The impact of natural disasters on the spread of COVID-19: a geospatial, agent-based epidemiology model
Natural disasters and infectious diseases result in widespread disruption to human health and livelihood. At the scale of a global pandemic, the co-occurrence of natural disasters is inevitable. However, the i... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 3, 2021 Category: Biomedical Science Authors: Maximillian Van Wyk de Vries and Lekaashree Rambabu Tags: Research Source Type: research

The effect of men who have sex with men (MSM) on the spread of sexually transmitted infections
Sexually transmitted infections (STIs) have remained a worldwide public health threat. It is difficult to control the spread of STIs, not only because of heterogeneous sexual transmission between men and women... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 11, 2021 Category: Biomedical Science Authors: Hiromu Ito, Taro Yamamoto and Satoru Morita Tags: Research Source Type: research

Assessing countermeasures during a hepatitis A virus outbreak among men who have sex with men
In this study, we employ a parsimonious mathematical model to epidemiologically investigate the dynamics of infectio... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 11, 2021 Category: Biomedical Science Authors: Ryohei Saito, Akifumi Imamura and Hiroshi Nishiura Tags: Research Source Type: research

Analysis of international traveler mobility patterns in Tokyo to identify geographic foci of dengue fever risk
Travelers play a role in triggering epidemics of imported dengue fever because they can carry the virus to other countries during the incubation period. If a traveler carrying dengue virus visits open green sp... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 3, 2021 Category: Biomedical Science Authors: Baoyin Yuan, Hyojung Lee and Hiroshi Nishiura Tags: Research Source Type: research

On the relationship between inhibition and receptor occupancy by nondepolarizing neuromuscular blocking drugs
Nondepolarizing neuromuscular blocking drugs (NDNBs) are clinically used to produce muscle relaxation during general anesthesia. To better understand clinical properties of NDNBs, comparative in vitro pharmaco... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 21, 2021 Category: Biomedical Science Authors: Hikaru Hoshino and Eiko Furutani Tags: Research Source Type: research

Markov modelling of viral load adjusting for CD4 orthogonal variable and multivariate conditional autoregressive mapping of the HIV immunological outcomes among ART patients in Zimbabwe
This study aimed to jointly model HIV disease progression patterns based on viral load (VL) among adult ART patients adjusting for the time-varying “incremental transients states” variable, and the CD4 cell co... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 21, 2021 Category: Biomedical Science Authors: Zvifadzo Matsena Zingoni, Tobias F. Chirwa, Jim Todd and Eustasius Musenge Tags: Research Source Type: research

Modelling the impact of delaying vaccination against SARS-CoV-2 assuming unlimited vaccine supply
At the moment we have more than 177 million cases and 3.8 million deaths (as of June 2021) around the world and vaccination represents the only hope to control the pandemic. Imperfections in planning vaccine a... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - July 29, 2021 Category: Biomedical Science Authors: Marcos Amaku, Dimas Tadeu Covas, Francisco Antonio Bezerra Coutinho, Raymundo Soares Azevedo and Eduardo Massad Tags: Research Source Type: research

Estimating COVID-19 cases infected with the variant alpha (VOC 202012/01): an analysis of screening data in Tokyo, January-March 2021
In Japan, a part of confirmed patients ’ samples have been screened for the variant of concern (VOC), including the variant alpha with N501Y mutation. The present study aimed to estimate the actual number of ca... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - July 17, 2021 Category: Biomedical Science Authors: Hiroaki Murayama, Taishi Kayano and Hiroshi Nishiura Tags: Research Source Type: research

Exploring secondary SARS-CoV-2 transmission from asymptomatic cases using contact tracing data
Individuals with asymptomatic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can propagate the virus unknowingly and thus have been a focus of public health attentions since the early s... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - July 16, 2021 Category: Biomedical Science Authors: Ko Nakajo and Hiroshi Nishiura Tags: Research Source Type: research

How mathematical modeling could contribute to the quantification of metastatic tumor burden under therapy: insights in immunotherapeutic treatment of non-small cell lung cancer
Cancer is one of the leading death causes globally with about 8.2 million deaths per year and an increase in numbers in recent years. About 90% of cancer deaths do not occur due to primary tumors but due to me... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - June 2, 2021 Category: Biomedical Science Authors: Pirmin Schlicke, Christina Kuttler and Christian Schumann Tags: Research Source Type: research

Modelling the association between COVID-19 transmissibility and D614G substitution in SARS-CoV-2 spike protein: using the surveillance data in California as an example
The COVID-19 pandemic poses a serious threat to global health, and pathogenic mutations are a major challenge to disease control. We developed a statistical framework to explore the association between molecul... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - March 9, 2021 Category: Biomedical Science Authors: Shi Zhao, Jingzhi Lou, Lirong Cao, Hong Zheng, Marc K. C. Chong, Zigui Chen, Benny C. Y. Zee, Paul K. S. Chan and Maggie H. Wang Tags: Research Source Type: research

Correction to: Statistical field theory of the transmission of nerve impulses
An amendment to this paper has been published and can be accessed via the original article. (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - March 5, 2021 Category: Biomedical Science Authors: Gianluigi Zangari del Balzo Tags: Correction Source Type: research

A mathematical model of circadian rhythms and dopamine
The superchiasmatic nucleus (SCN) serves as the primary circadian (24hr) clock in mammals and is known to control important physiological functions such as the sleep-wake cycle, hormonal rhythms, and neurotran... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - February 17, 2021 Category: Biomedical Science Authors: Ruby Kim and Michael C. Reed Tags: Research Source Type: research

Reconstructing the household transmission of influenza in the suburbs of Tokyo based on clinical cases
Influenza is a public health issue that needs to be addressed strategically. The assessment of detailed infectious profiles is an important part of this effort. Household transmission data play a key role in e... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - February 10, 2021 Category: Biomedical Science Authors: Masaya M. Saito, Nobuo Hirotsu, Hiroka Hamada, Mio Takei, Keisuke Honda, Takamichi Baba, Takahiro Hasegawa and Yoshitake Kitanishi Tags: Research Source Type: research

Correction to: Required concentration index quantifies effective drug combinations against hepatitis C virus infection
An amendment to this paper has been published and can be accessed via the original article. (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - January 19, 2021 Category: Biomedical Science Authors: Yusuke Kakizoe, Yoshiki Koizumi, Yukino Ikoma, Hirofumi Ohashi, Takaji Wakita, Shingo Iwami and Koichi Watashi Tags: Correction Source Type: research