Long term management of people with post-tuberculosis lung disease
Korean J Intern Med. 2024 Jan;39(1):7-24. doi: 10.3904/kjim.2023.395. Epub 2024 Jan 1.ABSTRACTPost-tuberculosis lung disease (PTLD) is emerging as a significant area of global interest. As the number of patients surviving tuberculosis (TB) increases, the subsequent long-term repercussions have drawn increased attention due to their profound clinical and socioeconomic impacts. A primary obstacle to its comprehensive study has been its marked heterogeneity. The disease presents a spectrum of clinical manifestations which encompass tracheobronchial stenosis, bronchiectasis, granulomas with fibrosis, cavitation with associated...
Source: The Korean Journal of Internal Medicine - January 16, 2024 Category: Internal Medicine Authors: Wan Seo Hyung Woo Kim Ju Sang Kim Jinsoo Min Source Type: research

Biomarkers of the relationship of particulate matter exposure with the progression of chronic respiratory diseases
Korean J Intern Med. 2024 Jan;39(1):25-33. doi: 10.3904/kjim.2023.393. Epub 2024 Jan 1.ABSTRACTA high level of particulate matter (PM) in air is correlated with the onset and development of chronic respiratory diseases. We conducted a systematic literature review, searching the MEDLINE, EMBASE, and Cochrane databases for studies of biomarkers of the effect of PM exposure on chronic respiratory diseases and the progression thereof. Thirty-eight articles on biomarkers of the progression of chronic respiratory diseases after exposure to PM were identified, four of which were eligible for review. Serum, sputum, urine, and exha...
Source: The Korean Journal of Internal Medicine - January 16, 2024 Category: Internal Medicine Authors: Junghyun Kim Soo Jie Chung Woo Jin Kim Source Type: research

Diagnostic and therapeutic advances in adults with acute lymphoblastic leukemia in the era of gene analysis and targeted immunotherapy
Korean J Intern Med. 2024 Jan;39(1):34-56. doi: 10.3904/kjim.2023.407. Epub 2024 Jan 1.ABSTRACTAcute lymphoblastic leukemia (ALL) is one of the most rapidly changing hematological malignancies with advanced understanding of the genetic landscape, detection methods of minimal residual disease (MRD), and the development of immunotherapeutic agents with good clinical outcomes. The annual incidence of adult ALL in Korea is 300-350 patients per year. The WHO classification of ALL was revised in 2022 to reflect the molecular cytogenetic features and suggest new adverse- risk subgroups, such as Ph-like ALL and ETP-ALL. We continu...
Source: The Korean Journal of Internal Medicine - January 16, 2024 Category: Internal Medicine Authors: Jae-Ho Yoon Seok Lee Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSION: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | PMC:PMC10790052 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease severity
CONCLUSIONS: In this systematic review and meta-analysis of RCTs, it was found that remdesivir treatment did not show a substantial decrease in the risk of mortality. However, it was linked to a reduction in the necessity for additional ventilatory support, suggesting remdesivir could be beneficial for COVID-19 patients, particularly those who are not on MV.PMID:38151918 | DOI:10.3904/kjim.2023.357 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 28, 2023 Category: Internal Medicine Authors: Seungeun Ryoo Miyoung Choi Su-Yeon Yu Young Kyung Yoon Kyungmin Huh Eun-Jeong Joo Source Type: research

Efficacy and safety of denosumab treatment for Korean patients with Stage 3b-4 chronic kidney disease and osteoporosis
CONCLUSIONS: If carefully monitored and supplemented with calcium and vitamin D, denosumab treatment for 1 year provides significant benefits in patients with Stage 3b-4 CKD and osteoporosis. However, denosumab treatment did not affect coronary artery calcifications in these patients.PMID:38145616 | DOI:10.3904/kjim.2023.292 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 25, 2023 Category: Internal Medicine Authors: Jin Taek Kim You Mi Kim Kyong Yeun Jung Hoonsung Choi So Young Lee Hyo-Jeong Kim Source Type: research

Efficacy and safety of denosumab treatment for Korean patients with Stage 3b-4 chronic kidney disease and osteoporosis
CONCLUSIONS: If carefully monitored and supplemented with calcium and vitamin D, denosumab treatment for 1 year provides significant benefits in patients with Stage 3b-4 CKD and osteoporosis. However, denosumab treatment did not affect coronary artery calcifications in these patients.PMID:38145616 | DOI:10.3904/kjim.2023.292 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - December 25, 2023 Category: Internal Medicine Authors: Jin Taek Kim You Mi Kim Kyong Yeun Jung Hoonsung Choi So Young Lee Hyo-Jeong Kim Source Type: research