Pipeline: Ocular biostatistics: Which is better: One or two?
Ocul Surf. 2023 Nov 21:S1542-0124(23)00140-4. doi: 10.1016/j.jtos.2023.11.006. Online ahead of print.NO ABSTRACTPMID:37995837 | DOI:10.1016/j.jtos.2023.11.006 (Source: The Ocular Surface)
Source: The Ocular Surface - November 23, 2023 Category: Opthalmology Authors: Gary D Novack Source Type: research

Pipeline: Ocular biostatistics: Which is better: One or two?
Ocul Surf. 2023 Nov 21:S1542-0124(23)00140-4. doi: 10.1016/j.jtos.2023.11.006. Online ahead of print.NO ABSTRACTPMID:37995837 | DOI:10.1016/j.jtos.2023.11.006 (Source: The Ocular Surface)
Source: The Ocular Surface - November 23, 2023 Category: Opthalmology Authors: Gary D Novack Source Type: research

Pipeline: Ocular biostatistics: Which is better: One or two?
Ocul Surf. 2023 Nov 21:S1542-0124(23)00140-4. doi: 10.1016/j.jtos.2023.11.006. Online ahead of print.NO ABSTRACTPMID:37995837 | DOI:10.1016/j.jtos.2023.11.006 (Source: The Ocular Surface)
Source: The Ocular Surface - November 23, 2023 Category: Opthalmology Authors: Gary D Novack Source Type: research

Pipeline: Ocular biostatistics: Which is better: One or two?
Ocul Surf. 2023 Nov 21:S1542-0124(23)00140-4. doi: 10.1016/j.jtos.2023.11.006. Online ahead of print.NO ABSTRACTPMID:37995837 | DOI:10.1016/j.jtos.2023.11.006 (Source: The Ocular Surface)
Source: The Ocular Surface - November 23, 2023 Category: Opthalmology Authors: Gary D Novack Source Type: research

A new treatment changes the game: An innovative management of a child suffering from severe ligneous conjunctivitis with type 1 plasminogen deficiency
Ocul Surf. 2023 Nov 20:S1542-0124(23)00135-0. doi: 10.1016/j.jtos.2023.11.001. Online ahead of print.NO ABSTRACTPMID:37992996 | DOI:10.1016/j.jtos.2023.11.001 (Source: The Ocular Surface)
Source: The Ocular Surface - November 22, 2023 Category: Opthalmology Authors: M Desira E Gabison P V Jacomet D Denis F Dalmas T David A Aziz Source Type: research

A new treatment changes the game: An innovative management of a child suffering from severe ligneous conjunctivitis with type 1 plasminogen deficiency
Ocul Surf. 2023 Nov 20:S1542-0124(23)00135-0. doi: 10.1016/j.jtos.2023.11.001. Online ahead of print.NO ABSTRACTPMID:37992996 | DOI:10.1016/j.jtos.2023.11.001 (Source: The Ocular Surface)
Source: The Ocular Surface - November 22, 2023 Category: Opthalmology Authors: M Desira E Gabison P V Jacomet D Denis F Dalmas T David A Aziz Source Type: research

Corneal neuroepithelial compartmentalized microfluidic chip model for evaluation of toxicity-induced dry eye
Ocul Surf. 2023 Nov 18:S1542-0124(23)00138-6. doi: 10.1016/j.jtos.2023.11.004. Online ahead of print.ABSTRACTPart of the lacrimal functional unit, the cornea protects the ocular surface from numerous environmental aggressions and xenobiotics. Toxicological evaluation of compounds remains a challenge due to complex interactions between corneal nerve endings and epithelial cells. To this day, models do not integrate the physiological specificity of corneal nerve endings and are insufficient for the detection of low toxic effects essential to anticipate Toxicity-Induced Dry Eye (TIDE). Using high-content imaging tool, we here...
Source: The Ocular Surface - November 20, 2023 Category: Opthalmology Authors: No émie Bonneau Ana ïs Potey Michael-Adrien Vitoux Romain Magny Camille Guerin Christophe Baudouin Jean-Michel Peyrin Fran çoise Brignole-Baudouin Annabelle R éaux-Le Goazigo Source Type: research

Corneal neuroepithelial compartmentalized microfluidic chip model for evaluation of toxicity-induced dry eye
Ocul Surf. 2023 Nov 18:S1542-0124(23)00138-6. doi: 10.1016/j.jtos.2023.11.004. Online ahead of print.ABSTRACTPart of the lacrimal functional unit, the cornea protects the ocular surface from numerous environmental aggressions and xenobiotics. Toxicological evaluation of compounds remains a challenge due to complex interactions between corneal nerve endings and epithelial cells. To this day, models do not integrate the physiological specificity of corneal nerve endings and are insufficient for the detection of low toxic effects essential to anticipate Toxicity-Induced Dry Eye (TIDE). Using high-content imaging tool, we here...
Source: The Ocular Surface - November 20, 2023 Category: Opthalmology Authors: No émie Bonneau Ana ïs Potey Michael-Adrien Vitoux Romain Magny Camille Guerin Christophe Baudouin Jean-Michel Peyrin Fran çoise Brignole-Baudouin Annabelle R éaux-Le Goazigo Source Type: research

