Baseline and Time ‐Averaged Values Predicting Residual Renal Function Decline Rate in Japanese Peritoneal Dialysis Patients
Abstract
Residual renal function (RRF) is a strong prognostic factor of morbidity and mortality in patients undergoing peritoneal dialysis (PD). We determined predictors of the RRF rate of decline using both baseline values and time‐averaged ones. We retrospectively analyzed 94 patients being treated with PD at the Japanese Red Cross Medical Center. The decline rate of RRF was calculated by a diminution in the weekly renal Kt/V between the first and last follow up divided by follow‐up years. The mean follow‐up period was 2.28 years, and the mean decline rate of weekly renal Kt/V was 0.25 per year. A multivariate ana...
Source: Therapeutic Apheresis and Dialysis - October 1, 2017 Category: Hematology Authors: Kiyotaka Uchiyama, Akane Yanai, Keizo Maeda, Keisuke Ono, Kazuya Honda, Ryuji Tsujimoto, Yuka Kamijo, Mai Yanagi, Yoshitaka Ishibashi Tags: Original Article Source Type: research
Star Fruit Intoxication in a Patient Undergoing Regular Hemodialysis
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - October 1, 2017 Category: Hematology Authors: Jun ‐Li Tsai, Shang‐Feng Tsai Tags: Letter to the Editor Source Type: research
Impact of Statins on Arteriovenous Fistulas Outcomes: A Meta ‐Analysis
Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 67-72, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 28, 2017 Category: Hematology Source Type: research
Selection of DNA Aptamer That Blocks the Fibrillogenesis of a Proteolytic Amyloidogenic Fragment of β2m
Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 61-66, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 28, 2017 Category: Hematology Source Type: research
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Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 67-72, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 28, 2017 Category: Hematology Source Type: research
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Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 61-66, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 28, 2017 Category: Hematology Source Type: research
Adsorption of Nafamostat Mesilate on AN69ST Membranes: A Single ‐Center Retrospective and in vitro Study
This study retrospectively analyzed 87 continuous hemodiafiltration sessions in vivo. We divided the continuous hemodiafiltration sessions into AN69ST and non‐AN69ST groups using the nafamostat mesilate dose and activated clotting time as indicators of nafamostat mesilate adsorption onto the membrane. Furthermore, we studied the in vitro adsorption of nafamostat mesilate from nafamostat mesilate solutions onto four different hemodialysis membranes. This in vivo study shows that nafamostat mesilate doses were significantly higher, but activated clotting times were shorter (P < 0.001) in the AN69ST group than in the n...
Source: Therapeutic Apheresis and Dialysis - September 28, 2017 Category: Hematology Authors: Yoshihiko Nakamura, Shuuji Hara, Hiroki Hatomoto, Shintaro Yamasaki, Takafumi Nakano, Motoyasu Miyazaki, Norihiko Matsumoto, Yuhei Irie, Hiroyasu Ishikura Tags: Original Article Source Type: research
Selection of DNA Aptamer That Blocks the Fibrillogenesis of a Proteolytic Amyloidogenic Fragment of β2m
Abstract
Dialysis‐related amyloidosis (DRA) is a severe complication of hemodialysis that results in progressive destruction of bones and joints. Elevated concentrations of the β2‐microglobulin (β2m) level in the serum of subjects on hemodialysis promote the formation of amyloid fibrils in osteoarticular tissues. β2m lacking the N‐terminal six residues of the mature protein (ΔN6β2m) constitutes 25–30% of β2m in ex vivo DRA amyloid. Unlike full‐length wild‐type β2m, ΔN6β2m forms amyloid fibrils at neutral pH in vitro. However, the role of ΔN6β2m in DRA is, at present, poorly understood. In the present...
Source: Therapeutic Apheresis and Dialysis - September 28, 2017 Category: Hematology Authors: Kanon Fukasawa, Yuichiro Higashimoto, Yukio Ando, Yoshihiro Motomiya Tags: Original Article Source Type: research
Body Composition and Inflammation in Hemodialysis Patients
The objectives of the present study were to assess the body composition of patients on hemodialysis; to determine the concentrations of B‐type natriuretic peptide (BNP) in plasma and evaluate the association of BNP concentrations with volume overload; to determine the concentrations of C‐reactive protein (CRP), albumin and superoxide dismutase (SOD) activities as indicators of inflammatory or antioxidant processes. The study included 79 maintenance hemodialysis patients. Assessment of body compartments was carried out using a body composition monitor (BCM). After BCM measurements, blood samples were taken from the pati...
Source: Therapeutic Apheresis and Dialysis - September 22, 2017 Category: Hematology Authors: Ante Mandic, Ivan Cavar, Ivana Skoro, Ivan Tomic, Kristina Ljubic, Slavica Coric, Ivanka Mikulic, Igor Azinovic, Danijel Pravdic Tags: Original Article Source Type: research
Generalized Pustular Psoriasis With IL ‐36 Receptor Antagonist Mutation Successfully Treated With Granulocyte and Monocyte Adsorption Apheresis Accompanied by Reduced Serum IL‐6 Level
Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 92-93, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 15, 2017 Category: Hematology Source Type: research
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Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 92-93, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 15, 2017 Category: Hematology Source Type: research
Occult Hepatitis B Virus Infection With Increased Virus DNA Levels in a Chronic Hemodialysis Patient
Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 91-92, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 14, 2017 Category: Hematology Source Type: research
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Therapeutic Apheresis and Dialysis,Volume 22, Issue 1, Page 91-92, February 2018. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 14, 2017 Category: Hematology Source Type: research
Changing Trends in Therapeutic Plasmapheresis: An Indian Perspective
Abstract
Indications for therapeutic apheresis (TA) are dynamic; they keep changing and expanding because of introduction of newer treatment modalities and accumulating evidence in the form of case‐reports, case‐series and original articles. We evaluated our therapeutic plasmapheresis (TP) data and compared this data with an earlier published Indian report for indications, frequency, response rate and adverse reactions. We conducted a retrospective analysis of all TP procedures performed from January 2014 to June 2016 in department of Transfusion Medicine at a tertiary care hospital. All TP procedures performed for var...
Source: Therapeutic Apheresis and Dialysis - September 11, 2017 Category: Hematology Authors: Aseem K Tiwari, Gunjan Bhardwaj, Geet Aggarwal, Dinesh Arora, Ravi C Dara, Devi P Acharya, Sangeetha Gayam, Jui Choudhuri Tags: Original Article Source Type: research
Human Leukocyte Antigen Sensitization in Solid Organ Transplantation: A Primer on Terminology, Testing, and Clinical Significance for the Apheresis Practitioner
Abstract
The human leukocyte antigen (HLA) system is an important immunologic barrier that must be considered for successful solid organ transplantation. Formation of donor‐specific HLA antibodies in solid organ transplantation is an important cause of allograft injury and may contribute to recipient morbidity and mortality. Therapeutic plasma exchange is often requested to lower HLA antibody levels prior to or after transplantation and for management of HLA antibodies in the context of organ rejection. In this review, we summarize the current terminology, laboratory testing, and clinical significance of HLA sensitizatio...
Source: Therapeutic Apheresis and Dialysis - September 7, 2017 Category: Hematology Authors: Sarah Abbes, Ara Metjian, Alice Gray, Tereza Martinu, Laurie Snyder, Dong ‐feng Chen, Matthew Ellis, Gowthami M. Arepally, Oluwatoyosi Onwuemene Tags: Review Source Type: research
