A Single-Center Experience of Correlation of Pulse Pressure to Mortality of Stroke Hemorrhage Patients in Indonesia
CONCLUSION: Pulse pressure had an impact on the mortality of patients with acute hemorrhagic stroke.PMID:37593547 | PMC:PMC10432090 | DOI:10.1155/2023/5517493 (Source: The Scientific World Journal)
Source: The Scientific World Journal - August 18, 2023 Category: Science Authors: Feda Anisah Makkiyah Saraah Dicha Rahmah Hida Nurrizzka Source Type: research

Computational Identification of Most Deleterious Missense Mutations in Human PD-1 Gene
In conclusion, the comprehensive screening process undertaken in this study has successfully identified R38C, D61V, R94C, and D117V as the primary mutations contributing to genetic cancer progression and immunotherapeutic resistance against PD-1 blockers. The integration of protein topology analysis, structural alignment, docking studies with PD-L1, and assessment of protein flexibility have collectively provided robust evidence to support the pathogenic significance of these mutations.PMID:37583448 | PMC:PMC10425257 | DOI:10.1155/2023/4360203 (Source: The Scientific World Journal)
Source: The Scientific World Journal - August 16, 2023 Category: Science Authors: Haitham Ahmed Al-Madhagi Source Type: research