Propranolol use in patients with cirrhosis and refractory ascites: A nationwide study
Conclusions: Use of propanolol was associated with reduced mortality, compared with controls, in this nationwide cohort of patients with cirrhosis and refractory ascites. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 16, 2022 Category: Gastroenterology Authors: Yen-Chun Chen Yun-Da Li Chia-Ming Lu Wei-Chun Huang Sung-Shuo Kao Wen-Chi Chen Source Type: research

Saudi association for the study of liver diseases and transplantation position statement on the hepatology workforce in Saudi Arabia
Bandar Al-Judaibi, M Katherine Dokus, Waleed Al-hamoudi, Dieter Broering, Mohammad Mawardi, Nasser AlMasri, Mohammed Aljawad, Ibrahim H Altraif, Faisal Abaalkhail, Saleh A AlqahtaniSaudi Journal of Gastroenterology 2022 28(2):101-107 The field of hepatology has evolved significantly over the last two decades. Hepatology practice in Saudi Arabia (SA) was dominated by hepatitis B and C viruses but is now being overtaken by patients with non-alcoholic fatty liver disease. These patients require greater medical attention as their care is more complex compared to patients with viral hepatitis. In addition, liver transplantatio...
Source: The Saudi Journal of Gastroenterology - March 16, 2022 Category: Gastroenterology Authors: Bandar Al-Judaibi M Katherine Dokus Waleed Al-hamoudi Dieter Broering Mohammad Mawardi Nasser AlMasri Mohammed Aljawad Ibrahim H Altraif Faisal Abaalkhail Saleh A Alqahtani Source Type: research

Association of metabolic traits with occurrence of nonalcoholic fatty liver disease-related hepatocellular carcinoma: A systematic review and meta-analysis of longitudinal cohort studies
Conclusion: DM and overweight/obesity are high risk factors for NAFLD-related HCC. In particular, DM increases 4-fold the risk of HCC incidence in NAFLD patients with advanced fibrosis/cirrhosis. There is a need to strengthen surveillance for HCC in NAFLD patients with DM, especially in those with advanced fibrosis/cirrhosis. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 16, 2022 Category: Gastroenterology Authors: Jin Chen Shu Song Xiangsu Li Dongxue Bian Xudong Wu Source Type: research

N-acetylcysteine for non-acetaminophen induced acute liver failure: A review
Shirley Xue Jiang, Trana Hussaini, Eric M. YoshidaSaudi Journal of Gastroenterology 2022 28(2):85-91 The use of N-acetylcysteine (NAC) for non-acetaminophen-induced acute liver failure (NAI-ALF) has been increasing despite controversy in its efficacy. National guidelines are in disagreement for NAC use as standard of care; however, many healthcare centers continue to adopt the use of NAC outside of acetaminophen poisoning. While NAC may have multiple mechanisms of action in treatment of ALF, this has not translated to clinical benefit. Murine models have reported antioxidant and anti-inflammatory properties, as well as im...
Source: The Saudi Journal of Gastroenterology - March 16, 2022 Category: Gastroenterology Authors: Shirley Xue Jiang Trana Hussaini Eric M. Yoshida Source Type: research

Beta-blocker therapy in refractory ascites: A steady march towards the truth
Nicholas Bartell, Bandar Al-JudaibiSaudi Journal of Gastroenterology 2022 28(2):83-84 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 16, 2022 Category: Gastroenterology Authors: Nicholas Bartell Bandar Al-Judaibi Source Type: research

Letter to the editor regarding & #8220;The efficacy and safety of infliximab and calcineurin inhibitors in steroid-refractory UC patients: A meta-analysis & #8221;
Qingcheng Zhu, Dingyu TanSaudi Journal of Gastroenterology 2022 28(1):81-82 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Qingcheng Zhu Dingyu Tan Source Type: research

A few comments about the evaluation for small and diminutive colorectal polyps in end-stage renal disease patients
Tiantian Lei, Hongsheng MaSaudi Journal of Gastroenterology 2022 28(1):80-80 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Tiantian Lei Hongsheng Ma Source Type: research

