Pathological Characterization of Spontaneous AA Amyloidosis in Microminipigs
This study demonstrates that microminipigs with wild-type SAA develop AA amyloidosis and presents the possibility that differences in the environment surrounding amyloid, such as SAP, may influence differences in the pathological phenotype.PMID:37873595 | DOI:10.1177/01926233231204019 (Source: Toxicologic Pathology)
Source: Toxicologic Pathology - October 24, 2023 Category: Pathology Authors: Misaki Inoue Shinya Miyazaki Natsumi Kobayashi Akihisa Kangawa Tomoaki Murakami Source Type: research
Pathological Characterization of Spontaneous AA Amyloidosis in Microminipigs
This study demonstrates that microminipigs with wild-type SAA develop AA amyloidosis and presents the possibility that differences in the environment surrounding amyloid, such as SAP, may influence differences in the pathological phenotype.PMID:37873595 | DOI:10.1177/01926233231204019 (Source: Toxicologic Pathology)
Source: Toxicologic Pathology - October 24, 2023 Category: Pathology Authors: Misaki Inoue Shinya Miyazaki Natsumi Kobayashi Akihisa Kangawa Tomoaki Murakami Source Type: research
Pathological Characterization of Spontaneous AA Amyloidosis in Microminipigs
This study demonstrates that microminipigs with wild-type SAA develop AA amyloidosis and presents the possibility that differences in the environment surrounding amyloid, such as SAP, may influence differences in the pathological phenotype.PMID:37873595 | DOI:10.1177/01926233231204019 (Source: Toxicologic Pathology)
Source: Toxicologic Pathology - October 24, 2023 Category: Pathology Authors: Misaki Inoue Shinya Miyazaki Natsumi Kobayashi Akihisa Kangawa Tomoaki Murakami Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy
This article reviews the presentation given at the 2023 annual meeting of the Society of Toxicologic Pathology (STP) on liver toxicity observed with adeno-associated viral vector (AAV) gene therapy. After decades as a therapeutic modality largely confined to the academic research environment, gene therapy has emerged in recent years as a rapidly expanding therapeutic approach in the biopharmaceutical industry with AAV as the most commonly used viral vector for gene delivery. This interest in the field of gene therapy by industry has been enhanced by the recent success of approved therapies for curing genetic diseases such ...
Source: Toxicologic Pathology - September 29, 2023 Category: Pathology Authors: Laurence O Whiteley Source Type: research
