Editorial commentary: Use of cerebral embolic protection devices during transcatheter aortic valve replacement
Transcatheter aortic valve implantation (TAVI) is an alternative to surgical aortic valve replacement (SAVR) for severe aortic stenosis. Many of these patients have heavily calcified aortic valve and atherosclerotic or porcelain aorta. As reviewed by Vlastra et al. [1] in the present study, these patients are at very high risk for cerebrovascular events due to atherosclerotic and calcific debris embolization during manipulation of wire and large bore catheters in the atherosclerotic aorta as well as manipulation of calcific aortic valve during balloon valvuloplasty and transcatheter valve deployment. (Source: Trends in Car...
Source: Trends in Cardiovascular Medicine - February 5, 2018 Category: Cardiology Authors: Hemang B. Panchal, Timir K. Paul Source Type: research
Non-PCI/CABG therapies for refractory angina
We were pleased to read the article by Dr Ki and Dr Conti: Non-PCI/CABG therapies for refractory angina which was published in October 2017 [1]. The authors presented an excellent review on the currently available and the emerging novel therapies for refractory angina pectoris (RAP). (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - February 5, 2018 Category: Cardiology Authors: Yoav Paz, Amihay Shinfeld Tags: Letter to the Editor Source Type: research
Editorial commentary: Use of cerebral embolic protection devices during transcatheter aortic valve replacement
Transcatheter aortic valve implantation (TAVI) is an alternative to surgical aortic valve replacement (SAVR) for severe aortic stenosis. Many of these patients have heavily calcified aortic valve and atherosclerotic or porcelain aorta. As reviewed by Vlastra et al. [1] in the present study, these patients are at very high risk for cerebrovascular events due to atherosclerotic and calcific debris embolization during manipulation of wire and large bore catheters in the atherosclerotic aorta as well as manipulation of calcific aortic valve during balloon valvuloplasty and transcatheter valve deployment. (Source: Trends in Car...
Source: Trends in Cardiovascular Medicine - February 5, 2018 Category: Cardiology Authors: Hemang B. Panchal, Timir K. Paul Source Type: research
Use of Cerebral Embolic Protection Devices during Transcatheter Aortic Valve Replacement
Transcatheter aortic valve implantation (TAVI) is an alternative to surgical aortic valve replacement (SAVR) for severe aortic stenosis. Many of these patients have heavily calcified aortic valve and atherosclerotic or porcelain aorta. As reviewed by Vlastra et al. in the present study, these patients are at very high risk for cerebrovascular events due to atherosclerotic and calcific debris embolization during manipulation of wire and large bore catheters in the atherosclerotic aorta as well as manipulation of calcific aortic valve during balloon valvuloplasty and transcatheter valve deployment [1]. (Source: Trends in Car...
Source: Trends in Cardiovascular Medicine - February 5, 2018 Category: Cardiology Authors: Hemang B. Panchal, Timir K. Paul Source Type: research
Letter to the editor
We were pleased to read the article by Dr Ki and Dr Conti: Non-PCI/CABG therapies for refractory angina which was published in October 2017 [1]. The authors presented an excellent review on the currently available and the emerging novel therapies for refractory angina pectoris (RAP). (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - February 5, 2018 Category: Cardiology Authors: Yoav Paz, Amihay Shinfeld Source Type: research
Editorial commentary: Heart failure with preserved ejection fraction —Clinical syndrome with incomplete understanding
Heart failure with preserved ejection fraction (HFpEF) is widely prevalent, representing approximately 50% of heart failure admissions [1]; however, the pathophysiology of HFpEF is still incompletely understood. Adding to this conundrum are limited therapeutic options for this condition. In this issue of Trends in Cardiovascular Medicine, Xanthipoulos et al. [2] summarize our current understanding of the disease. They propose a simplified classification system for HFpEF into two groups —hypertensive versus non-hypertensive and highlight the available diagnostic tools and potential therapeutic options for this condition. ...
