A 52-Week Study of Dose-Adjusted Subcutaneous Testosterone Enanthate in Oil Self-Administered via Disposable Auto-injector
This open-label, single-arm, dose-blinded, 52-week, registration-phase study evaluated the efficacy and safety of subcutaneous testosterone enanthate auto-injector (SCTE-AI) administered weekly to men with hypogonadism. (Source: The Journal of Urology)
Source: The Journal of Urology - October 5, 2018 Category: Urology & Nephrology Authors: Jed C. Kaminetsky, Andrew McCullough, Kathleen Hwang, Jonathan S. Jaffe, Christina Wang, Ronald S. Swerdloff Source Type: research
Can We Predict Functional Outcomes after Partial Nephrectomy?
Percent parenchymal mass-preserved (PPMP) is the primary determinant of functional outcomes after partial nephrectomy (PN). Accurate methods for predicting PPMP based on preoperative imaging could facilitate patient counseling. (Source: The Journal of Urology)
Source: The Journal of Urology - October 3, 2018 Category: Urology & Nephrology Authors: Hajime Tanaka, Yanbo Wang, Chalairat Suk-Ouichai, Diego Aguilar Palacios, Elvis R. Caraballo, Yunlin Ye, Erick M. Remer, Jianbo Li, Robert Abouassaly, Steven C. Campbell Source Type: research
Comparative Genomic Profiling of Refractory/Metastatic Penile and non-Penile Cutaneous Squamous Cell Carcinoma: Implications for Selection of Systemic Therapy
Metastatic penile squamous cell carcinoma (mPSCC) is an aggressive malignancy with limited treatment options. We compared the potential therapy impacting genomic alterations (GA) between mPSCC and non-penile cutaneous metastatic squamous cell carcinoma (mCSCC). (Source: The Journal of Urology)
Source: The Journal of Urology - October 3, 2018 Category: Urology & Nephrology Authors: J.M. Jacob, E.K. Ferry, L.M. Gay, J.A. Elvin, J. Vergilio, S. Ramkissoon, E. Severson, A. Necchi, J.K. Killian, S.M. Ali, A.B. Schrock, Nick W. Liu, J. Chung, V.A. Miller, P.J. Stephens, A. Welsh, R.J. Corona, J.S. Ross, G. Bratslavsky Source Type: research
Role of Residual Fragments on the Risk of Repeat Surgery After Flexible Ureteroscopy and Laser Lithotripsy: Single Center Study
To analyze the impact of residual stone fragments seen on abdominal X-ray (KUB) after ureteroscopy and laser lithotripsy (URS) on the risk of repeat surgical intervention. (Source: The Journal of Urology)
Source: The Journal of Urology - September 28, 2018 Category: Urology & Nephrology Authors: V. Iremashvili, S. Li, K.L. Penniston, S.L. Best, S.P. Hedican, S.Y. Nakada Source Type: research
3T Multiparametric MRI: Comparison of Performance With and Without Endorectal Coil for Prostate Cancer Detection, PI-RADSv2 Category and Staging with Whole Mount Histopathology Correlation in 429 Patients
To investigate performance of 3TmpMRI with and without endorectal coil (ERC) for detection of prostate cancer (PCa) with whole mount histopathology (WMHP) reference. (Source: The Journal of Urology)
Source: The Journal of Urology - September 28, 2018 Category: Urology & Nephrology Authors: Sohrab Afshari Mirak, Sepideh Shakeri, Amirhossein Mohammadian Bajgiran, Ely R. Felker, Kyung Hyun Sung, Nazanin Hajarol Asvadi, Pooria Khoshnoodi, Daniela Markovic, Danielle Ponzini, Preeti Ahuja, Anthony Sisk, Robert E. Reiter, David Lu, Steven S. Raman Source Type: research
Post-Operative Opiate Use in Urologic Patients: a Quality Improvement Study Aimed at Improving Opiate Disposal Practices
We aimed to determine trends in post-operative opiate management among urologic patients, to identify associations with opiate keeping, and to foster appropriate opiate disposal after surgery via introduction of an educational handout. (Source: The Journal of Urology)
Source: The Journal of Urology - September 26, 2018 Category: Urology & Nephrology Authors: Jackson Cabo, Ryan S. Hsi, Kristen R. Scarpato Source Type: research
Radical prostatectomy after vascular-targeted photodynamic therapy (VTP) with TOOKAD ® : feasibility, early and intermediate results
The objectives are to assess the feasibility of radical prostatectomy (RP) after VTP and describe functional and oncological outcomes. (Source: The Journal of Urology)
Source: The Journal of Urology - September 21, 2018 Category: Urology & Nephrology Authors: V. Pierrard, S. Lebdai, F. Kleinclauss, A.-R. Azzouzi, J.E. Terrier, E. Fortier, S. Joniau, H. Van Der Poel, G. Salomon, J. Casanova, R.-A. Medina-Lopez, E. Potiron, J. Rigaud, S. Vincendeau, J. Rassweiler, A. Villers, R. Gaston, C. Saussine, J. Giai, B. Source Type: research
Non-neuropathic Neuropathic Bladder: Is it Really Non-neuropathic?
