Catechol-O-Methyltransferase Moderates the Association Between Dispositional Gratitude and Pain Outcomes
The val158met polymorphism of the COMT gene has been linked to pain as well as variation in cognitive-affective traits associated with pain, including gratitude. Although COMT and gratitude are associated with pain, less is known about whether these variables interact to influence pain. Thus, this study examined whether COMT genotype altered the relationship between gratitude and pain outcomes. Ninety-seven physical therapy patients (67% female, ages 18-90 years) completed validated self-report measures of gratitude and pain and provided buccal cell samples following a regularly scheduled therapy appointment. (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Georgiana Graef, Sebastian O ’Farrell, Sabra Tompkins, Luke Whartman, Alyssa Cudney, Taryn Cook, Nathan T. Deichert Source Type: research
Dynamics of Cognitive and Affective Adaptation to Chronic Low Back Pain: A Daily Diary Study
Constructs such as pain intensity, pain catastrophizing, pain-related injustice appraisal, and mood are comprised of stable and time-varying variance. Recent research indicates that pain-related injustice appraisals also show variability at the daily level; however, daily interrelationships between injustice appraisals and other pain-related constructs have not been examined in prior research. The current study is a secondary data analysis of an Internet-based 10-day daily diary dataset from 200 adults with chronic low back pain. (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: John A. Sturgeon, Anne Arewasikporn, Zina Trost Source Type: research
Effects of Acetaminophen in Psychosocial Context
The popular painkiller acetaminophen has psychological side-effects independent of relieving physical pain. I tested three hypotheses suggesting that acetaminophen ’s effects extend into the social realm: (1) Acetaminophen has unforeseen social side-effects, (2) psychosocial variables moderate the effects of acetaminophen on social behavior, and (3) social processes account for the effects of acetaminophen on social affect. In all studies, participants consu med 1000 mg acetaminophen or placebo. To test Hypothesis 1, participants completed measures of empathy (see Mischkowski, Crocker,& Way, 2016; 2019), and a measure of...
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Dominik Mischkowski Source Type: research
Emotional Support, Post-Traumatic Stress Disorder and Risk for Long-Term, High-Dose, Daily Prescription Opioid Use
Post-traumatic stress disorder (PTSD) is common in patients with chronic pain, adversely affects chronic pain outcomes, and is associated with opioid use and adverse opioid outcomes. Social support is a robust predictor of PTSD incidence and course as well as chronic pain outcome. We determined whether the association between PTSD and persistent opioid use was modified by emotional support in a cohort of patients receiving opioids for non-cancer pain. Eligible participants were ≥ 18, and had completed a new period of prescription opioid use lasting 30-90 days Bivariate association between cohort characteristics and each ...
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Mark Sullivan, Lauren Wilson, Matthew Amick, Lisa Miller-Matero, Timothy Chrusciel, Joanne Salas, Celeste Zabel, Patrick Lustman, Brian Ahmedani, Ryan Carpenter, Jeffrey Scherrer Source Type: research
Fear, Mobility, and Vitality: Outcomes from a Residential Functional Restoration Program for Veterans with Chronic Pain
It has been well-established that fear-avoidance pain behaviors have negative impacts on physical activity and quality of life in those with chronic pain. In the present study, we hypothesized pain-related fear, mobility, and vitality would significantly improve compared to baseline, after completing a 5-week residential functional restoration program (FRP) for Veterans with chronic pain. 144 Veterans with chronic pain [Mage=53.5 years (SD=10.87), 16.2% female, and 74.6% Caucasian] participated in a residential FRP within the VA Puget Sound Health Care System. (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Dustin S. Goerlitz, Jennifer L. DelVentura, Kelly Chinh, Laura M. Tuck, Erik W. Clarke Source Type: research