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Supriya Shore, Paul J. Mather Source Type: research
Potentialities of the internal mammary arteries and refractory angina
Dear Editor, (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Marco Picich è Tags: Letter to the Editor Source Type: research
Cerebral protection devices during transcatheter aortic valve implantation
Transcatheter aortic valve implantation (TAVI) in patients with aortic valve stenosis is associated with an improvement of clinical outcomes, quality of life, and self-sufficiency. The most feared TAVI-related complication is the occurrence of stroke. In order to reduce peri-procedural cerebral embolizations, diverse cerebral protection devices have been developed. These devices work though deflection or filtering of emboli, and are in different stages of testing. Silent cerebral infarctions identified by diffusion-weighted magnetic resonance imaging (DW-MRI) are used as surrogate primary outcomes, but the clinical signifi...
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Wieneke Vlastra, Jeroen Vendrik, Karel T. Koch, Jan Baan, Jan J. Piek, Ronak Delewi Source Type: research
Editorial commentary: The lower the LDL the better but how and how much?
In this issue of Trends in Cardiovascular Medicine, in a comprehensive review, Packard concludes that the lower the level of low-density lipoprotein cholesterol (LDL), the better [1]. This finding should be viewed in the context of the totality of evidence. In descriptive studies, useful to formulate, but not test, hypotheses, before the introduction of western lifestyles, the majority of the adult population of the world had LDLs of about 50mg per deciliter (mg/dL). Japan has had the longest life expectancy in the world as well as the history of the world, due mainly to very low rates of coronary heart disease (CHD). (Sou...
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Alexander Gitin, Marc A. Pfeffer, Charles H. Hennekens Source Type: research
Emerging concepts in diagnosis and treatment of syncope by pacing
Neuroendocrine syncope is a newly proposed term to embody both syncope of reflex and adenosine-related etiology. Recent publications on tilt testing have revealed the presence of a hypotensive tendency in some patients, even in the face of severe cardioinhibition. This new understanding may allow better selection of older reflex syncope patients, documented by ECG loop recorder, for successful pacing where tilt testing is ideally negative for a good result in terms of few syncope recurrences and prompts a less aggressive management policy when hypotensive medication is required. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Richard Sutton, Jean-Claude Deharo, Michele Brignole, Mohamed H. Hamdan Source Type: research
Editorial commentary: Heart failure with preserved ejection fraction —Clinical syndrome with incomplete understanding
Heart failure with preserved ejection fraction (HFpEF) is widely prevalent, representing approximately 50% of heart failure admissions [1]; however, the pathophysiology of HFpEF is still incompletely understood. Adding to this conundrum are limited therapeutic options for this condition. In this issue of Trends in Cardiovascular Medicine, Xanthipoulos et al. [2] summarize our current understanding of the disease. They propose a simplified classification system for HFpEF into two groups —hypertensive versus non-hypertensive and highlight the available diagnostic tools and potential therapeutic options for this condition. ...
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Supriya Shore, Paul J. Mather Source Type: research
Editorial commentary: The lower the LDL the better but how and how much?
In this issue of Trends in Cardiovascular Medicine, in a comprehensive review, Packard concludes that the lower the level of low-density lipoprotein cholesterol (LDL), the better [1]. This finding should be viewed in the context of the totality of evidence. In descriptive studies, useful to formulate, but not test, hypotheses, before the introduction of western lifestyles, the majority of the adult population of the world had LDLs of about 50mg per deciliter (mg/dL). Japan has had the longest life expectancy in the world as well as the history of the world, due mainly to very low rates of coronary heart disease (CHD). (Sou...
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Alexander Gitin, Marc A. Pfeffer, Charles H. Hennekens Source Type: research
Heart Failure With Preserved Ejection Fraction: Clinical Syndrome With Incomplete Understanding
Heart Failure with preserved ejection fraction (HFpEF) is widely prevalent, representing approximately 50% of heart failure admissions [1]; however, the pathophysiology of HFpEF is still incompletely understood. Adding to this conundrum are limited therapeutic options for this condition. In this issue of Trends in Cardiovascular Medicine, Xanthipoulos, Triposkiadis and Starling [2] summarize our current understanding of the disease. They propose a simplified classification system for HFpEF into two groups – hypertensive versus non-hypertensive and highlight the available diagnostic tools and potential therapeutic options...
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Supriya Shore, Paul J. Mather Source Type: research
Potentialities of the internal mammary arteries and refractory angina
Dear Editor, (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - February 2, 2018 Category: Cardiology Authors: Marco Picich è Tags: Letter to the Editor Source Type: research