Hinman Syndrome is a rare disease with urodynamic findings and clinical course that resemble neuropathic bladder and no neuropathic etiology. Diffusion Tensor Imaging (DTI) is a special magnetic resonance imaging (MRI) technique that has recently been used for peripheral nerves but shown to be applicable for evaluation of lumbosacral plexus. Our aim was to evaluate the lumbosacral plexus using DTI, which was not previously performed in Hinman Syndrome. (Source: The Journal of Urology)
Source: The Journal of Urology - September 21, 2018 Category: Urology & Nephrology Authors: Sibel Tiryaki, Cenk Eraslan, Tutku Soyer, Cem Calli, Ibrahim Ulman, Ali Avanoglu Source Type: research
Re: Correlations between Sonographic and Urodynamic Findings after Mid Urethral Sling Surgery
We congratulate the authors for accurately obtaining and presenting these data in clear, easy to understand images. Unfortunately their conclusion, ie the data support the notion that the mid urethral sling mechanism of action is dynamic urethral compression, is incorrect. (Source: The Journal of Urology)
Source: The Journal of Urology - September 20, 2018 Category: Urology & Nephrology Authors: Darren M. Gold, David Ende Tags: Letter to the Editor Source Type: research
Reply by Authors
It is unfortunate that Gold and Ende have misinterpreted the findings of our study in an attempt to support the integral theory. We believe the integral theory has no scientific validity and consider it a fallacy. (Source: The Journal of Urology)
Source: The Journal of Urology - September 20, 2018 Category: Urology & Nephrology Tags: Letter to the Editor Source Type: research
Editorial Comment
The authors attempted to develop and validate a decision support model to predict treatment success after a single session of lithotripsy in patients with ureteral stones. They included 15 factors in decision making. While the stone characteristics included in the model, such as stone bulk, density and depth from the skin, have been significant in impacting fragmentation following lithotripsy, renal function, too, is a logical inclusion. However, the impact of patient characteristics like age, gender or body mass index on fragmentation following lithotripsy have been variable. (Source: The Journal of Urology)
Source: The Journal of Urology - September 20, 2018 Category: Urology & Nephrology Authors: Rajesh K. Ahlawat Tags: New Technology and Techniques Source Type: research
Editorial Comment
It is exciting to see studies such as this one in which elegant technology was applied to improve medical decision making by using presumably more accurate means of prediction. In this case the example is machine learning to predict stone-free status after single session shock wave lithotripsy to treat ureteral stones. If the idea of seeing what machine learning can do for decision making does not excite you, just watch AlphaGo (DeepMind, London, United Kingdom) on Netflix ®! (Source: The Journal of Urology)
Source: The Journal of Urology - September 20, 2018 Category: Urology & Nephrology Authors: Michael W. Kattan Tags: New Technology and Techniques Source Type: research
Editorial Comment
Urinary stone disease is a growing and important public health problem in the United States. Tundo et al report the results of a cross-sectional analysis of data from the 2007 to 2012 NHANES, the gold standard for nationally representative health estimates. Focusing on younger adults, the authors compared the prevalence of self-reported stone disease by gender, finding an equal prevalence of stones (approximately 1/16) among men and women. These findings persisted after controlling for important potential confounders. (Source: The Journal of Urology)
Source: The Journal of Urology - September 19, 2018 Category: Urology & Nephrology Authors: Charles D. Scales Tags: Adult Urology Source Type: research
Editorial Comment
Recurrent lower urinary tract infections in women are a frustrating problem for patient and provider. Patients suffer with these infectious episodes, often at inconvenient times, and have very bothersome symptoms. Repeat courses of antibiotics put them at risk for yeast vaginitis and gastrointestinal disturbances including C. difficile colitis. These women also suffer from constant worry about when their next infection is going to strike. (Source: The Journal of Urology)
Source: The Journal of Urology - September 19, 2018 Category: Urology & Nephrology Authors: Anne Pelletier-Cameron Tags: Review Article Source Type: research
Editorial Comment
This rapid review with practice recommendations on the treatment and prevention of recurrent lower urinary tract infections in women is timely as the number of women affected by this condition, especially the older group, is rapidly growing in all of our practices. The authors should be congratulated for their large and detailed search of the best available literature on this topic and for offering a succinct algorithm of the favored alternatives for rUTI prevention and treatment. Notably, a quick glance at reference 3 pointing out the lack of consensus in the definition of rUTIs, and at the quality rating (AMSTAR 2) colum...
Source: The Journal of Urology - September 19, 2018 Category: Urology & Nephrology Authors: Philippe E. Zimmern Tags: Review Article Source Type: research
