Percutaneous edge-to-edge mitral valve repair with Mitraclip: State of the art and new perspectives
Mitral regurgitation (MR) is a complex pathology affecting a large and progressively increasing portion of the worldwide population as a result of its ageing, with impact not only on quality of life, but also on survival. On an etiological basis, MR can be divided into two groups: organic mitral regurgitation (OMR) and functional mitral regurgitation (FMR). In OMR, the disease directly involves the valve (leaflets, annulus, subvalvular apparatus) and the optimal therapy is the surgical correction of the valve lesions. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - September 27, 2017 Category: Cardiology Authors: Flavia Ballocca Source Type: research
Heart failure management with ambulatory pulmonary artery pressure monitoring
Remote monitoring strategies have been developed to improve ambulatory care of heart failure patients and reduce heart failure hospitalizations. This manuscript evaluates the CardioMEMS device, an implantable wireless pulmonary artery pressure monitor. We provide a historical review of remote monitoring in heart failure along with an in-depth analysis of the rationale, evidence, and limitations of the CardioMEMS device. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - September 15, 2017 Category: Cardiology Authors: Alexander T. Sandhu, Paul A. Heidenreich Source Type: research
Editorial commentary: Wearable Devices and Personalized Healthcare
Wearable medical devices have been in use for many years to obtain information about patients outside the constrained environment of the hospital or office. For example, the use of such devices has allowed the detection of episodic arrhythmias that might not be detected by short-term monitoring. Evolving technology now allows us to obtain many more kinds of data, and new opportunities to help patients. Much effort in the use of wearable devices has focused on “healthy” patients monitoring themselves with a goal of improving physical fitness or reducing risk factors, sometimes referred to as the “quantified self” mo...
Source: Trends in Cardiovascular Medicine - September 11, 2017 Category: Cardiology Authors: Martin Steven Kohn Source Type: research
Wearable Devices and Personalized Healthcare
Wearable medical devices have been in use for many years to obtain information about patients outside the constrained environment of the hospital or office. For example, the use of such devices has allowed the detection of episodic arrhythmias that might not be detected by short term monitoring. Evolving technology now allows us to obtain many more kinds of data, and new opportunities to help patients. Much effort in the use of wearable devices has focused on “healthy” patients monitoring themselves with a goal of improving physical fitness or reducing risk factors, sometimes referred to as the “quantified self” mo...
Source: Trends in Cardiovascular Medicine - September 11, 2017 Category: Cardiology Authors: Martin Steven Kohn Source Type: research
Heart failure in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a constellation of cardiovascular (CV) and non-CV manifestations. Even though CV complications such as accelerated atherosclerosis and elevated risk of myocardial infarction (MI) have been recognized for many years, there is limited evidence regarding SLE and its association with heart failure (HF). Traditional risk factors of atherosclerotic CV disease, as well as various SLE manifestations and therapies, independently or together, increase the risk of HF in this population. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - September 5, 2017 Category: Cardiology Authors: Bishnu P. Dhakal, Chang H. Kim, Sadeer G. Al-Kindi, Guilherme H. Oliveira Source Type: research
Editorial Board
(Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - August 31, 2017 Category: Cardiology Source Type: research
Table of Contents
(Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - August 31, 2017 Category: Cardiology Source Type: research
Editorial commentary: The air that I breathe ……………..makes me sick!
According to the ‘Environmental Burden of Disease in European Countries’ project report, particulate matter air pollution, together with traffic noise pollution, contribute to 75% of the burden of disease attributable to environmental factors [1]. With growing urbanization, the degree to which people are exposed simultaneously to these factors is likely to further increase in the future, particularly in developing countries. Currently, 17 megacities in Asia rank among the top 30 cities in terms of premature cardiovascular mortality and account for 7% of the global burden of disease attributable to outdoor air pollution...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Thomas M ünzel Source Type: research
Editorial commentary: What can lung transplantation teach us about the mechanisms of atrial arrhythmias?
