Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

Cold blooded vertebrates help unveil a heat-dependent trigger
This study highlights the importance of considering natural diversity and comparative biology when approaching biophysical questions.PMID:37652839 | DOI:10.1016/j.tins.2023.08.005 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Sebastian E Brauchi Source Type: research

Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

Cold blooded vertebrates help unveil a heat-dependent trigger
This study highlights the importance of considering natural diversity and comparative biology when approaching biophysical questions.PMID:37652839 | DOI:10.1016/j.tins.2023.08.005 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Sebastian E Brauchi Source Type: research

Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

Cold blooded vertebrates help unveil a heat-dependent trigger
This study highlights the importance of considering natural diversity and comparative biology when approaching biophysical questions.PMID:37652839 | DOI:10.1016/j.tins.2023.08.005 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Sebastian E Brauchi Source Type: research

Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

Cold blooded vertebrates help unveil a heat-dependent trigger
This study highlights the importance of considering natural diversity and comparative biology when approaching biophysical questions.PMID:37652839 | DOI:10.1016/j.tins.2023.08.005 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Sebastian E Brauchi Source Type: research

Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

Cold blooded vertebrates help unveil a heat-dependent trigger
This study highlights the importance of considering natural diversity and comparative biology when approaching biophysical questions.PMID:37652839 | DOI:10.1016/j.tins.2023.08.005 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Sebastian E Brauchi Source Type: research

Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

Cold blooded vertebrates help unveil a heat-dependent trigger
This study highlights the importance of considering natural diversity and comparative biology when approaching biophysical questions.PMID:37652839 | DOI:10.1016/j.tins.2023.08.005 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Sebastian E Brauchi Source Type: research

Synapse organizers as molecular codes for synaptic plasticity
Trends Neurosci. 2023 Aug 29:S0166-2236(23)00188-1. doi: 10.1016/j.tins.2023.08.001. Online ahead of print.ABSTRACTSynapse organizing proteins are multifaceted molecules that coordinate the complex processes of brain development and plasticity at the level of individual synapses. Their importance is demonstrated by the major brain disorders that emerge when their function is compromised. The mechanisms whereby the various families of organizers govern synapses are diverse, but converge on the structure, function, and plasticity of synapses. Therefore, synapse organizers regulate how synapses adapt to ongoing activity, a pr...
Source: Trends in Neurosciences - August 31, 2023 Category: Neuroscience Authors: Steven A Connor Tabrez J Siddiqui Source Type: research

A critical period plasticity framework for the sensorimotor-association axis of cortical neurodevelopment
Trends Neurosci. 2023 Aug 28:S0166-2236(23)00167-4. doi: 10.1016/j.tins.2023.07.007. Online ahead of print.ABSTRACTTo understand human brain development it is necessary to describe not only the spatiotemporal patterns of neurodevelopment but also the neurobiological mechanisms that underlie them. Human neuroimaging studies have provided evidence for a hierarchical sensorimotor-to-association (S-A) axis of cortical neurodevelopment. Understanding the biological mechanisms that underlie this program of development using traditional neuroimaging approaches has been challenging. Animal models have been used to identify periods...
Source: Trends in Neurosciences - August 29, 2023 Category: Neuroscience Authors: Bart Larsen Valerie J Sydnor Arielle S Keller B T Thomas Yeo Theodore D Satterthwaite Source Type: research

A critical period plasticity framework for the sensorimotor-association axis of cortical neurodevelopment
Trends Neurosci. 2023 Aug 28:S0166-2236(23)00167-4. doi: 10.1016/j.tins.2023.07.007. Online ahead of print.ABSTRACTTo understand human brain development it is necessary to describe not only the spatiotemporal patterns of neurodevelopment but also the neurobiological mechanisms that underlie them. Human neuroimaging studies have provided evidence for a hierarchical sensorimotor-to-association (S-A) axis of cortical neurodevelopment. Understanding the biological mechanisms that underlie this program of development using traditional neuroimaging approaches has been challenging. Animal models have been used to identify periods...
Source: Trends in Neurosciences - August 29, 2023 Category: Neuroscience Authors: Bart Larsen Valerie J Sydnor Arielle S Keller B T Thomas Yeo Theodore D Satterthwaite Source Type: research