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Featured articles for cme credit november 2022
No abstract available (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: CONTINUING MEDICAL EDUCATION PROGRAM Source Type: research

Trauma transfers discharged from the emergency department: Is there a role for telemedicine?
No abstract available (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: AUTHOR'S REPLY Source Type: research

Prehosptial low titer group O whole blood is feasible and safe: Results of a prospective randomized pilot trial
No abstract available (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: AUTHOR'S REPLY Source Type: research

Prehospital low titer group O whole blood: Difficult to conclude?
No abstract available (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: LETTER TO THE EDITOR Source Type: research

Response to letter to the editor, re: A multicenter validation of the modified brain injury guidelines: Are they safe and effective?
No abstract available (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: AUTHOR'S REPLY Source Type: research

Letter to editor re: A multicenter validation of the modified brain injury guidelines: Are they safe and effective?
No abstract available (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: LETTER TO THE EDITOR Source Type: research

Treatment of penetrating cardiac wounds for the general surgeon on call
“Scoop and run” approaches for severely injured patients have been adopted by emergency medical services over the past 40 years. This has resulted in more patients with severe injuries including penetrating cardiac wounds arriving at trauma centers and other acute care hospitals. General surgery trauma teams and general surgeons taking trauma call are the first responders for diagnosis, resuscitation, and operative management of injured patients. By natural selection, 96% to 98% of patients with signs of life on arrival to the trauma center after sustaining a penetrating cardiac wound have injuries that are amenable to...
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSION Source Type: research

Common bile duct stones management: A network meta-analysis
CONCLUSION This network meta-analysis suggests that both laparoscopic CBD exploration and intraoperative ERCP have equally good outcomes and provide a preferable single-anesthesia patient pathway with a shorter overall length of hospital stay compared with the two-stage approaches. LEVEL OF EVIDENCE Systematic Review/Meta Analysis; Level III. (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSION Source Type: research

Transcriptome reveals the dysfunction of pancreatic islets after wound healing in severely burned mice
CONCLUSION In the model of severe-burned mice, disorders in glucose metabolism persist for 8 weeks after burns, which may be related to low islet cell proliferation, downregulation of protein processing, and less ATP production. (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSIONS Source Type: research

Early expression of IL-10, IL-12, ARG1, and NOS2 genes in peripheral blood mononuclear cells synergistically correlate with patient outcome after burn injury
BACKGROUND No methods exist to rapidly and accurately quantify the immune insult created by burn injuries. The development of a rapid, noninvasive clinical biomarker assay that evaluates a burn patient's underlying immune dysfunction and predicts clinical outcomes could transform burn care. We aimed to determine a set of peripheral biomarkers that correlates with clinical outcomes of burn patients. METHODS This prospective observational study enrolled two patient cohorts within a single burn center into an institutionally approved institutional review board study. Blood draws were performed (Source: The Journal ...
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSIONS Source Type: research

In-hospital outcomes of intercostal nerve cryoablation and surgical stabilization of rib fractures
CONCLUSION Combining INCA with SSRF may further improve in-hospital outcomes for patients with traumatic rib fractures. LEVEL OF EVIDENCE Therapeutic/Care Management; Level III. (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSIONS Source Type: research

The extent to which geography explains one of trauma’s troubling trends: Insurance-based differences in appropriate interfacility transfer
The objective of this study was to explore geography's influence on variations in insurance transfer patterns, asking whether differences in distance and travel time by road from NTCs to the nearest level 1 or 2 trauma center alter the effect. As a secondary objective, differences in neighborhood socioeconomic disadvantage were also assessed. METHODS Adults (16–64 years) with major injuries (Injury Severity Score,>15) presenting to NTC emergency departments (EDs) were abstracted from 2007 to 2014 state inpatient/ED claims. Differences in the risk-adjusted odds of admission versus transfer were compared using mixed...
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSIONS Source Type: research

Does patient preference for online or telephone follow-up impact on response rates and data completeness following injury?
CONCLUSION More than half of trauma patients opted for online completion. Completion rates did differ depending on the questionnaire and telephone follow-up rates were higher. Nevertheless, given the wide diversity of the trauma population, the high rate of online uptake, and potential resource constraints, the study findings largely support the use of dual methods for follow-up. LEVEL OF EVIDENCE Prognostic/Epidemiological, Level III. (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: INDEPENDENT SUBMISSIONS Source Type: research

Sirtuin 1 deletion increases inflammation and mortality in sepsis
CONCLUSION Sirtuin 1 deletion increases systemic inflammation in sepsis. Renal mitochondrial dysfunction, kidney injury, and mortality following CLP were all exacerbated by SIRT1 deletion. Similar effects on inflammation and survival were seen following myeloid cell–specific SIRT1 deletion, indicating that SIRT1 activity in myeloid cells may be a significant contributor for the protective effects of SIRT1 in sepsis. (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Source: The Journal of Trauma: Injury, Infection, and Critical Care - November 1, 2022 Category: Orthopaedics Tags: EAST QUICK SHOT 2022 Source Type: research