Lung transplantation is an increasingly performed procedure, with 50% survival at 5 years [1] and whose immediate and long-term prognosis may be complicated by atrial arrhythmias. Operatively, the procedure involves transplantation of one or both lungs with their proximal airways, together with anastomosis of the vascular pedicle (pulmonary veins and arteries) to the recipient heart. This results in surgical isolation of the donor pulmonary veins to the recipient left atrium, providing a valuable opportunity to examine incident atrial fibrillation (AF) and its mechanistic relation to the pulmonary veins [2]. (Source: Trend...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Tina Baykaner, Albert J. Rogers, Junaid A.B. Zaman, Sanjiv M. Narayan Source Type: research
Editorial commentary: Let it snow —Emerging roles for snoRNAs in cardiovascular disease
Despite prevention and current therapies, cardiovascular disease and its attendant complications remains the number one cause of morbidity and mortality in Western societies. While current therapeutics target protein-coding genes representing 2% of the genome, accumulating studies reveal that a large portion of the non-coding genome is actively transcribed and ~50% of these transcripts are small RNAs and long non-coding RNAs [1,2]. Emerging studies have begun to unravel specific species of non-coding RNAs as critical mediators of pathological signaling pathways and cellular responses important for a range of cardiovascular...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Mark W. Feinberg Source Type: research
Editorial commentary: TAVR —Is there a path to an all-surgical-risk indication?
Transcatheter aortic valve replacement (TAVR) has now become the standard of care for the treatment of severe symptomatic aortic valve stenosis in patients who are thought to be at least high surgical risk, and is an approved approach for patients who are at intermediate risk [1 –3]. The result of the PARTNER 2 (Placement of AoRTic TraNscathetER Valve Trial) trial provided support to the use of TAVR for patients with intermediate surgical risk [4]. The results of the SURTAVI trial led to the Food and Drug Administration (FDA) approval of the self-expandable valve for use in intermediate-risk category in the United States...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Sameer Arora, John P. Vavalle Source Type: research
Let it snow: Emerging roles for snoRNAs in cardiovascular disease
Despite prevention and current therapies, cardiovascular disease and its attendant complications remains the number one cause of morbidity and mortality in Western societies. While current therapeutics target protein-coding genes representing 2% of the genome, accumulating studies reveal that a large portion of the non-coding genome is actively transcribed and ~50% of these transcripts are small RNAs and long non-coding RNAs [1,2]. Emerging studies have begun to unravel specific species of non-coding RNAs as critical mediators of pathological signaling pathways and cellular responses important for a range of cardiovascular...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Mark W. Feinberg Source Type: research
What Can Lung Transplantation Teach Us About the Mechanisms of Atrial Arrhythmias?
Lung transplantation is an increasingly performed procedure, with 50% survival at 5 years1 and whose immediate and long-term prognosis may be complicated by atrial arrhythmias. Operatively, the procedure involves transplantation of one or both lungs with their proximal airways, together with anastomosis of the vascular pedicle (pulmonary veins and arteries) to the recipient heart. This results in surgical isolation of the donor pulmonary veins to the recipient left atrium, providing a valuable opportunity to examine incident atrial fibrillation (AF) and its mechanistic relation to the pulmonary veins. (Source: Trends in Ca...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Tina Baykaner, Albert J. Rogers, Junaid A.B. Zaman, Sanjiv M. Narayan Source Type: research
TAVR: Is There a Path to an All-Surgical-Risk Indication?
Transcatheter aortic valve replacement (TAVR) has now become the standard of care for the treatment of severe symptomatic aortic valve stenosis in patients who are thought to be at least high surgical risk, and is an approved approach for patients who are at intermediate risk.1 –3 The result of the PARTNER 2 (Placement of AoRTic TraNscathetER Valve Trial) trial provided support to the use of TAVR for patients with intermediate surgical risk.4 The results of the SURTAVI trial led to the Food and Drug Administration (FDA) approval of the self-expandable valve for use in in termediate-risk category in the United States. (So...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: By Sameer Arora, John P. Vavalle Source Type: research
Editorial: The air that I breathe ……………..makes me sick!
According to the ‘Environmental Burden of Disease in European Countries’ project report, particulate matter air pollution, together with traffic noise pollution, contribute to 75% of the burden of disease attributable to environmental factors.1 With growing urbanization, the degree to which people are exposed si multaneously to these factors is likely to further increase in the future, particularly in developing countries. Currently, 17 megacities in Asia rank among the top 30 cities in terms of premature cardiovascular mortality and account for 7% of the global burden of disease attributable to outdoor air pollution a...
Source: Trends in Cardiovascular Medicine - August 28, 2017 Category: Cardiology Authors: Thomas M ünzel Source Type: research
