"Women with severe postpartum hemorrhage have a decreased endogenous thrombin potential before delivery": Comment from Mishima et  al
J Thromb Haemost. 2024 Mar;22(3):877-878. doi: 10.1016/j.jtha.2023.11.026.NO ABSTRACTPMID:38417983 | DOI:10.1016/j.jtha.2023.11.026 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 28, 2024 Category: Hematology Authors: Yuko Mishima Amir L Butt Kenneth E Stewart Kenichi A Tanaka Source Type: research

"Women with severe postpartum hemorrhage have a decreased endogenous thrombin potential before delivery": reply
J Thromb Haemost. 2024 Mar;22(3):879-880. doi: 10.1016/j.jtha.2023.12.003.NO ABSTRACTPMID:38417984 | DOI:10.1016/j.jtha.2023.12.003 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 28, 2024 Category: Hematology Authors: Claire de Moreuil Yesim Dargaud Brigitte Pan-Petesch Source Type: research

"The portal vein in patients with cirrhosis is not an excessively inflammatory or hypercoagulable vascular bed, a prospective cohort study": comment from Liu et  al
J Thromb Haemost. 2024 Mar;22(3):881-883. doi: 10.1016/j.jtha.2023.11.029.NO ABSTRACTPMID:38417985 | DOI:10.1016/j.jtha.2023.11.029 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 28, 2024 Category: Hematology Authors: Guofeng Liu Xiaoze Wang Xuefeng Luo Source Type: research

"The portal vein in patients with cirrhosis is not an excessively inflammatory or hypercoagulable vascular bed, a prospective cohort study": reply
J Thromb Haemost. 2024 Mar;22(3):884-885. doi: 10.1016/j.jtha.2023.12.009.NO ABSTRACTPMID:38417986 | DOI:10.1016/j.jtha.2023.12.009 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 28, 2024 Category: Hematology Authors: Ellen G Driever Ton Lisman Source Type: research

"Guidance on the Critical Shortage of Sodium Citrate Coagulation Tubes for Hemostasis Testing": comment from Radi šić Biljak et al
J Thromb Haemost. 2024 Mar;22(3):886-888. doi: 10.1016/j.jtha.2023.11.028.NO ABSTRACTPMID:38417987 | DOI:10.1016/j.jtha.2023.11.028 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 28, 2024 Category: Hematology Authors: Vanja Radi šić Biljak Matea Tomas Ivana Lapi ć Source Type: research

Factor V variants in bleeding and thrombosis
Res Pract Thromb Haemost. 2024 Jan 26;8(1):102330. doi: 10.1016/j.rpth.2024.102330. eCollection 2024 Jan.ABSTRACTA state-of-the-art lecture titled "Factor V variants in bleeding and thrombosis" was presented at the International Society on Thrombosis and Haemostasis (ISTH) congress in 2023. Blood coagulation is a finely regulated cascade of enzymatic reactions culminating in thrombin formation and fibrin deposition at the site of injury. Factor V (FV) plays a central role in this process, as its activated form is an essential procoagulant cofactor in prothrombin activation. However, other molecular forms of FV act as antic...
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Adarsh K Mohapatra Alice M Todaro Elisabetta Castoldi Source Type: research

Should bleeding be a concern in antiphospholipid syndrome?
Res Pract Thromb Haemost. 2024 Jan 26;8(1):102328. doi: 10.1016/j.rpth.2024.102328. eCollection 2024 Jan.NO ABSTRACTPMID:38404938 | PMC:PMC10883817 | DOI:10.1016/j.rpth.2024.102328 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Fernanda A Orsi Source Type: research

Evaluation of the ability of commercial enzyme-linked immunosorbent assays to measure mouse tissue factor
CONCLUSION: Our results indicate that some commercial ELISAs can be used to measure mouse TF levels in cell lysates but they cannot detect TF in plasma or EVs from endotoxemic mice.PMID:38404939 | PMC:PMC10883813 | DOI:10.1016/j.rpth.2024.102325 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Ana T A Sachetto Nigel Mackman Source Type: research