Recent advances in age-related meibomian gland dysfunction (ARMGD)
Ocul Surf. 2023 Nov 16:S1542-0124(23)00137-4. doi: 10.1016/j.jtos.2023.11.003. Online ahead of print.ABSTRACTMeibomian glands (MGs), located within the tarsal plate of the eyelid, secrete meibum which is the lipid-rich secretion necessary for stabilizing the tear film and preventing tear evaporation. Changes in the quality and quantity of meibum produced causes MG dysfunction (MGD), the leading cause of evaporative dry eye disease (EDED). MGD is an underdiagnosed disease and it is estimated that, in the US, approximately 70 % of the population over 60 have MGD. Three forms of MGD occur based on their meibum secretion: hypo...
Source: The Ocular Surface - November 18, 2023 Category: Opthalmology Authors: Isabel Moreno Sudhir Verma Tarsis Ferreira Gesteira Vivien J Coulson-Thomas Source Type: research

Recent advances in age-related meibomian gland dysfunction (ARMGD)
Ocul Surf. 2023 Nov 16:S1542-0124(23)00137-4. doi: 10.1016/j.jtos.2023.11.003. Online ahead of print.ABSTRACTMeibomian glands (MGs), located within the tarsal plate of the eyelid, secrete meibum which is the lipid-rich secretion necessary for stabilizing the tear film and preventing tear evaporation. Changes in the quality and quantity of meibum produced causes MG dysfunction (MGD), the leading cause of evaporative dry eye disease (EDED). MGD is an underdiagnosed disease and it is estimated that, in the US, approximately 70 % of the population over 60 have MGD. Three forms of MGD occur based on their meibum secretion: hypo...
Source: The Ocular Surface - November 18, 2023 Category: Opthalmology Authors: Isabel Moreno Sudhir Verma Tarsis Ferreira Gesteira Vivien J Coulson-Thomas Source Type: research

Impaired healing in an incision wound in corneal stroma in a lumican-null mouse
CONCLUSION: Loss of lumican perturbs the healing of penetrating incision in mouse corneal stroma in association with suppression of myofibroblast generation.PMID:37972853 | DOI:10.1016/j.jtos.2023.11.002 (Source: The Ocular Surface)
Source: The Ocular Surface - November 16, 2023 Category: Opthalmology Authors: Eimi Suzuki Takayoshi Sumioka Shizuya Saika Masayasu Miyajima Shingo Yasuda Hiroki Iwanishi Yukihisa Takada Kana Ichikawa Jhuwala Venkatakrishnan Chia-Yang Liu Winston Whei-Yang Kao Yuka Okada Source Type: research

Impaired healing in an incision wound in corneal stroma in a lumican-null mouse
CONCLUSION: Loss of lumican perturbs the healing of penetrating incision in mouse corneal stroma in association with suppression of myofibroblast generation.PMID:37972853 | DOI:10.1016/j.jtos.2023.11.002 (Source: The Ocular Surface)
Source: The Ocular Surface - November 16, 2023 Category: Opthalmology Authors: Eimi Suzuki Takayoshi Sumioka Shizuya Saika Masayasu Miyajima Shingo Yasuda Hiroki Iwanishi Yukihisa Takada Kana Ichikawa Jhuwala Venkatakrishnan Chia-Yang Liu Winston Whei-Yang Kao Yuka Okada Source Type: research

Impaired healing in an incision wound in corneal stroma in a lumican-null mouse
CONCLUSION: Loss of lumican perturbs the healing of penetrating incision in mouse corneal stroma in association with suppression of myofibroblast generation.PMID:37972853 | DOI:10.1016/j.jtos.2023.11.002 (Source: The Ocular Surface)
Source: The Ocular Surface - November 16, 2023 Category: Opthalmology Authors: Eimi Suzuki Takayoshi Sumioka Shizuya Saika Masayasu Miyajima Shingo Yasuda Hiroki Iwanishi Yukihisa Takada Kana Ichikawa Jhuwala Venkatakrishnan Chia-Yang Liu Winston Whei-Yang Kao Yuka Okada Source Type: research

Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels
Ocul Surf. 2023 Nov 6:S1542-0124(23)00134-9. doi: 10.1016/j.jtos.2023.10.003. Online ahead of print.NO ABSTRACTPMID:37939847 | DOI:10.1016/j.jtos.2023.10.003 (Source: The Ocular Surface)
Source: The Ocular Surface - November 8, 2023 Category: Opthalmology Authors: Alessandro Lambiase Fabiana Mallone Marta Sacchetti Marco Segatto Mayra Colardo Valerio Di Martino Alice Bruscolini Source Type: research

Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels
Ocul Surf. 2023 Nov 6:S1542-0124(23)00134-9. doi: 10.1016/j.jtos.2023.10.003. Online ahead of print.NO ABSTRACTPMID:37939847 | DOI:10.1016/j.jtos.2023.10.003 (Source: The Ocular Surface)
Source: The Ocular Surface - November 8, 2023 Category: Opthalmology Authors: Alessandro Lambiase Fabiana Mallone Marta Sacchetti Marco Segatto Mayra Colardo Valerio Di Martino Alice Bruscolini Source Type: research