[Articles] The global burden of scabies: a cross-sectional analysis from the Global Burden of Disease Study 2015
The burden of scabies is greater in tropical regions, especially in children, adolescents, and elderly people. As a worldwide epidemiological assessment, GBD 2015 provides broad and frequently updated measures of scabies burden in terms of skin effects. These global data might help guide research protocols and prioritisation efforts and focus scabies treatment and control measures. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - September 20, 2017 Category: Infectious Diseases Authors: Chante Karimkhani, Danny V Colombara, Aaron M Drucker, Scott A Norton, Roderick Hay, Daniel Engelman, Andrew Steer, Margot Whitfeld, Mohsen Naghavi, Robert P Dellavalle Tags: Articles Source Type: research

[Comment] Scratching the itch: is scabies a truly neglected disease?
Human scabies is a parasitic skin disease that affects people worldwide. To improve public-health decision making, measurement of the global burden of scabies is key. In this issue of The Lancet Infectious Diseases, Chante Karimkhani and colleagues1 report a cross-sectional analysis of the Global Burden of Disease (GBD) 2015 big data to show a robust estimate of the extent and impact of this ubiquitous mite on human health.1 The GBD project is an international collaboration of experts from 30 countries. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - September 20, 2017 Category: Infectious Diseases Authors: Olivier Chosidow, L Claire Fuller Tags: Comment Source Type: research

[Articles] Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study
Xpert Ultra detected significantly more tuberculous meningitis than did either Xpert or culture. WHO now recommends the use of Xpert Ultra as the initial diagnostic test for suspected tuberculous meningitis. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - September 14, 2017 Category: Infectious Diseases Authors: Nathan C Bahr, Edwin Nuwagira, Emily E Evans, Fiona V Cresswell, Philip V Bystrom, Adolf Byamukama, Sarah C Bridge, Ananta S Bangdiwala, David B Meya, Claudia M Denkinger, Conrad Muzoora, David R Boulware, ASTRO-CM Trial Team Tags: Articles Source Type: research

[Comment] Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?
Tuberculous meningitis, a severe manifestation of extra-pulmonary tuberculosis,1,2 has a mortality of more than 60% in HIV-infected people,3 with a 54% risk of chronic neurological complications in those who survive.2 Rapid diagnosis and early initiation of treatment are needed to improve prognosis and minimise debilitating sequelae.2 However, diagnosis is difficult, because cerebrospinal fluid typically contains few Mycobacterium tuberculosis bacilli and large sample volumes cannot always be obtained. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - September 14, 2017 Category: Infectious Diseases Authors: Margaret Khonga, Mark Patrick Nicol Tags: Comment Source Type: research

[Corrections] Corrections
This study was supported by Wellcome Trust awards 057434/Z/99/B (MAT, KZ, RM, TRV, JSF, RHG, and CAE), Z070005/Z/02/Z (MAT, TRV, JSF, RHG, and CAE), 078340/Z/05/Z (MAT, KZ, RM, TRV, JSF, and RHG, CAE) , 105788/Z/14/Z (SD, RHG, and CAE), 201251/Z/16/Z (MJS, RHG, and CAE), the Department for International Development Civil Society Challenge Fund (MAT, KZ, RM, TRV, CAE), the Joint Global Health Trials consortium (Medical Research Council, Department for International Development, and Wellcome Trust award MR/K007467/1 [TW, MAT, KZ, RM, TRV, RHG, and CAE]), the Bill& Melinda Gates Foundation (award OPP1118545 [TW, MAT, RM, TRV,...
Source: The Lancet Infectious Diseases - September 13, 2017 Category: Infectious Diseases Tags: Corrections Source Type: research