The evidence and rationale for the perioperative use of loop diuretics during kidney transplantation: A comprehensive review
Loop diuretics (LD) attenuate ischemic injury in nephrons. They are thought to decrease delayed graft function (DGF) during kidney transplantation (KT). This review aimed to summarize the current evidence for the perioperative use of LD during KT. (Source: Transplantation Reviews)
Source: Transplantation Reviews - November 23, 2017 Category: Transplant Surgery Authors: Shaifali Sandal, Pannya Bansal, Marcelo Cantarovich Source Type: research
The evidence and rationale for the perioperative use of loop diuretics during kidney transplantation: a comprehensive review
Loop diuretics (LD) attenuate ischemic injury in nephrons. They are thought to decrease delayed graft function (DGF) during kidney transplantation (KT). This review aimed to summarize the current evidence for the perioperative use of LD during KT. (Source: Transplantation Reviews)
Source: Transplantation Reviews - November 23, 2017 Category: Transplant Surgery Authors: Shaifali Sandal, Pannya Bansal, Marcelo Cantarovich Tags: Review article Source Type: research
Is carotid revascularization worthwhile in patients waiting for kidney transplantation?
Renal failure and haemodialysis are associated with an increased risk of cardiovascular disease. Patients undergoing renal transplantation undergo rigorous pre-operative vascular assessment, including optimisation of risk factors for stroke. The indication for carotid intervention and the threshold for carotid endarterectomy in asymptomatic patients with incidental carotid disease has not been clarified in the context chronic kidney disease (CKD). This review aims to analyse outcomes following carotid endarterectomy in patients with CKD, in order to ascertain whether general guidelines for carotid artery revascularisation ...
Source: Transplantation Reviews - November 15, 2017 Category: Transplant Surgery Authors: Peter Balaz, Petrut Gogalniceanu, Chris Callaghan Source Type: research
Cancer Evaluation in the Assessment of Solid Organ Transplant Candidates: A Systematic Review of Clinical Practice Guidelines
Active malignancies are a contraindication to transplantation, as immunosuppression can lead to worse cancer outcomes; therefore, ensuring transplant candidates are free of malignancy before transplantation is essential. This systematic review assesses the availability, quality, and consistency of recommended cancer evaluation prior to transplantation in Clinical Practice Guidelines (CPGs) for the selection of solid organ transplant candidates. (Source: Transplantation Reviews)
Source: Transplantation Reviews - November 7, 2017 Category: Transplant Surgery Authors: Sergio A. Acuna, Winnie Lam, Corinne Daly, S. Joseph Kim, Nancy N. Baxter Tags: Review article Source Type: research
De Novo Thrombotic Microangiopathy after Kidney Transplantation
Thrombotic microangiopathy (TMA) is a serious complication of transplantation that adversely affects kidney transplant recipient and allograft survival. Post-transplant TMA is usually classified into two categories: 1) recurrent TMA and 2) de novo TMA. Atypical hemolytic uremic syndrome (aHUS) resulting from dysregulation and over-activation of the alternate complement pathway is a rare disease but the most common diagnosis associated with recurrence in the allografts. De novo TMA, on the other hand, represents an overwhelming majority of the cases of post-transplant TMA and is a substantially more heterogeneous entity tha...
Source: Transplantation Reviews - November 4, 2017 Category: Transplant Surgery Authors: Neetika Garg, Helmut G. Rennke, Martha Pavlakis, Kambiz Zandi-Nejad Tags: Review article Source Type: research
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Source: Transplantation Reviews - October 1, 2017 Category: Transplant Surgery Source Type: research
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Source: Transplantation Reviews - October 1, 2017 Category: Transplant Surgery Source Type: research
Table of Contents
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Source: Transplantation Reviews - October 1, 2017 Category: Transplant Surgery Source Type: research
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Source: Transplantation Reviews - October 1, 2017 Category: Transplant Surgery Source Type: research
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Source: Transplantation Reviews - October 1, 2017 Category: Transplant Surgery Source Type: research
Primary care interventions to encourage organ donation registration: a systematic review
Previous research has proposed that primary care interventions to increase organ donation rates can help address the discrepancy between organ donation rates and the number of patients awaiting transplant. However, no systematic review has been conducted to examine interventions in this setting. (Source: Transplantation Reviews)
Source: Transplantation Reviews - September 2, 2017 Category: Transplant Surgery Authors: Catrin Pedder Jones, Chris Papadopoulos, Gurch Randhawa Tags: Review article Source Type: research
The Epigenetic Promise to Improve Prognosis of Heart Failure and Heart Transplantation
Heart transplantation (HT) remains the gold standard treatment for end-stage heart failure (HF) ensuring the highest long-term survival; however, due to the shortage of organ donors, the left ventricular assist device (LVAD) provides a backup strategy for patients as bridge to transplantation or when clinical contraindications are present [1,2]. HF represents the end-stage of several cardiac pathological conditions including atherosclerosis, coronary heart disease (CHD) and dilated, hypertrophic and restrictive cardiomyopathies [3-5]. (Source: Transplantation Reviews)
Source: Transplantation Reviews - August 15, 2017 Category: Transplant Surgery Authors: Chiara Sabia, Antonietta Picascia, Vincenzo Grimaldi, Cristiano Amarelli, Ciro Maiello, Claudio Napoli Tags: Review article Source Type: research
Defining the Phenotype of Antibody-Mediated Rejection in Kidney Transplantation: Advances in Diagnosis of Antibody Injury
The diagnostic criteria for antibody-mediated rejection (ABMR) are constantly evolving in light of the evidence. Inclusion of C4d-negative ABMR has been one of the major advances in the Banff Classification in recent years. Currently Banff 2015 classification requires evidence of donor specific antibodies (DSA), interaction between DSA and the endothelium, and acute tissue injury (in the form of microvasculature injury (MVI); acute thrombotic microangiopathy; or acute tubular injury in the absence of other apparent cause). (Source: Transplantation Reviews)
Source: Transplantation Reviews - August 14, 2017 Category: Transplant Surgery Authors: Neetika Garg, Milagros D. Samaniego, Dana Clark, Arjang Djamali Tags: Review article Source Type: research
Osteoporosis following heart transplantation and immunosuppressive therapy
Heart transplantation (HT) remains the ultimate final therapy for patients with end-stage heart failure, who despite optimal medical and surgical treatments exhibit severe symptoms. To prevent rejection of the transplanted organ, HT patients require life-long immunosuppressive therapy. The goal of the immunosuppression is to minimise the risk of immune-mediated graft rejection, while avoiding clinical side-effects. Current immunosuppressive agents have yielded good survival outcome, however, complications of the immunosuppressive therapy, such as impaired bone strength and increased fracture risk, are common among HT patie...
Source: Transplantation Reviews - August 12, 2017 Category: Transplant Surgery Authors: Eveline L öfdahl, Göran Rådegran Tags: Review article Source Type: research
