The World Journal of Biological Psychiatry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Assessing the impact of sex on high-frequency repetitive transcranial magnetic stimulation ´s clinical response in schizophrenia - results from a secondary analysis
Conclusion: In the largest rTMS trial on the treatment of SCZ negative symptoms we did not observe any significant effect of sex on treatment outcomes. Better assessments of sex-related differences could improve treatment individualization.PMID:38493362 | DOI:10.1080/15622975.2024.2327028 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Mattia Campana Thomas Schneider-Axmann Thomas Wobrock Berend Malchow Berthold Langguth Michael Landgrebe Peter Eichhammer Elmar Frank Joachim Cordes Wolfgang W ölwer Wolfgang Gaebel Georg Winterer G öran Hajak Christian Ohmann Pablo E Verde Marcella Rie Source Type: research

Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research

Lymphoblast transcriptome analysis in 22q11.2 deletion syndrome individuals with schizophrenia-spectrum disorder
Conclusions: Candidate pathways and upstream regulators may serve as novel biomarkers and treatment targets for SZ. Future transcriptome studies, including larger samples and proteomic analysis, are needed to substantiate our findings.PMID:38493364 | DOI:10.1080/15622975.2024.2327030 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Elena Michaelovsky Miri Carmel Doron Gothelf Abraham Weizman Source Type: research

Frequencies of < em > CYP2C19 < /em > and < em > CYP2D6 < /em > gene variants in a German inpatient sample with mood and anxiety disorders
CONCLUSION: There is a high prevalence of actionable PGx variants in psychiatric inpatients which may affect treatment response. Physicians should refer to PGx-informed dosing guidelines in carriers of these variants. Pre-emptive PGx testing in general may facilitate precision medicine also for other drugs metabolized by CYP2D6 and/or CYP2C19.PMID:38493365 | DOI:10.1080/15622975.2024.2321553 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Maike Scherf-Clavel Heike Weber Stefan Unterecker Daniel J M üller J ürgen Deckert Source Type: research

P300 Parameters in Major Depressive Disorder: A Systematic Review and Meta-Analysis
CONCLUSIONS: Decreased P300 amplitude may be a candidate diagnostic biomarker for MDD. However, prospective studies testing P300 amplitude as a monitoring biomarker for MDD are needed.PMID:38493361 | DOI:10.1080/15622975.2024.2321554 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Mehmet Kemal Ar ıkan Reyhan İlhan Özden Orhan Muhammed Taha Esmeray Şenol Turan Şakir Gica Hasan Bakay Oliver Pogarell K âşif Nevzat Tarhan Bar ış Metin Source Type: research

Corticosteroids and mania: A systematic review
CONCLUSION: Our findings suggest that mania is a common side-effect of corticosteroid use, particularly in prednisone equivalent doses above 40 mg. These findings hold practical significance for clinicians and provide insights into potential interventions, including careful monitoring, dose adjustments, and consideration of psychotropic medications when managing corticosteroid-induced mania.PMID:38363330 | DOI:10.1080/15622975.2024.2312572 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - February 16, 2024 Category: Psychiatry Authors: Mathias De Bock Pascal Sienaert Source Type: research