The Journal of Heart and Lung Transplantation This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Benchmarking Supervised Machine Learning Models for the Classification of Primary Graft Dysfunction
Purpose: Primary Graft Dysfunction (PGD) contributes to early post-lung transplantation (LTx) morbidity and mortality. Although chest X-ray and PaO2/FiO2 ratio are evaluated in PGD grading, multiple features interact and impact the development of PGD, and how these should be used in making clinical decisions remain doubtful. Thus, we aim to develop machine learning (ML) pipelines to predict patient classes based on our temporal PGD classification and compare their performance. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Khan, J. Van Slambrouck, C. Vandervelde, C. Vanluyten, X. Jin, A. Barbarossa, J. Kaes, L. Schoonjans, R. Vos, D. Van Raemdonck, P. Carmeliet, L. Ceulemans Source Type: research

Impact of COVID-19 Infection on the Development of Chronic Lung Allograft Dysfunction (CLAD) After Lung Transplantation
This study aims to evaluate the impact of COVID-19 infection on time-to-CLAD and survival in a large single-center study. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Benazzo, M. Aversa, Q. Li, S. Wang, E. Huszti, R. Ghany, J.T. Solera, D. Kumar, S. Keshavjee, T. Martinu, S. Juvet Source Type: research

Pulmonary Function Tests at 12 Months Post-Transplant Defines Long-Term Trajectories
Purpose: Purpose: There is a need for clinical markers predictive of long-term lung function post-transplant. We hypothesized that a data-driven assessment of lung function trajectories after transplant can predict long-term lung function. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S. Moshin, M. Carns, A. Arunachalam, C. Myers, R. Tomic, A. Misharin, M. Venkata Subramani Source Type: research

Lung Transplantation Outcomes in the United States Before and During the COVID-19 Pandemic
Purpose: The COVID-19 pandemic introduced numerous challenges to the field of thoracic transplantation. To investigate the impact of the COVID-19 pandemic on lung transplantation (LTx) outcomes, we compared survival between the pre-COVID and COVID eras in the United States. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Brown, , R. Yanagida, Y. Toyoda Source Type: research

Non-HLA Antibodies Are Associated with Chronic Lung Allograft Dysfunction in Lung Transplant Recipients
This study aimed to elucidate the role of non-HLA Abs on the development of chronic lung allograft dysfunction (CLAD) and overall survival in LTRs. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: K. Vyskocilov á, M. Röder, K. Vychytilová, A. Glosová, A. Zajacova, , A. Dutkova, L. Fila, R. Lischke, A. Slavčev, J. Havlin Source Type: research

Corticosteroid Dose Impacts Early Outcomes in Lung Allograft Recipients: A Dual-Center Study
Purpose: Early post-transplant corticosteroid (CS) dosing varies between programs, yet the impact on outcomes is unknown. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T.C. Lewis, L. Angel, S. Chang, D.B. Erasmus, M. Bacchetta, A.J. Trindade Source Type: research

Efficacy and Safety if JAK2 Inhibitor Plus Extracorporeal Photopheresis in Chronic Lung Allograft Dysfunction: A Single Centre Experience
Purpose: Post lung transplantation survival is limited by the development of chronic lung allograft dysfunction(CLAD),for which only few effective therapies exists and no standardized management. There are studies showing proven benefits of JAK2 inhibitor plus ECP in post bone marrow transplantation GVHD patients.We analysed JAK2 inhibitor plus ECP therapy in clinically diagnosed CLAD. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , V. Rahulan, M. Lalani, O. Tisekar, S. Priyaranjan, P. Dutta, A. Mohandas, M. B N, M. M, M. Sameer, S. Attawar Source Type: research

The 4-Year Outcome of the ScanCLAD Study
Purpose: The ScanCLAD trial showed a significant lower incidence of chronic lung allograft dysfunction (CLAD) three years after lung transplantation (LTx) in recipients treated with tacrolimus compared to cyclosporine. We now determine CLAD and survival outcomes at four years follow-up. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Kromann Lund, P. Raivio, I. Leuckfeld, J. Svahn, E.C. Holmberg, J. Magnusson Source Type: research

Impact of Right Heart Failure During the First Year of LVAD Support on Subsequent Survival and Late RHF Events Beyond 1 Year: An STS Intermacs Analysis
Purpose: The impact of right heart failure (RHF) during the first year of support with a magnetically levitated centrifugal flow LVAD (ML-LVAD) on outcomes beyond 1 year is not well characterized. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: I. Rajapreyar, J. Teuteberg, J. Kirklin, F. Pagani, P. Atluri, E. Grandin, J. Jacobs, B. Singletary, R. Cantor, G. Oliveira, J. Rame, Source Type: research

