Clinical presentation, diagnostic findings, and outcome of adult horses with equine coronavirus infection at a veterinary teaching hospital: 33 cases (2012-2018)
Publication date: Available online 4 May 2019Source: The Veterinary JournalAuthor(s): E.H. Berryhill, K.G. Magdesian, M. Aleman, N. PusterlaAbstractEquine coronavirus (ECoV) is a recently described enteric virus with worldwide outbreaks; however, there are little data available on clinical presentation, diagnosis, and outcome. The study objective was to document case management of ECoV in adult horses presented to a referral hospital and compare to a cohort of horses that tested negative for ECoV. A retrospective case series was performed based on positive real-time quantitative PCR results for ECoV on faeces from horses t...
Source: The Veterinary Journal - May 5, 2019 Category: Veterinary Research Source Type: research

Warmblood Fragile Foal Syndrome causative single nucleotide polymorphism frequency in Warmblood horses in Brazil
This study highlights the importance of control measures to prevent an increase in the incidence of WFFS in Warmblood horses worldwide. (Source: The Veterinary Journal)
Source: The Veterinary Journal - May 5, 2019 Category: Veterinary Research Source Type: research

Cine balanced fast field echo magnetic resonance imaging of canine spinal arachnoid diverticulae pulsation
Publication date: Available online 2 May 2019Source: The Veterinary JournalAuthor(s): S.K. Shivapour, H.A. Volk, V. Watts, S. De DeckerAbstractCanine spinal arachnoid diverticulae (SAD) are characterised by focal cerebrospinal fluid dilatations within the subarachnoid space, most commonly associated with nonpainful paresis and ataxia secondary to chronic compressive myelopathy. Numerous imaging techniques have been described for diagnosis of this condition, including myelography, computed tomography myelography, and magnetic resonance imaging (MRI). The present retrospective study investigated the utility of cine balanced ...
Source: The Veterinary Journal - May 4, 2019 Category: Veterinary Research Source Type: research

Potential dietary feed additives with antibacterial effects and their impact on performance of weaned piglets: A meta-analysis
Publication date: Available online 1 May 2019Source: The Veterinary JournalAuthor(s): W. Vanrolleghem, S. Tanghe, S. Verstringe, G. Bruggeman, D. Papadopoulos, P. Trevisi, J. Zentek, S. Sarrazin, J. DewulfAbstractThis meta-analysis evaluated the use of potential dietary feed additives (pDFA) with antibacterial effects and their impact on the perfomance of weaned piglets. Twenty-three peer-reviewed in vivo studies, comprising 50 trials, were identified between January 2010 and January 2017. The pDFA in these studies could be grouped in 5 classes: antimicrobial peptides, chitosan, lysozyme, medium chain fatty acids/ triglyce...
Source: The Veterinary Journal - May 2, 2019 Category: Veterinary Research Source Type: research

Comparison of Finnish meat inspection records and average daily gain for cattle herds differing in Mycoplasma bovis test-status
The objectives of this study were: (1) to determine whether meat inspection records can aid identification of cattle farms supporting M. bovis infection, and (2) to compare the average daily weight gain estimated from carcass weight for cattle originating from farms differing in M. bovis test-status. Meat inspection records were collected from two abattoirs in 2015; 80 677 animals in total. All the dairy and mixed breed cows and bulls used for meat production were categorized according to known M. bovis infection status of the farms from which the cattle were derived; positive, contact or control farms. The associations be...
Source: The Veterinary Journal - May 2, 2019 Category: Veterinary Research Source Type: research

Relationship between haematological profile and progression or spontaneous regression of melanoma in melanoma-bearing Libechov minipigs
Publication date: Available online 1 May 2019Source: The Veterinary JournalAuthor(s): J. Čížková, M. Erbanová, J. Sochor, A. Jindrová, K. Strnadová, V. HorákAbstractHaematological parameters, plasma iron concentration, and bodyweight were monitored in Melanoma-bearing Libechov Minipigs (MeLiM) from 5-18 weeks old. Animals with melanoma progression (P group) and spontaneous regression (SR group) were compared.The P group showed the lowest median values of red blood cell counts (RBC), haematocrit (HCT), haemoglobin concentration (HGB), and bodyweight, whereas the control white (tumour-free) pigs (C group) revealed th...
Source: The Veterinary Journal - May 2, 2019 Category: Veterinary Research Source Type: research

Genetic screening for cerebellar abiotrophy, severe combined immunodeficiency and lavender foal syndrome in Arabian horses in Poland
Publication date: Available online 27 April 2019Source: The Veterinary JournalAuthor(s): Monika Bugno-Poniewierska, Monika Stefaniuk-Szmukier, Agata Piestrzyńska -Kajtoch, Agnieszka Fornal, Katarzyna Piórkowska, Katarzyna Ropka-MolikAbstractThe highly selective breeding of Arabian horses results in inbreeding depression and genetic disorders, thereby causing significant economic loss. The Polish population of Arabians has a great impact on many breeding programmes. The aim of the current study was to monitor genetic variants involved in the most common genetic disorders of this breed. A total of 808 elite Arabian horses ...
Source: The Veterinary Journal - April 28, 2019 Category: Veterinary Research Source Type: research

