Thymidine phosphorylase: A potential new target for treating cardiovascular disease
We recently found that thymidine phosphorylase (TYMP), also known as platelet-derived endothelial cell growth factor, plays an important role in platelet activation in vitro and thrombosis in vivo by participating in multiple signaling pathways. Platelets are a major source of TYMP. Since platelet-mediated clot formation is a key event in several fatal diseases, such as myocardial infarction, stroke and pulmonary embolism, understanding TYMP in depth may lead to uncovering novel mechanisms in the development of cardiovascular diseases. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 20, 2017 Category: Cardiology Authors: Wei Li, Hong Yue Source Type: research
MY APPROACH to the pregnant patient with a supraventricular tachycardia ⁎
Samuel J. Asirvatham, MD, FACC, FHRS (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 11, 2017 Category: Cardiology Authors: Samuel J. Asirvatham, Vaibhav R. Vaidya Tags: MY APPROACH Source Type: research
MY APPROACH to the Pregnant Patient With a Supraventricular Tachycardia
Arrhythmias can cause cardiovascular complications in pregnancy. Palpitations are a common symptom in pregnancy, and electrocardiography (ECG) or ambulatory ECG monitoring can be conducted to determine correlation of the symptoms with arrhythmias. The differential diagnosis for supraventricular tachycardia (SVT) in pregnant patients is similar to that for non-pregnant patients, and includes atrioventricular nodal reentrant tachycardia (AVNRT), atrioventricular reentrant tachycardia (AVRT), atrial fibrillation (AF) or flutter, and atrial tachycardia (AT). (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 11, 2017 Category: Cardiology Authors: Samuel J. Asirvatham, Vaibhav R. Vaidya Tags: MY APPROACH Source Type: research
Editorial Board
(Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 7, 2017 Category: Cardiology Source Type: research
Table of Contents
(Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 7, 2017 Category: Cardiology Source Type: research
Editorial Commentary: The optimistic future of remote hemodynamic monitoring
‘It's getting better all the time. A little better all the time.’ The Beatles (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Aaron M. Wolfson, David M. Shavelle Source Type: research
MY APPROACH to the Athlete With Wolff-Parkinson-White Syndrome (WPW)*
Aaron L. Baggish, MD (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Aaron L. Baggish, Ankit B. Shah Tags: MY APPROACH Source Type: research
MY APPROACH to the patient with heart failure and improved ejection fraction ⁎
Jay N. Cohn, MD, FAHA (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Jay N. Cohn Tags: MY APPROACH Source Type: research
MY APPROACH to the patient with left main disease*
Eric R. Bates, MD (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Eric R. Bates Tags: My Approach Source Type: research
The Optimistic Future of Remote Hemodynamic Monitoring
In this issue of Trends in Cardiovascular Medicine, Sandhu and Heidenreich1 provide a concise, extensive and objective review of remote hemodynamic monitoring (RHM) with the CardioMEMS ™ HF device. RHM has long been considered a potential treatment to improve the care of patients with advanced heart failure (HF). A multitude of devices assessing various physiologic variables related to the process of HF decompensation have been studied.2 However, until recently, no device or app roach has been effective in reducing future HF hospitalization rates. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Aaron M. Wolfson, David M. Shavelle Source Type: research
MY APPROACH to the Athlete With Wolff-Parkinson-White Syndrome (WPW)
There are two initial considerations during evaluation of an athlete with electrocardiographic evidence of ventricular pre-excitation, a finding characterized by a shortened PR-interval ( (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Aaron L. Baggish, Ankit B. Shah Tags: MY APPROACH Source Type: research
MY APPROACH to the Patient With Heart Failure and Improved Ejection Fraction
Patients with signs and symptoms of heart failure associated with echocardiographic evidence of a dilated left ventricle and a low ejection fraction (usually less than 35% or at least (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Jay N. Cohn Tags: MY APPROACH Source Type: research
My Approach to the Patient With Left Main Disease
Coronary artery bypass graft surgery (CABG) has historically been recommended over percutaneous coronary artery intervention (PCI) as the preferred revascularization strategy for patients with significant unprotected left main coronary artery disease (CAD). However, PCI has more recently become a treatment option in selected patients with left main CAD who do not have extensive or complex CAD in the other coronary arteries. When equipoise is present, the 30-day rates for death, myocardial infarction (MI), and stroke will be lower with PCI, and CABG will have a higher risk for bleeding and infection and longer hospital and ...
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: Eric R. Bates Tags: MY APPROACH Source Type: research
MY Approach to the Elderly Patient With Resistant Hypertension
When trying to understand the etiology of resistant hypertension in older adults (ie,>70 years of age), one needs to ask the following questions: (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - October 3, 2017 Category: Cardiology Authors: George L. Bakris Tags: MY APPROACH Source Type: research
Editorial commentary: Percutaneous edge-to-edge mitral valve repair with Mitraclip: State of the art and new perspectives
Mitral regurgitation (MR) is a complex pathology affecting a large and progressively increasing portion of the worldwide population as a result of its ageing, with impact not only on quality of life, but also on survival. On an etiological basis, MR can be divided into two groups: organic mitral regurgitation (OMR) and functional mitral regurgitation (FMR). In OMR, the disease directly involves the valve (leaflets, annulus, and subvalvular apparatus) and the optimal therapy is the surgical correction of the valve lesions. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - September 27, 2017 Category: Cardiology Authors: Flavia Ballocca Source Type: research