Peroral endoscopic myotomy (POEM) for the treatment of achalasia: A multicenter Middle Eastern experience
Conclusions: POEM is a promising procedure for the treatment of achalasia with a high clinical success rate, short hospital admission, and a reassuring safety profile. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Abed Al Lehibi Shaimaa Elkholy Mohamed Gouda Ammar Al Dabbagh Areej Al Balkhi Abdullah Almtawa Nawwaf Al Otaibi Mohammed El-Sherbiny Kareem Essam Mohammed Attieh Alzahrani Ahmed Al Ghamdi Adel Al Ghamdi Ahmad AlEid Adel Qutub Abdulrahman Alamr Shameem Ahm Source Type: research

Comparison of cold snare polypectomy and endoscopic mucosal resection for 3 & #8211;10-mm colorectal polyps in end-stage renal disease patients
Conclusions: There were no differences between the CSP and EMR group in terms of efficacy and safety. CSP can be one of the standard methods for the removal of 3–10-mm-sized colorectal polyps in patients with ESRD. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Chang Kyo Oh Ho Soon Choi Young-Seok Cho Source Type: research

Is the nuclear factor kappa-b (NF- & #954;B) pathway and inflammatory status associated with colorectal cancer ?
Conclusion: Inflammatory status and reduced dietary antioxidant capacity are risk factors in the development of colorectal cancer. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: B & #252; & #351;ra Atabilen Gamze Akbulut Merve Bacanli Do & #287;an Uncu Source Type: research

Continuous infusion of lidocaine in pediatric colonoscopy: A randomized double-blind placebo-controlled study
Conclusion: Continuous infusion of lidocaine resulted in reduction of propofol and sufentanil requirements, recovery time, and risk of hypoxemia during pediatric colonoscopy. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Chao Yuan Chengli Wang Jiayao Wu Ningyang Gao Kunwei Li Yongle Li Xizhao Huang Wei Huang Zurong Hu Source Type: research

Comparison of channel sampling methods and brush heads in surveillance culture of endoscope reprocessing: A propensity score matching and paired study
Conclusion: FBFSM was confirmed to be a more sensitive sampling technique. PU and PA brushes had no significant difference in sampling effect. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Xue-Yue Ji Pei-Yong Ning Chun-Nan Fei Jia Song Xue-Mei Dou Nan-Nan Zhang Jun Liu He Liu Source Type: research

Water immersion sigmoidoscopy versus standard insufflation for colorectal cancer screening: A cohort study
Conclusions: WIS does not ameliorate tolerance to and quality of sigmoidoscopy screening measured by several scores. When offered a choice, the women's willingness to repeat WIS or CO2S without sedation was poor and raises concern on the opportunity of screening sigmoidoscopy without sedation in these subjects. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Calcedonio Calcara Paolo Aseni Keith Siau Pietro Gambitta Sergio Cadoni Source Type: research

Development and validation of a predictive model for feeding intolerance in intensive care unit patients with sepsis
Conclusions: The new prediction model based on deep learning can effectively predict enteral feeding intolerance in intensive care unit patients with sepsis. Simple clinical information such as infection site, nutrient type, and septic shock can be useful in stratifying a septic patient's risk of EN intolerance. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Kunlin Hu Xin lei Deng Lin Han Shulin Xiang Bin Xiong Liao Pinhu Source Type: research

Wilson disease in children and young adults - State of the art
Atchariya Chanpong, Anil DhawanSaudi Journal of Gastroenterology 2022 28(1):21-31 Wilson disease (WD) is an autosomal recessive disorder caused by mutations of the ATP7B gene, with a reported prevalence of 1:30,000–50,000. ATP7B encodes an enzyme called transmembrane copper-transporting ATPase, which is essential for copper incorporation into ceruloplasmin and for copper excretion into the bile. A lack or dysfunction of this enzyme results in a progressive accumulation of copper in several organs, especially in the liver, the nervous system, corneas, kidneys, and heart. Children with WD can present with asymp...
Source: The Saudi Journal of Gastroenterology - February 4, 2022 Category: Gastroenterology Authors: Atchariya Chanpong Anil Dhawan Source Type: research