Correction to TINS 1828 Contributions by metaplasticity to solving the Catastrophic Forgetting Problem: (Trends in Neurosciences, 45:9 p:656-666, 2022)
Trends Neurosci. 2023 Aug 18:S0166-2236(23)00173-X. doi: 10.1016/j.tins.2023.07.008. Online ahead of print.NO ABSTRACTPMID:37599184 | DOI:10.1016/j.tins.2023.07.008 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 20, 2023 Category: Neuroscience Authors: Peter Jedlicka Matus Tomko Anthony Robins Wickliffe C Abraham Source Type: research
Correction to TINS 1828 Contributions by metaplasticity to solving the Catastrophic Forgetting Problem: (Trends in Neurosciences, 45:9 p:656-666, 2022)
Trends Neurosci. 2023 Aug 18:S0166-2236(23)00173-X. doi: 10.1016/j.tins.2023.07.008. Online ahead of print.NO ABSTRACTPMID:37599184 | DOI:10.1016/j.tins.2023.07.008 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 20, 2023 Category: Neuroscience Authors: Peter Jedlicka Matus Tomko Anthony Robins Wickliffe C Abraham Source Type: research
Correction to TINS 1828 Contributions by metaplasticity to solving the Catastrophic Forgetting Problem: (Trends in Neurosciences, 45:9 p:656-666, 2022)
Trends Neurosci. 2023 Aug 18:S0166-2236(23)00173-X. doi: 10.1016/j.tins.2023.07.008. Online ahead of print.NO ABSTRACTPMID:37599184 | DOI:10.1016/j.tins.2023.07.008 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 20, 2023 Category: Neuroscience Authors: Peter Jedlicka Matus Tomko Anthony Robins Wickliffe C Abraham Source Type: research
Correction to TINS 1828 Contributions by metaplasticity to solving the Catastrophic Forgetting Problem: (Trends in Neurosciences, 45:9 p:656-666, 2022)
Trends Neurosci. 2023 Aug 18:S0166-2236(23)00173-X. doi: 10.1016/j.tins.2023.07.008. Online ahead of print.NO ABSTRACTPMID:37599184 | DOI:10.1016/j.tins.2023.07.008 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 20, 2023 Category: Neuroscience Authors: Peter Jedlicka Matus Tomko Anthony Robins Wickliffe C Abraham Source Type: research
The systemic immune response in Parkinson's disease: focus on the peripheral immune component
Trends Neurosci. 2023 Aug 17:S0166-2236(23)00165-0. doi: 10.1016/j.tins.2023.07.005. Online ahead of print.ABSTRACTDuring Parkinson's disease (PD), both the central nervous system (CNS) and peripheral nervous system (PNS) are affected. In parallel, innate immune cells respond early to neuronal changes and alpha-synuclein (α-syn) pathology. Moreover, some of the affected neuronal groups innervate organs with a relevant role in immunity. Consequently, not only microglia, but also peripheral immune cells are altered, resulting in a systemic immune response. Innate and adaptive immune cells may participate in the neurodegener...
Source: Trends in Neurosciences - August 19, 2023 Category: Neuroscience Authors: Johanne Lauritsen Marina Romero-Ramos Source Type: research
The systemic immune response in Parkinson's disease: focus on the peripheral immune component
Trends Neurosci. 2023 Aug 17:S0166-2236(23)00165-0. doi: 10.1016/j.tins.2023.07.005. Online ahead of print.ABSTRACTDuring Parkinson's disease (PD), both the central nervous system (CNS) and peripheral nervous system (PNS) are affected. In parallel, innate immune cells respond early to neuronal changes and alpha-synuclein (α-syn) pathology. Moreover, some of the affected neuronal groups innervate organs with a relevant role in immunity. Consequently, not only microglia, but also peripheral immune cells are altered, resulting in a systemic immune response. Innate and adaptive immune cells may participate in the neurodegener...
Source: Trends in Neurosciences - August 19, 2023 Category: Neuroscience Authors: Johanne Lauritsen Marina Romero-Ramos Source Type: research
Evolutionary neuroanatomical expansion of Broca's region serving a human-specific function
This article presents an evolutionary neuroanatomical framework which may offer a solution to this dispute. It is proposed that in humans, Broca's region houses language and action independently in spatially separated subregions. This became possible due to an evolutionary expansion of Broca's region in the human brain, which was not paralleled by a similar expansion in the chimpanzee's brain, providing additional space needed for the neural representation of language in humans.PMID:37596132 | DOI:10.1016/j.tins.2023.07.004 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 18, 2023 Category: Neuroscience Authors: Angela D Friederici Source Type: research
Alzheimer's disease and related tauopathies: disorders of disrupted neuronal identity
Trends Neurosci. 2023 Aug 15:S0166-2236(23)00166-2. doi: 10.1016/j.tins.2023.07.006. Online ahead of print.ABSTRACTPostmitotic neurons require persistently active controls to maintain terminal differentiation. Unlike dividing cells, aberrant cell cycle activation in mature neurons causes apoptosis rather than transformation. In Alzheimer's disease (AD) and related tauopathies, evidence suggests that pathogenic forms of tau drive neurodegeneration via neuronal cell cycle re-entry. Multiple interconnected mechanisms linking tau to cell cycle activation have been identified, including, but not limited to, tau-induced overstab...
