Finite element analysis of biological soft tissue surrounded by a deformable membrane that controls transmembrane flow
Many biological soft tissues are hydrated porous hyperelastic materials, which consist of a complex solid skeleton with fine voids and fluid filling these voids. Mechanical interactions between the solid and t... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 23, 2018 Category: Biomedical Science Authors: Satoko Hirabayashi and Masami Iwamoto Tags: Research Source Type: research

Identification of influential proteins in the classical retinoic acid signaling pathway
In the classical pathway of retinoic acid (RA) mediated gene transcription, RA binds to a nuclear hormone receptor dimer composed of retinoic acid receptor (RAR) and retinoid X receptor (RXR), to induce the ex... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 16, 2018 Category: Biomedical Science Authors: Hamed Ghaffari and Linda R. Petzold Tags: Research Source Type: research

Numerical simulation of embryo transfer: how the viscosity of transferred medium affects the transport of embryos
Embryo transfer (ET) is a key step of assisted reproductive procedures, where the transferred medium containing the embryos is injected into the uterine cavity through a transcervical catheter and blended with... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 5, 2018 Category: Biomedical Science Authors: Dali Ding, Weiping Shi and Yang Shi Tags: Research Source Type: research

Osmotic and diffusive flows in single-file pores: new approach to modeling pore occupancy states
The relation between osmotic permeability, Pf, diffusion permeability, Pd, and the number of water molecules, Np, in the single-file membrane pore remains an open question. Theoretical analyses, empirical studies... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 1, 2018 Category: Biomedical Science Authors: Gordon Kepner Tags: Research Source Type: research

Modern and traditional approaches combined into an effective gray-box mathematical model of full-blood acid-base
The acidity of human body fluids, expressed by the pH, is physiologically regulated in a narrow range, which is required for the proper function of cellular metabolism. Acid-base disorders are common especiall... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - September 10, 2018 Category: Biomedical Science Authors: Filip Je žek and Jiří Kofránek Tags: Research Source Type: research

A conceptual model for optimizing vaccine coverage to reduce vector-borne infections in the presence of antibody-dependent enhancement
Many vector-borne diseases co-circulate, as the viruses from the same family are also transmitted by the same vector species. For example, Zika and dengue viruses belong to the same Flavivirus family and are prim... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - September 3, 2018 Category: Biomedical Science Authors: Biao Tang, Xi Huo, Yanni Xiao, Shigui Ruan and Jianhong Wu Tags: Research Source Type: research

Application of Bayesian evidence synthesis to modelling the effect of ketogenic therapy on survival of high grade glioma patients
Ketogenic therapy in the form of ketogenic diets or calorie restriction has been proposed as a metabolic treatment of high grade glioma (HGG) brain tumors based on mechanistic reasoning obtained mainly from an... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 20, 2018 Category: Biomedical Science Authors: Rainer J. Klement, Prasanta S. Bandyopadhyay, Colin E. Champ and Harald Walach Tags: Research Source Type: research

A mathematical model for Zika virus transmission dynamics with a time-dependent mosquito biting rate
Mathematical modeling has become a tool used to address many emerging diseases. One of the most basic and popular modeling frameworks is the compartmental model. Unfortunately, most of the available compartmen... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 1, 2018 Category: Biomedical Science Authors: Parinya Suparit, Anuwat Wiratsudakul and Charin Modchang Tags: Research Source Type: research

Determinants of viral load rebound on HIV/AIDS patients receiving antiretroviral therapy: results from South Africa
Antiretroviral therapy (ART) has become the standard of care for patients with HIV infection in South Africa and has led to the reduction in AIDS related morbidity and mortality. In developing countries, the n... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - July 16, 2018 Category: Biomedical Science Authors: Claris Shoko and Delson Chikobvu Tags: Research Source Type: research

Modeling the elevated risk of yellow fever among travelers visiting Brazil, 2018
Unlike the epidemic of yellow fever from 2016 to 17 in Brazil mostly restricted to the States of Minas Gerais and Espirito Santo, the epidemic from 2017 to 18 mainly involved S ão Paulo and Rio de Janeiro and r... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - July 2, 2018 Category: Biomedical Science Authors: Yohei Sakamoto, Takayuki Yamaguchi, Nao Yamamoto and Hiroshi Nishiura Tags: Research Source Type: research

A model of hematopoietic bone marrow apoptosis during growth factor deprivation in combination with a cytokine
The process by which blood cells are formed is referred to as hematopoiesis. This process involves a complex sequence of phases that blood cells must complete. During hematopoiesis, a small fraction of cells unde... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - June 21, 2018 Category: Biomedical Science Authors: Christina L. Mouser, Eliana S. Antoniou and Evros K. Vassiliou Tags: Research Source Type: research

Outside-host phage therapy as a biological control against environmental infectious diseases
Environmentally growing pathogens present an increasing threat for human health, wildlife and food production. Treating the hosts with antibiotics or parasitic bacteriophages fail to eliminate diseases that gr... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - June 8, 2018 Category: Biomedical Science Authors: Ilona Merikanto, Jouni T. Laakso and Veijo Kaitala Tags: Research Source Type: research

Modelling the impact of correlations between condom use and sexual contact pattern on the dynamics of sexually transmitted infections
It is believed that sexually active people, i.e. people having multiple or concurrent sexual partners, are at a high risk of sexually transmitted infections (STI), but they are likely to be more aware of the r... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - May 31, 2018 Category: Biomedical Science Authors: Nao Yamamoto, Keisuke Ejima and Hiroshi Nishiura Tags: Research Source Type: research

Numerical study of entrainment of the human circadian system and recovery by light treatment
While the effects of light as a zeitgeber are well known, the way the effects are modulated by features of the sleep-wake system still remains to be studied in detail. (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - May 9, 2018 Category: Biomedical Science Authors: Soon Ho Kim, Segun Goh, Kyungreem Han, Jong Won Kim and MooYoung Choi Tags: Research Source Type: research

On the suitability of an allometric proxy for nondestructive estimation of average leaf dry weight in eelgrass shoots I: sensitivity analysis and examination of the influences of data quality, analysis method, and sample size on precision
The effects of current anthropogenic influences on eelgrass (Zostera marina) meadows are noticeable. Eelgrass ecological services grant important benefits for mankind. Preservation of eelgrass meadows include sev... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - March 6, 2018 Category: Biomedical Science Authors: H éctor Echavarría-Heras, Cecilia Leal-Ramírez, Enrique Villa-Diharce and Nohe Cazarez-Castro Tags: Research Source Type: research