Inconceivable: Outcomes of Contraception in LVAD-Supported Women of Childbearing Age
Purpose: Complete abstinence from pregnancy is recommended for women supported on durable left ventricular assist devices (LVAD). However, the safety and efficacy of hormonal contraception strategies in women on LVADs are not well described. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Weaver, S. Inglis, A. daSilva-deAbreu, P. Tang, A. Rosenbaum Source Type: research

Social Work Evaluation Domains Related to Caregiver Support and Mental Health are Strong Predictors of Risk of Readmission or Driveline Infection After HeartMate 3 (HM3)
Purpose: Social work (SW) assessment is a critical part of the evaluation for LVAD candidacy. Here we assessed the role of each component of a novel SW assessment tool structured across 6 domains (6D-SW) in predicting readmission or driveline infection (DLI) after LVAD. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M.R. Carey, S. Deluty, C. Shahidi, G.M. Mondellini, M. Tiburcio, B. Murphy, G. Sayer, Y. Kaku, N. Uriel, K. Takeda, M. Pavol, M. Yuzefpolskaya, P.C. Colombo Source Type: research

Glucagon-Like Peptide-1 Agonist Use for Obesity Treatment in Patients with Left Ventricular Assist Devices
Purpose: A BMI>35 kg/m2 is a relative contraindication for heart transplantation (HT) at many centers. Glucagon-like peptide-1 agonists (GLP-1a) are an effective weight loss treatment for patients with obesity. Whether GLP-1induces weight loss in obese patients with left ventricular assist devices (LVAD) and increases medical candidacy for HT is unknown. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M. Thomas, D. Varghese, L. Truby, C. Wrobel, E. Hardin, J. Thibodeau, M. Drazner, M. Peltz, M. Farr, J. Grodin, N. Hendren Source Type: research

Withdrawn
NA (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Source Type: research

Long-Term Outcomes of Substance Abusers Who Received a Durable Left Ventricular Assist Device (LVAD)
Purpose: The aim of this study was to assess the outcomes of LVAD recipients who were substance abusers at the time of implantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J. Nohl, S. Lehn, M. Urban Source Type: research

Pre- and Post-Transplant Diabetes Mellitus and the Risk of Infection and Mortality After Heart Transplantation
Purpose: Severe infections represent a detrimental complication for patients after heart transplantation (HTx). Diabetes Mellitus (DM) is a known risk factor for infectious diseases, but data on the impact of pre- or post-transplant DM on severe infections and death after HTx are scarce. We aimed to estimate the impact of pre- and post-transplant DM on the rate of hospitalizations for infections and all-cause mortality in HTx patients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , E. Mostofsky, S. Gupta, M. Kelm, A. Polzin, M.A. Mittleman Source Type: research

Multicenter Clinical Trial to Evaluate the Efficacy of a Preventive Strategy Against Cytomegalovirus Infection in Heart Transplant Patients Based on the Specific T Cells Response
This study aims to demonstrate that a preventive strategy against CMV infection in seropositive heart transplant adult patients, based on the specific T cell response, measured by IFN- γ ELISPOT assay, is effective and safe, compared to universal prophylaxis. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Diez-Lopez, O. Bestard, V. Donoso Trenado, M. Garc ía-Cosío, C. Ortiz-Bautista, F. Hernández-Pérez, D. Couto-Mallon, F. Gonzalez-Vilchez, L. De la fuente Galán, L. López-López, A. Grande Trillo, M. Gómez Molina, L. Rosenfeld Vilalta, S. Ibáà Source Type: research

Tolerability and Clinical Efficacy of Letermovir for Primary Cytomegalovirus Prophylaxis After Heart Transplantation
Purpose: Letermovir (LET) is a new antiviral that has successfully been used for primary Cytomegalovirus (CMV) prophylaxis (PPX) in kidney and stem cell transplant recipients. In our previously published cohort of 274 heart transplant (HT) recipients receiving 3 (CMV R+) or 6 (CMV D+/R-) months of valganciclovir PPX (or famciclovir PPX if CMV -/-), 30% developed neutropenia (absolute neutrophil count (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Vest, D. DeNofrio, D. Snydman Source Type: research