Source: Trends in Neurosciences - August 17, 2023 Category: Neuroscience Authors: Bess Frost Source Type: research
Alzheimer's disease and related tauopathies: disorders of disrupted neuronal identity
Trends Neurosci. 2023 Aug 15:S0166-2236(23)00166-2. doi: 10.1016/j.tins.2023.07.006. Online ahead of print.ABSTRACTPostmitotic neurons require persistently active controls to maintain terminal differentiation. Unlike dividing cells, aberrant cell cycle activation in mature neurons causes apoptosis rather than transformation. In Alzheimer's disease (AD) and related tauopathies, evidence suggests that pathogenic forms of tau drive neurodegeneration via neuronal cell cycle re-entry. Multiple interconnected mechanisms linking tau to cell cycle activation have been identified, including, but not limited to, tau-induced overstab...
Source: Trends in Neurosciences - August 17, 2023 Category: Neuroscience Authors: Bess Frost Source Type: research
Alzheimer's disease and related tauopathies: disorders of disrupted neuronal identity
Trends Neurosci. 2023 Aug 15:S0166-2236(23)00166-2. doi: 10.1016/j.tins.2023.07.006. Online ahead of print.ABSTRACTPostmitotic neurons require persistently active controls to maintain terminal differentiation. Unlike dividing cells, aberrant cell cycle activation in mature neurons causes apoptosis rather than transformation. In Alzheimer's disease (AD) and related tauopathies, evidence suggests that pathogenic forms of tau drive neurodegeneration via neuronal cell cycle re-entry. Multiple interconnected mechanisms linking tau to cell cycle activation have been identified, including, but not limited to, tau-induced overstab...
Source: Trends in Neurosciences - August 17, 2023 Category: Neuroscience Authors: Bess Frost Source Type: research
Gamma oscillations and episodic memory
Trends Neurosci. 2023 Aug 5:S0166-2236(23)00163-7. doi: 10.1016/j.tins.2023.07.003. Online ahead of print.ABSTRACTEnhanced gamma oscillatory activity (30-80 Hz) accompanies the successful formation and retrieval of episodic memories. While this co-occurrence is well documented, the mechanistic contributions of gamma oscillatory activity to episodic memory remain unclear. Here, we review how gamma oscillatory activity may facilitate spike timing-dependent plasticity, neural communication, and sequence encoding/retrieval, thereby ensuring the successful formation and/or retrieval of an episodic memory. Based on the evidence ...
Source: Trends in Neurosciences - August 7, 2023 Category: Neuroscience Authors: Benjamin J Griffiths Ole Jensen Source Type: research
Gamma oscillations and episodic memory
Trends Neurosci. 2023 Aug 5:S0166-2236(23)00163-7. doi: 10.1016/j.tins.2023.07.003. Online ahead of print.ABSTRACTEnhanced gamma oscillatory activity (30-80 Hz) accompanies the successful formation and retrieval of episodic memories. While this co-occurrence is well documented, the mechanistic contributions of gamma oscillatory activity to episodic memory remain unclear. Here, we review how gamma oscillatory activity may facilitate spike timing-dependent plasticity, neural communication, and sequence encoding/retrieval, thereby ensuring the successful formation and/or retrieval of an episodic memory. Based on the evidence ...
Source: Trends in Neurosciences - August 7, 2023 Category: Neuroscience Authors: Benjamin J Griffiths Ole Jensen Source Type: research
Gamma oscillations and episodic memory
Trends Neurosci. 2023 Aug 5:S0166-2236(23)00163-7. doi: 10.1016/j.tins.2023.07.003. Online ahead of print.ABSTRACTEnhanced gamma oscillatory activity (30-80 Hz) accompanies the successful formation and retrieval of episodic memories. While this co-occurrence is well documented, the mechanistic contributions of gamma oscillatory activity to episodic memory remain unclear. Here, we review how gamma oscillatory activity may facilitate spike timing-dependent plasticity, neural communication, and sequence encoding/retrieval, thereby ensuring the successful formation and/or retrieval of an episodic memory. Based on the evidence ...
Source: Trends in Neurosciences - August 7, 2023 Category: Neuroscience Authors: Benjamin J Griffiths Ole Jensen Source Type: research
Gamma oscillations and episodic memory
Trends Neurosci. 2023 Aug 5:S0166-2236(23)00163-7. doi: 10.1016/j.tins.2023.07.003. Online ahead of print.ABSTRACTEnhanced gamma oscillatory activity (30-80 Hz) accompanies the successful formation and retrieval of episodic memories. While this co-occurrence is well documented, the mechanistic contributions of gamma oscillatory activity to episodic memory remain unclear. Here, we review how gamma oscillatory activity may facilitate spike timing-dependent plasticity, neural communication, and sequence encoding/retrieval, thereby ensuring the successful formation and/or retrieval of an episodic memory. Based on the evidence ...
Source: Trends in Neurosciences - August 7, 2023 Category: Neuroscience Authors: Benjamin J Griffiths Ole Jensen Source Type: research
Gamma oscillations and episodic memory
Trends Neurosci. 2023 Aug 5:S0166-2236(23)00163-7. doi: 10.1016/j.tins.2023.07.003. Online ahead of print.ABSTRACTEnhanced gamma oscillatory activity (30-80 Hz) accompanies the successful formation and retrieval of episodic memories. While this co-occurrence is well documented, the mechanistic contributions of gamma oscillatory activity to episodic memory remain unclear. Here, we review how gamma oscillatory activity may facilitate spike timing-dependent plasticity, neural communication, and sequence encoding/retrieval, thereby ensuring the successful formation and/or retrieval of an episodic memory. Based on the evidence ...
Source: Trends in Neurosciences - August 7, 2023 Category: Neuroscience Authors: Benjamin J Griffiths Ole Jensen Source Type: research