Preserving and perfusing the allograft pancreas: Past, present, and future
The concept of organ preservation by perfusion dates back to the mid-19th century. Innovations since then have included temperature regulation, perfusion fluid composition and various pumping systems. Advances made in liver, heart and kidney machine preservation are now contributing to increased graft utilisation, assessment of graft viability and potentially improved graft survival. Pancreas transplantation has not benefitted to the same extent from the application of perfusion technology, although the need is just as great. (Source: Transplantation Reviews)
Source: Transplantation Reviews - March 6, 2018 Category: Transplant Surgery Authors: Shamik Dholakia, Elisabeth Royston, Edward J. Sharples, Visesh Sankaran, Rutger J. Ploeg, Peter J. Friend Tags: Review article Source Type: research
Preserving and Perfusing the Allograft Pancreas: Past, Present, and Future
The concept of organ preservation by perfusion dates back to the mid-19th century. Innovations since then have included temperature regulation, perfusion fluid composition and various pumping systems. Advances made in liver, heart and kidney machine preservation are now contributing to increased graft utilisation, assessment of graft viability and potentially improved graft survival. Pancreas transplantation has not benefitted to the same extent from the application of perfusion technology, although the need is just as great. (Source: Transplantation Reviews)
Source: Transplantation Reviews - March 6, 2018 Category: Transplant Surgery Authors: Shamik Dholakia, Elisabeth Royston, Edward J. Sharples, Visesh Sankaran, Rutger J. Ploeg, Peter J. Friend Tags: Review article Source Type: research
Innate networking: Thrombotic microangiopathy, the activation of coagulation and complement in the sensitized kidney transplant recipient
Thrombotic microangiopathy (TMA) is a histological feature of antibody-mediated rejection and has the potential to cause problematic graft dysfunction, particularly for highly sensitized cross-match positive kidney transplant recipients. Prompt recognition of pertinent histopathological and systemic features of TMA in kidney transplantation is necessary. Underlying mechanisms of this process involve the activation of both complement and coagulation systems as a response to HLA antibody. As serine proteases, coagulation and complement cascades exhibit similar characteristics with respect to homeostatic function. (Source: Tr...
Source: Transplantation Reviews - February 10, 2018 Category: Transplant Surgery Authors: Miriam Manook, Jean Kwun, Steven Sacks, Anthony Dorling, Nizam Mamode, Stuart Knechtle Tags: Review article Source Type: research
Renal scintigraphy for post-transplant monitoring after kidney transplantation
Clinicians use several diagnostic modalities to recognize post-transplant complications, such as acute tubular necrosis, acute rejection, urologic and vascular complications. Currently, there is no consensus about the best procedural approach to evaluate post-transplant renal dysfunction. Renal needle-biopsy is often required, however, this is invasive and may lead to sample errors and complications, and most clinicians prefer using one of the noninvasive diagnostic modalities. (Source: Transplantation Reviews)
Source: Transplantation Reviews - December 28, 2017 Category: Transplant Surgery Authors: S. Benjamens, S.P. Berger, A.W.J.M. Glaudemans, J.S.F. Sanders, R.A. Pol, R.H.J.A. Slart Source Type: research
Renal Scintigraphy for Post-Transplant Monitoring after Kidney Transplantation
Clinicians use several diagnostic modalities to recognize post-transplant complications, such as acute tubular necrosis, acute rejection, urologic and vascular complications. Currently, there is no consensus about the best procedural approach to evaluate post-transplant renal dysfunction. Renal needle-biopsy is often required, however, this is invasive and may lead to sample errors and complications, and most clinicians prefer using one of the noninvasive diagnostic modalities. (Source: Transplantation Reviews)
Source: Transplantation Reviews - December 28, 2017 Category: Transplant Surgery Authors: S. Benjamens, S.P. Berger, A.W.J.M. Glaudemans, J.S.F. Sanders, R.A. Pol, R.H.J.A. Slart Tags: Review article Source Type: research
Circulating and urinary microRNAs as possible biomarkers in kidney transplantation
The invasive needle biopsy is currently the only established technique to distinguish between different types of kidney allograft damage and there is an urgent need for the development of reliable non-invasive methods for the timely recognition of upcoming rejection episodes. microRNAs (miRNAs) belong to a class of small non-coding RNAs that modulate physiological and pathological processes by regulating gene expression via post-transcriptional inhibition of target messenger RNAs (mRNAs). Recently, miRNAs were detected in remarkably stable forms in human body fluids and found to be involved in pathological processes that o...
Source: Transplantation Reviews - December 19, 2017 Category: Transplant Surgery Authors: No émi Janszky, Caner Süsal Source Type: research
Subscription Prices
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 7, 2017 Category: Transplant Surgery Source Type: research
Editorial Board
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 7, 2017 Category: Transplant Surgery Source Type: research
Table of Contents
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 7, 2017 Category: Transplant Surgery Source Type: research
Instructions for Authors
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 7, 2017 Category: Transplant Surgery Source Type: research
Previous Issue
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 7, 2017 Category: Transplant Surgery Source Type: research
Clinical impact of culture-positive preservation fluid on solid organ transplantation: A systematic review and meta-analysis
Contamination of the preservation fluid (PF) used for donated organs is a potential source of post-transplant infection. However, the information on this issue is scarce. We therefore conducted a systematic review and meta-analysis to assess the incidence of culture-positive PF and its impact on solid organ transplant (SOT) recipients. Seventeen studies were identified and included. The overall incidence of culture-positive PF was 37% (95% CI: 27% to 49%), and the incidence of PF-related infections among SOT recipients with PF cultures that grew pathogenic microorganisms was 10% (95% CI: 7% to 15%). (Source: Transplantation Reviews)
Source: Transplantation Reviews - December 5, 2017 Category: Transplant Surgery Authors: Isabel Oriol, N. Sab é, C. Tebé, M. Veroux, I.F.S.F. Boin, J. Carratalà Source Type: research
Clinical Impact of Culture-positive Preservation Fluid on Solid Organ Transplantation: A Systematic Review and Meta-analysis
Contamination of the preservation fluid (PF) used for donated organs is a potential source of post-transplant infection. However, the information on this issue is scarce. We therefore conducted a systematic review and meta-analysis to assess the incidence of culture-positive PF and its impact on solid organ transplant (SOT) recipients. Seventeen studies were identified and included. The overall incidence of culture-positive PF was 37% (95% CI: 27% to 49%), and the incidence of PF-related infections among SOT recipients with PF cultures that grew pathogenic microorganisms was 10% (95% CI: 7% to 15%). (Source: Transplantation Reviews)
Source: Transplantation Reviews - December 5, 2017 Category: Transplant Surgery Authors: Isabel Oriol, N. Sab é, C. Tebé, M. Veroux, I.F.S.F. Boin, J. Carratalà Tags: Review article Source Type: research