Varicella Zoster Virus Infections Following Pediatric Heart Transplantation: A Review of the Pediatric Health Information System (PHIS) Database
Purpose: The purpose of this study was to determine if post-transplant Varicella zoster virus (VZV) infections incur higher risk of morbidity and mortality after pediatric heart transplant. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S. Jani, L.D. Glass, C.M. Mery, C.D. Fraser, C.D. Castleberry Source Type: research

Fungal Infections After Heart Transplantation: A Single Center Observational Study
We describe the rates of IFI and death in the first year after HT at an academic medical center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Martino, M.I. Short, A.M. Strand, A. Vest, M.S. Kiernan, D. Snydman, J. Chow Source Type: research

Clinical Outcomes Among Impella 5.0/5.5 Recipients with Cardiogenic Shock: A Report from The Cardiogenic Shock Working Group
Purpose: The Impella 5.0 and 5.5 are large-bore trans-valvular mechanical circulatory support devices (MCSD) used in patients with cardiogenic shock (CS). Real world data evaluating clinical outcomes in patients supported with Impella 5.0/5.5 remain limited by small numbers or single center series. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J. Fried, J. Hernandez Montfort, S. Sinha, M. Kanwar, A. Garan, N. Uriel, B. LI, Q. Kong, P. Sangal, D. Burkoff, N. Kapur Source Type: research

The Impact of the Heart Allocation Policy Change on Pre-LVAD Temporary Mechanical Circulatory Support Utilization and on Outcomes
Purpose: The United Network for Organ Sharing (UNOS) updated the heart allocation policy (HAP) in October 2018. As a result, the use of temporary mechanical circulatory support (tMCS) devices as bridge to transplant (BTT) increased while durable left ventricular assist device (LVAD) implantation as BTT declined. The aim of this study was to compare clinical outcomes of tMCS devices as a bridge to LVAD before and after the HAP change. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Alexy, K. Mudy, S. Airhart, A. Shaffer, J. Kay, D. Emerson, A. Castleberry, M. Hyden, A. Christophy, B. Sun Source Type: research

Acute Limb Ischemia is an Important Target of Therapy to Decrease In-Hospital Mortality and is Associated with Endovascular Acute Mechanical Circulatory Support in Cardiogenic Shock
Purpose: Acute limb ischemia (ALI) is a devastating complication of cardiogenic shock (CS) Real world data evaluating outcomes of ALI in CS remain limited. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S. Vallabhajosyula, A. Kochar, S. Sinha, B. Li, C. Kong, P. Natov, M. Kanwar, J. Hernandez Montfort, A. Garan, K. John, P. Sangal, K. Walec, P. Zazzali, D. Burkhoff Source Type: research

Clinical Outcomes with Intra-Aortic Balloon Pump in Cardiogenic Shock Due to Acute Myocardial Infarction or Heart Failure: A Report from the Cardiogenic Shock Working Group
Purpose: Intra-aortic balloon pumps (IABPs) are the most used mechanical circulatory support devices (MCSD) in patients with cardiogenic shock (CS) in US. Real world data evaluating clinical outcomes in patients supported with IABP remain limited by small numbers. Moreover, there is lack of correlation of outcomes for the use of IABP in CS due to acute myocardial infarction (MI-CS) vs heart failure (HF-CS). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , N. Kapur, A. Garan, M. Kanwar, S. Sinha, J. Hernandez Montfort, B. Li, P. Sangal, K. Walec, P. Zazzali, Q. Kong, D. Burkoff Source Type: research

ECMO as a Bridge to Thoracic Multi-Organ Transplantation
This study aims to investigate temporal trends, utilization, and outcomes in ECMO as a bridge to thoracic multi-organ transplantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Krishnan, S. Elde, A. Garrison, M. Fawad, C. Ruaengsri, Y. Shudo, B.A. Guenthart, J. Woo, J.W. MacArthur Source Type: research