cat allergy must be diagnosed. In this regard, the use of a practical, readily accessible 5.5 mm cut-off point on the SPT may be helpful.PMID:38031939 | PMC:PMC10760561 | DOI:10.55730/1300-0144.5650 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Mehmet Şirin Kaya Özge Atay İdil Akay Haci İlke Taşkirdi Selime Özen Bölük Figen Çelebi Çelik Özgen Soyöz Canan Şule Ünsal Karkiner Demet Can Source Type: research

Effects of thymoquinone and memantine alone and in combination on memory and hippocampal morphology in rats with streptozotocin-induced Alzheimer's disease
DISCUSSION: We found that TQ alone and in combination with MEM showed ameliorative effects on memory and hippocampal morphology. TQ may offer a promising treatment strategy for AD.PMID:38031940 | PMC:PMC10760553 | DOI:10.55730/1300-0144.5653 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Şeyma Özsoy Ziya Çakir Elif Ak çay Fikret Gevrek Source Type: research

Nutritional risks in children with food allergy
In conclusion, nutritional risk assessment of children with FA requires a comprehensive, detailed, and multidisciplinary approach.PMID:38031941 | PMC:PMC10765559 | DOI:10.55730/1300-0144.5648 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Zeynep Parlak Deniz İlgün Gürel Özge Uysal Soyer B ülent Enis Şekerel Ümit Murat Şahiner Source Type: research

CRM1 expression: association with high prognostic value in laryngeal cancer
DISCUSSION: Consequently, CRM1 plays an important role in laryngeal cancer and may serve as an indicator and prognostic factor for poor overall survival in laryngeal cancer patients.PMID:38031942 | PMC:PMC10760544 | DOI:10.55730/1300-0144.5655 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Talih Özdaş Sibel Özdaş İpek Canatar Erdal Co şgun Elif Burcu Şenyurt Orhan G örgülü Source Type: research

In vitro hepatotoxicity evaluation of methotrexate-loaded niosome formulation: fabrication, characterization and cell culture studies
DISCUSSION: These results demonstrated that niosomal drug delivery systems could be a new potential formulation for minimizing MTX-related hepatotoxicity.PMID:38031943 | PMC:PMC10760534 | DOI:10.55730/1300-0144.5651 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 30, 2023 Category: General Medicine Authors: Ahmet Do ğan Ergin Çağatay Oltulu Nebiye Pelin T ürker G ülen Melike Demirbolat Source Type: research