The Selective Estrogen Receptor Modulator, Raloxifene, Is Protective Against Renal Ischemia–reperfusion Injury
Conclusions. Raloxifene is protective against both acute kidney injury and fibrosis resulting from renal IRI in a mouse model. (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Original Basic Science Source Type: research

Dysbiosis of the Female Murine Gut Microbiome Exacerbates Neutrophil-mediated Vascular Allograft Injury by Affecting Immunoregulation by Acetate
Conclusions. Dysbiosis of the gut microbiome that reduces its production of the immunoregulatory metabolite acetate exacerbates neutrophil-mediated allograft vascular injury. (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Original Basic Science Source Type: research

A Review of Direct-acting Oral Anticoagulants and Their Use in Solid Organ Transplantation
Direct-acting oral anticoagulant (DOAC) use has increased dramatically since their introduction because of the growing evidence of proven efficacy and enhanced safety compared with warfarin and the low-molecular-weight heparins in the general population. Unfortunately, there is a dearth of quality data regarding the safety and efficacy of the DOACs in patients awaiting organ transplant and those who received a solid organ transplant. This review aims to evaluate the available literature and considerations regarding anticoagulation use in transplant recipients, focusing on preoperative, perioperative, and postoperative DOAC...
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Reviews Source Type: research

Challenges and Opportunities in the Supply of Living Kidney Donation in the UK National Health Service: An Economic Perspective
This article provides an economic perspective on issues pertinent to living kidney donation and transplantation. Although ethics, equity, and cultural considerations often seem at odds with economic concepts around resource allocation, this article explains the situation around supply and demand for living kidneys and illustrates how this has been addressed in the economic literature. The article discusses different policy recommendations for resolving the imbalance between supply and demand in kidney donation, through policies under 3 main approaches: increasing supply, decreasing demand, and improving the allocation of k...
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Reviews Source Type: research

Are MELD and MELDNa Still Reliable Tools to Predict Mortality on the Liver Transplant Waiting List?
Liver transplantation is the only curative treatment for end-stage liver disease. Unfortunately, the scarcity of donor organs and the increasing pool of potential recipients limit access to this life-saving procedure. Allocation should account for medical and ethical factors, ensuring equal access to transplantation regardless of recipient’s gender, race, religion, or income. Based on their short-term prognosis prediction, model for end-stage liver disease (MELD) and MELD sodium (MELDNa) have been widely used to prioritize patients on the waiting list for liver transplantation resulting in a significant decrease in waiti...
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Reviews Source Type: research

A New Look at an Old Problem: Is Single Lung Transplantation an Option in Candidates With Significant Secondary Pulmonary Hypertension?
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Commentaries Source Type: research

Increasing Living Liver Donor Pools: Liver Paired Exchange Versus ABO-incompatible Living Donor Liver Transplantation
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: Commentaries Source Type: research

The Reality of Inadequate Patient Care and the Need for a Global Action Framework in Organ Donation and Transplantation
Conclusions. This document can be used in governmental and policy circles as a call to action and as a checklist for actions needed to enable organ transplantation as treatment for organ failure. (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: Meeting Report Source Type: research

Social Media in Transplantation: An Opportunity for Outreach, Research Promotion, and Enhancing Workforce Diversity
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: Expert Insights Source Type: research

Finding the Road to Rome in Cardiac Allograft Vasculopathy Imaging Surveillance
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: Expert Insights Source Type: research

Tomoaki Kato, MD, MBA, FACS, The Marathon Surgeon
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: People in Transplantation Source Type: research

Sugar-coated Antigens Generated During Pregnancy Mediate Fetomaternal Tolerance
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: Game Changer Source Type: research

Research Highlights
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: Research Highlights Source Type: research

Vascularized Composite Allograft Transplantation in the United States: Current State of the Field and Future Challenges
No abstract available (Source: Transplantation)
Source: Transplantation - October 28, 2022 Category: Transplant Surgery Tags: In View: Around the World Source Type: research

Bebtelovimab for Treatment of COVID-19 in Ambulatory Solid Organ Transplant Recipients
No abstract available (Source: Transplantation)
Source: Transplantation - October 1, 2022 Category: Transplant Surgery Tags: Letters to the Editor Source Type: research