Evidence that inositol 1,4,5-trisphosphate 3-kinase and inositol 1,3,4,5-tetrakisphosphate are negative regulators of platelet function
CONCLUSION: ITPK and IP4 are negative regulators of platelet function. IP4 regulation of PH domain-containing proteins may represent a pathway by which platelet activation may be controlled during thrombosis.PMID:38404940 | PMC:PMC10885593 | DOI:10.1016/j.rpth.2024.102326 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Kalwant S Authi Sabeeya Khan Jonathan M Gibbins Susan D Brain Source Type: research

Neutrophil-dependent hepatic platelet accumulation and liver injury revealed by acetaminophen dose-response studies
CONCLUSION: The results indicate a role of neutrophils in APAP-induced liver injury that is dependent on the APAP dose and suggest involvement of neutrophil-platelet interactions in promoting hepatic injury in experimental APAP-induced ALF.PMID:38404941 | PMC:PMC10883821 | DOI:10.1016/j.rpth.2024.102323 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Anthony Schulte Dafna J Groeneveld Zimu Wei Bianca Hazel Matthew P Bernard Lauren G Poole James P Luyendyk Source Type: research

Anticoagulation in atrial fibrillation and end-stage kidney disease on hemodialysis: a meta-analysis of randomized trials comparing direct oral anticoagulants with vitamin K antagonists
CONCLUSION: Orally administered activated factor X inhibitors carried a similar risk of bleeding and death when compared with VKAs in patients with NVAF undergoing chronic hemodialysis. Moreover, there was a trend towards a reduction of thromboembolic events or stroke in patients receiving DOACs.PMID:38404942 | PMC:PMC10885786 | DOI:10.1016/j.rpth.2024.102332 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Maximilian Tscharre Daniel Steiner David Mutschlechner Cihan Ay Thomas Gremmel Source Type: research

Primary prevention of venous thromboembolism for cancer patients in randomized controlled trials: a bibliographical analysis of funding and trial characteristics
CONCLUSION: There were few significant differences between trial characteristics, suggesting that the evidence from commercially sponsored trials investigating VTE prophylaxis in patients with cancer is unlikely to be subject to bias attributable to commercial sponsorship.PMID:38404943 | PMC:PMC10884502 | DOI:10.1016/j.rpth.2024.102315 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Lucy Zhao Jayhan Kherani Pei Ye Li Kevin Zhang Angelina Horta Christine Lin Allen Li Ali Eshaghpour Mark Andrew Crowther Source Type: research

Comparison of different algorithms for lupus anticoagulant detection: a single-center experience
CONCLUSION: All laboratory algorithms showed equivalent diagnostic performance. Establishing the best method of interpretation for each assay is recommended to improve LA detection performance.PMID:38404944 | PMC:PMC10885790 | DOI:10.1016/j.rpth.2024.102333 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Dollapak Apipongrat Rattapan Lamool Pasra Arnutti Chetana Ruangpratheep Wittawat Chantkran Source Type: research

Impact of adverse pregnancy outcomes on brain vascular health and cognition
Res Pract Thromb Haemost. 2024 Jan 30;8(1):102331. doi: 10.1016/j.rpth.2024.102331. eCollection 2024 Jan.ABSTRACTA State of the Art lecture titled "Impact of Adverse Pregnancy Outcomes on Brain Vascular Health and Cognition" was presented at the International Society on Thrombosis and Haemostasis Congress in 2023. Adverse pregnancy outcomes, encompassing conditions such as gestational hypertension, eclampsia, preeclampsia, preterm birth, fetal growth restriction, stillbirth, and gestational diabetes, may form part of an underrecognized pathway from early adulthood reproductive health factors to later-life vascular cognitiv...
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Katrin Wolfova Eliza C Miller Source Type: research

Is glycoprotein VI involved in contractual negotiations?
Res Pract Thromb Haemost. 2024 Jan 26;8(1):102329. doi: 10.1016/j.rpth.2024.102329. eCollection 2024 Jan.NO ABSTRACTPMID:38404946 | PMC:PMC10883811 | DOI:10.1016/j.rpth.2024.102329 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Simone A Brysland James I Hearn Elizabeth E Gardiner Source Type: research