Epidemiology of massive hepatocellular carcinoma in dogs: A 4-Year retrospective study
The objective of this study was to investigate the clinical features and risk factors for canine HCC. Medical records of 44 dogs diagnosed with HCC at Hokkaido University Veterinary Teaching Hospital between 2013 and 2017 were retrospectively reviewed. All dogs evaluated at the teaching hospital during the study period were used as the reference population for breed, age, sex predispositions or possible related factors for HCC, including concurrent disorders. Clinical characteristics of HCC were determined using propensity score matching analysis.The prevalence of HCC diagnosis was 0.96%. Multivariate analysis revealed tha...
Source: The Veterinary Journal - April 25, 2019 Category: Veterinary Research Source Type: research

Questions associated with the development of novel drugs intended for the treatment of bacterial infections in veterinary species
Publication date: Available online 20 April 2019Source: The Veterinary JournalAuthor(s): Marilyn N. Martinez, Jeffrey L. Watts, Jeffrey M. GilbertAbstractThe emergence of multi-drug resistant bacteria has limited therapeutic options for the treatment of bacterial diseases in both human and veterinary medicine. This has resulted in an urgent need for novel agents to treat infectious diseases. Veterinary medicine is further constrained by the need to ensure that our emerging therapeutics have minimal or no impact on resistance in human pathogens. Thus, there has recently been increased attention given to the development of a...
Source: The Veterinary Journal - April 22, 2019 Category: Veterinary Research Source Type: research

Could polymorphisms in ABCB1 gene represent a genetic risk factor for the development of mammary tumors in dogs?
In this study, we performed PCR and direct sequencing of ABCB1 exons 9 and 26 in 47 tissue DNA samples from canine mammary tumors.A statistically significant correlation between distinct canine breeds and the frequency of ABCB1 polymorphisms (c.985T > A and c.3442A > G SNP in ABCB1exons 9 and 26, respectively) was observed (P = 0.0015). In contrast, the TNM clinical staging, age, histological type and grade, as well as other histopathological characteristics, did not present statistically significant difference in relation to one or both SNP found in exons 9 and 26. These findings raise questions about the role...
Source: The Veterinary Journal - April 22, 2019 Category: Veterinary Research Source Type: research

Increased p16CDKN2A, but not p53, immunostaining is predictive of longer survival time in cats with oral squamous cell carcinomas
This study used 52 feline oral SCCs to determine if prognosis can be predicted by the age or sex of the cat, the presence of bone within the diagnostic sample, or the anatomic location of the SCC. Additionally, as p16CDKN2A protein (p16) and p53 are prognostic for human oral SCCs, p16 and p53 immunostaining was evaluated.Only SCC location and p16 immunostaining were prognostic. Cats with oropharyngeal SCCs had an estimated median survival time (MST) of 151 days which was significantly longer than cats with maxillary (51 days P = 0.017), sublingual (33 days P = 0.011) and mandibular (34 days P = 0.029) SCCs. Ove...
Source: The Veterinary Journal - April 20, 2019 Category: Veterinary Research Source Type: research

Airborne particulate size and concentrations in five Thoroughbred training yards in Newmarket (UK)
This study documents airborne particulate size and concentrations in Newmarket training yards using a nephelometer (DustTrak DRX 8534, TSI). Each stall was sampled on a summer and winter day at three time points (morning, midday and evening). Minimum, mean and maximum/min ranges were calculated for the fraction of particulates with an aerodynamic diameter smaller than 2.5 µm (particulate matter (PM) 2.5) and 10 µm (PM10). Comparisons were made using Wilcoxon signed-rank test. Average particulate concentration ranges were 0.02-0.27 (summer) mg/m3, 0.01-0.37 (winter) mg/m3 for PM2.5 and 0.02-0.39 (summer) mg/m3, 0.02-0...
Source: The Veterinary Journal - April 11, 2019 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: May 2019Source: The Veterinary Journal, Volume 247Author(s): (Source: The Veterinary Journal)
Source: The Veterinary Journal - April 8, 2019 Category: Veterinary Research Source Type: research

Prevalence of excessive negative energy balance in commercial United Kingdom dairy herds
The objectives of this study were to determine the individual animal and herd level prevalence of excessive negative energy balance (eNEB) in commercial UK dairy herds. Between April 2006 and March 2015, blood samples from 84,369 individual cows from 1,748 different UK farms were received by a commercial laboratory service specializing in dairy cow nutritional monitoring. Following removal of all potential duplicate cows, the final dataset comprised 69,161 unique individual cows. The prevalence of eNEB was determined using plasma thresholds of β-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA) and glucose.Overall ...
Source: The Veterinary Journal - April 7, 2019 Category: Veterinary Research Source Type: research

Enterococcus infections in foals
Publication date: Available online 6 April 2019Source: The Veterinary JournalAuthor(s): A.T. Willis, K.G. Magdesian, B.A. Byrne, J.M. EdmanAbstractEnterococci have been increasing in prevalence in foal sepsis over the past three decades. There are no published studies in the peer-reviewed literature documenting common sites of infection, antimicrobial susceptibility, or outcome specifically associated with enterococcal infections in foals. Our objectives were to evaluate the sites of origin, antimicrobial susceptibility, and survival outcome to discharge in foals with enterococcal infections compared with foals with sepsis...
Source: The Veterinary Journal - April 7, 2019 Category: Veterinary Research Source Type: research