Assessing Negative Attributions After Brain Injury With the Ambiguous Intentions Hostility Questionnaire
Conclusion: Negative attributions were associated with anger and aggression responses, demonstrating construct validity of the AIHQ in the TBI population. Participants with TBI judged others' behaviors more severely than HCs, similar to prior research using a different attribution measure. The AIHQ has promise as a practical instrument for assessing negative attributions after TBI. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Traumatic Brain Injury-Related Emergency Department Visits Among American Indian and Alaska Native Persons—National Patient Information Reporting System, 2005-2014
Conclusion: Thousands of AI/AN children and adults are seen each year in emergency departments for TBI and the numbers increased over the 10-year period examined. Evidence-based interventions to prevent TBI-related emergency department visits, such as programs to reduce the risk for older adult falls and assault, are warranted. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Severity of Traumatic Brain Injury in Older Adults and Risk of Ischemic Stroke and Depression
Conclusion: In this group of older adults with TBI, higher TBI severity was associated with increased risk of ischemic stroke, but not depression. These results suggest that increased monitoring of older adults with moderate-severe TBI for stroke may be warranted. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Receipt of Treatment for Depression Following Traumatic Brain Injury
Conclusions: This study raises concerns about the management of depression following TBI. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Feasibility of Mild Traumatic Brain Injury Assessment Based on Cardiovascular Response to Postural Change
Conclusion: Noninvasive measurement of cardiovascular response to postural change is a promising approach for field-deployable post-mTBI screening. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Daily Morning Blue Light Therapy Improves Daytime Sleepiness, Sleep Quality, and Quality of Life Following a Mild Traumatic Brain Injury
Conclusion: Daytime sleepiness, fatigue, and sleep disruption are common following a mild traumatic brain injury. These findings further substantiate blue light therapy as a promising nonpharmacological approach to improve these sleep-related complaints with the added benefit of improved postconcussion symptoms and depression severity. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Behavior Problems Following Childhood TBI: The Role of Sex, Age, and Time Since Injury
Conclusions: Pediatric TBI is associated with high rates of behavior problems, with lower socioeconomic status predicting substantially elevated risk. Associations of higher levels of internalizing symptoms with greater time since injury highlight the importance of tracking children over time. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Letter to the Editor
No abstract available (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Special Feature Source Type: research

The Association of Saliva Cytokines and Pediatric Sports-Related Concussion Outcomes
This study aimed to explore cytokine alterations following pediatric sports-related concussion (SRC) and whether a specific cytokine profile could predict symptom burden and time to return to sports (RTS). Setting: Sports Medicine Clinic. Participants: Youth ice hockey participants (aged 12-17 years) were recruited prior to the 2013-2016 hockey season. Design: Prospective exploratory cohort study. Main Measure: Following SRC, saliva samples were collected and a Sport Concussion Assessment Tool version 3 (SCAT3) was administered within 72 hours of injury and analyzed for cytokines. Additive regression of decisio...
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Associations Between Neurochemistry and Gait Performance Following Concussion in Collegiate Athletes
Objective: To evaluate the strength of associations between single-task and dual-task gait measures and posterior cingulate gyrus (PCG) neurochemicals in acutely concussed collegiate athletes. Setting: Participants were recruited from an NCAA Division 1 University. Participants: Nineteen collegiate athletes acutely ( (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Microbial Diversity and Community Structures Among Those With Moderate to Severe TBI: A United States-Veteran Microbiome Project Study
Conclusion: Results suggest that moderate/severe TBI-related changes to the gut microbiome do not persist for years postinjury. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Impact of Age on Plasma Inflammatory Biomarkers in the 6 Months Following Mild Traumatic Brain Injury
Conclusion: The neuroinflammatory signature that accompanies mild TBI in older adults differs from that of younger adults. The differences seen are notable for their roles in neutrophil attraction (IL-8), neuronal-microglial-immune cell interactions (fractalkine), and chronic inflammation (IL-6). (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Early Tranexamic Acid Administration After Traumatic Brain Injury Is Associated With Reduced Syndecan-1 and Angiopoietin-2 in Patients With Traumatic Intracranial Hemorrhage
Conclusions: TXA may inhibit early upregulation of syndecan-1 and angiopoietin-2 in patients with MS-TBI, suggesting attenuation of protease-mediated vascular glycocalyx breakdown. The findings of this exploratory analysis should be considered preliminary and require confirmation in future studies. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Acute Time-Course Changes in CCL11, CCL2, and IL-10 Levels After Controlled Subconcussive Head Impacts: A Pilot Randomized Clinical Trial
Conclusion: Findings from this study suggest that 10 soccer headers do not provoke an acute inflammatory response. However, the acute CCL11 response may be influenced by prior exposure to soccer headers, providing a precedent for future field studies that prospectively track head impact exposure and changes in CCL11. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Neuroinflammatory Biomarkers Associated With Mild Traumatic Brain Injury History in Special Operations Forces Combat Soldiers
Conclusion: The SOF combat soldiers with mTBI history had increased NSE. Longitudinal studies in this population are needed due to between-subject heterogeneity in biomarker concentrations. The NfL concentrations in our SOF combat soldiers—regardless of mTBI history or recency—were similar to values previously reported in civilian acute TBI patients. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Traumatic Brain Injury and Inflammation: The Role of Local and Peripheral Participants in Short- and Long-Term Outcomes
No abstract available (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - September 1, 2020 Category: Neurology Tags: Commentary Source Type: research

