A Prediction Model using Machine Learning Algorithm for Assessing Stone-Free Status after Single-Session Shockwave Lithotripsy to Treat Ureteral Stones
The aim of this study was to develop and validate a decision support model using machine learning algorithm to predict treatment success after single-session SWL in ureteral stone patients. (Source: The Journal of Urology)
Source: The Journal of Urology - July 20, 2018 Category: Urology & Nephrology Authors: Min Soo Choo, Saangyong Uhmn, Jong Keun Kim, Jun Hyun Han, Dong-Hoi Kim, Jin Kim, Seong Ho Lee Source Type: research
Editorial Comment
This post hoc analysis of the well-known dietary trial of Borghi et al (reference 15 in article) addresses a knowledge gap regarding whether urinary supersaturation indexes predict kidney stone recurrence. It is important to note that in the original study the 24-hour urine parameters dramatically improved after intervention at week 1 and the improvements were generally sustained in the following years. (Source: The Journal of Urology)
Source: The Journal of Urology - July 19, 2018 Category: Urology & Nephrology Authors: Ryan S. Hsi Tags: Adult Urology Source Type: research
Editorial Comment
Systemic chemotherapy prior to radical cystectomy has been shown to improve survival in MIBC with the best outcomes in patients who achieve a complete pathological response (pT0) (reference 8 in article). The current data from Audenet et al suggest that chemotherapy alone in select patients without cystectomy may result in up to 36% 5-year survival. The implication is that cystectomy can be safely delayed or even eliminated in some individuals with MIBC. However, these results must be interpreted with caution. (Source: The Journal of Urology)
Source: The Journal of Urology - July 18, 2018 Category: Urology & Nephrology Authors: Marc Dall ’Era, Primo N. Lara Tags: Adult Urology Source Type: research
Editorial Comment
In the current NCDB derived study short-term and long-term outcomes after chemotherapy of MIBC were evaluated in patients who did not undergo cystectomy or radiation after bladder tumor TUR. During a 10-year period 1,538 patients underwent chemotherapy alone after TUR while 17,866 underwent undergone cystectomy with or without chemotherapy. The authors noted that patients who did not undergo cystectomy had lower 30 and 90-day mortality rates than those who underwent cystectomy. The noncystectomy group was older, less insured, more likely to be African American, less likely to receive care at an academic facility and most i...
Source: The Journal of Urology - July 18, 2018 Category: Urology & Nephrology Authors: Michael Stern, John L. Phillips Tags: Adult Urology Source Type: research
Editorial Comment
Muscle invasive bladder cancer is a challenging disease to treat. Balancing long-term disease control while minimizing short-term and long-term morbidity and maximizing quality of life is difficult when your tools are relatively toxic systemic chemotherapy, radiation therapy and radical cystectomy. Historically the urological community has been slow to consider alternate treatments compared to radical cystectomy as reflected in the relatively low use of neoadjuvant chemotherapy and trimodal therapy. (Source: The Journal of Urology)
Source: The Journal of Urology - July 18, 2018 Category: Urology & Nephrology Authors: John D. Seigne Tags: Adult Urology Source Type: research