Cystatin C-Based Estimated Glomerular Filtration Rate is Independently Associated with Long-Term Mortality in HeartMate3 Patients
Purpose: An accurate assessment of kidney function is of paramount importance in the risk stratification of patients undergoing HeartMate 3 (HM3) implant. In this population, the high prevalence of sarcopenia and malnutrition may bias accuracy of serum creatinine (sCr)-based estimated glomerular filtration rate (eGFRsCr). Cystatin C (cysC)-based eGFR (eGFRcysC), an alternative assessment of kidney function, is less influenced by muscle mass and nutritional status. Herein, we investigated the association of pre-implant eGFRsCr and eGFRcysC with long-term mortality in a cohort of patients implanted with HM3. (Source: The Jou...
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Pinsino, M.A. Hynds, A. Vinogradsky, A. Ladanyi, G. Sayer, Y. Kaku, N. Uriel, K. Takeda, S.A. Husain, S. Mohan, P.C. Colombo, M. Yuzefpolskaya Source Type: research

Evaluation of Pulmonary Vasodilator Efficacy in LVAD Patients Using Invasive Right Heart Catheter Stress Testing
Purpose: Right heart failure following left ventricular assist device (LVAD) implantation is a major complication which significantly impairs exercise capacity (EC) and quality of life (QoL). Although pulmonary vasodilators, such as phosphodiesterase-5 inhibitors and soluble guanylate cyclase stimulators are commonly used for the treatment of pulmonary hypertension and right ventricular (RV) dysfunction in LVAD patients, the benefits of this practice remain unclear. The aim of this study was to evaluate the effect of pulmonary vasodilators on RV reserve, EC and QoL in LVAD patients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Sato, T. Nagai, K. Omote, K. Kamiya, T. Konishi, Y. Kobayashi, A. Tada, Y. Mizuguchi, Y. Takahashi, S. Naito, K. Saiin, S. Kazui, Y. Yasui, T. Hamaya, Y. Mori, S. Ishizaka, S. Wakasa, T. Anzai Source Type: research

Intermacs Analysis of Impact of Significant Post-LVAD Mitral Regurgitation on Outcomes
Purpose: Impact of significant post-implant mitral regurgitation (PI-MR) on left ventricular assist device (LVAD) outcomes remains controversial. We investigated the effect of PI-MR from a real-world experience. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Pienta, J. Pegues, T. Cascino, J. Cowger, A. Rosenbaum, R.B. Hawkins, M. Colvin, K. Aaronson, J. Yang, D. Likosky, F. Pagani, Source Type: research

Pulsatility of Pulmonary Artery Waveforms Before and After Left Ventricular Assist Device is Associated with Right Ventricular Failure
Purpose: Data have demonstrated potential utility of pulmonary artery pressure sensors for management of hemodynamics before and after left ventricular assist device (LVAD) implantation. The utility of a novel index of pulsatility for assessment of right ventricular failure is unknown. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Behfar, T. Rossman, S. Lundgren Source Type: research

Sublingual Microcirculation in Acute Mechanical Circulatory Support in Cardiogenic Shock
The objective of our study was to characterize the impact of different AMCS devices on the microcirculation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Lee, J. Baranowska, C. Moeller, A. Fernandez Valledor, G. Rubinstein, D. Oren, T. Miller, D. Lotan, A. Rahman, Y. Kaku, J. Raikhelkar, K. Takeda, E. DeFilippis, M. Yuzefpolskaya, P. Colombo, D. Majure, K. Clerkin, D. Burkhoff, G. Sayer, N. Uriel, J. Source Type: research

The Serum Sarcopenia Index is Associated with Post LVAD Mortality
Purpose: Low thoracic muscle mass and tissue quantified on preoperative chest CTs are associated with increased post LVAD mortality. The serum sarcopenia index (SI), a ratio between serum creatinine and cystatin C, correlates with CT quantified muscle measurements in several disease states. The purpose of this analysis was to determine whether the SI itself is associated with post LVAD mortality. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: J. Schultz, A. Keefe, V. Maharaj, T. Alexy, B. Ramu, T. Thenappan, M. Pritzker, F. Kamdar, D. Garry, A. Shaffer, R. John, Source Type: research