The Discrepancy Between Cognitive Complaints and Neuropsychological Test Findings in Persons With Traumatic Brain Injury
Conclusions: Reconciling and interpreting subjective-objective discrepancies regarding cognitive functions following TBI are important tasks for case conceptualization and treatment planning. Depression is an important patient characteristic to consider when discrepancy patterns indicate underestimation of cognitive abilities. This study highlights the importance of assessing mood, a modifiable patient characteristic, with self-report symptom inventories. Future studies are needed to connect these findings with TBI outcomes. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

The Longitudinal Effects of Comorbid Health Burden on Functional Outcomes for Adults With Moderate to Severe Traumatic Brain Injury
Conclusions: This study offers evidence that comorbidity burden negatively impacts longitudinal functional and life satisfaction outcomes after TBI. The findings suggest that better identification and treatment of comorbidities may benefit life satisfaction, functional outcome, reduce healthcare costs, and decrease reinjury. Specific guidelines are needed for the management of comorbidities in TBI populations. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Concussion Symptoms Among Athletes: Preinjury Factors Predict Postinjury Factors
Conclusion: Preinjury symptom factors predicted postinjury symptom factors and age-associated differences in symptom factors may provide clinical value in prognostic models for subsequent postinjury clinical outcomes. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Incidence of New Neuropsychiatric Disorder Diagnoses Following Traumatic Brain Injury
Conclusions: In this large national study, rates of NPD were much higher among individuals with TBI than those in a non-TBI cohort, even before the TBI took place. TBI was associated with an increased risk of anxiety and PTSD diagnoses. Results from this study also suggest that individuals who sustain TBI have increased contact with the healthcare system during the months prior to injury, providing a window for intervention, especially for individuals diagnosed with alcohol dependence disorder. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Influence of Prior and Intercurrent Brain Injury on 5-Year Outcome Trajectories After Moderate to Severe Traumatic Brain Injury
Conclusion: Multiple brain injuries, particularly those of moderate or greater severity, have a significantly greater impact on patients' level of functioning compared with a single injury, but not the rate or shape of recovery. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Brain Volume in Veterans: Relationship to Posttraumatic Stress Disorder and Mild Traumatic Brain Injury
Conclusion: History of deployment TBI is independently associated with lower volumes in hippocampus and medial orbitofrontal cortex. These results support TBI as a potential contributing factor to consider in reduced cortical volume in PTSD. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Physical and Functional Impairment Among Older Adults With a History of Traumatic Brain Injury
Conclusion: History of TBI is associated with substantial PI and FI among community-dwelling older adults. Further research is warranted to determine whether aggressive management of neurobehavioral symptoms in this population may mitigate long-term PI and FI in this population. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Sleep Disturbances Following Traumatic Brain Injury in Older Adults: A Comparison Study
Conclusions: Sleep disturbances are highly prevalent in older adults with TBI. Gender differences, depression severity, and pain level are correlated with the occurrence of post-TBI sleep disturbances. Both OSA and insomnia are regarded as major contributors to low QOL in older people with TBI. Interventions targeted at post-TBI sleep disturbances may improve QOL of older adults. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Concussive Symptoms Following Pediatric Mild Traumatic Brain Injury
Conclusions: Children with mTBI have worse outcomes than children with SIH at follow-up, with parents more likely to report 1 or more ongoing symptoms if their children had an mTBI. Postinjury assessment of parental stress and ongoing symptom monitoring in young children with mTBI will allow for timely provision of support for the family. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Neurosensory Screening and Symptom Provocation in Pediatric Mild Traumatic Brain Injury
Conclusions: The diagnostic sensitivity/specificity of neurosensory testing in acutely concussed youth may be limited at 1 week postinjury as a function of natural recovery occurring in most emergency department cohorts. Neurosensory screening may have greater utility for identifying patients who experience delayed recovery. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Dopamine-Related Genes Moderate the Association Between Family Environment and Executive Function Following Pediatric Traumatic Brain Injury: An Exploratory Study
Conclusions: The findings highlight the importance of considering polygenetic and environmental factors in future studies of recovery following TBI and other injuries in childhood. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

The Association Between Community Participation and Social Internet Use Among Adults With Traumatic Brain Injury
Conclusions: The positive association between social Internet use and real-world social participation suggests that people with traumatic brain injury do not use social media as an alternative to real-world socialization. Rather, it is likely that similar barriers and facilitators affect both online and real-world social participation following traumatic brain injury. Emotional function should be considered as a moderating factor in further studies. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

A Clinical Trial Investigating Telehealth and In-Person Social Communication Skills Training for People With Traumatic Brain Injury: Participant-Reported Communication Outcomes
Conclusions: Whether delivered via telehealth or in-person, social communication skills training led to perceived positive change in communication skills. It was unexpected that outcomes for the telehealth group were better than for the in-person group on some variables. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - July 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Increased Risk of Stroke Among Young Adults With Serious Traumatic Brain Injury
Conclusions: These findings add to a growing body of work demonstrating that the acute and postacute stages of TBI play an accelerative role in AIS risk, particularly among younger patients, cervical artery dissection, and serious TBI. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

The Experience of Caregivers Following a Moderate to Severe Traumatic Brain Injury Requiring ICU Admission
Conclusions: This study provides new information about the experience of informal caregivers during the 6 months after their friend or family member survived a moderate to severe TBI. Interventions to promote caregiving may be a substantial opportunity to improve patient-centered outcomes following TBI. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Effect of Preexisting and Co-Occurring Comorbid Conditions on Recovery in the 5 Years After Rehabilitation for Traumatic Brain Injury
Objective: To determine the relationship between comorbid health conditions and the trajectory of functional recovery 5 years following traumatic brain injury (TBI) rehabilitation. Setting: Two acute rehabilitation facilities. Participants: A total of 407 patients with primary diagnosis of TBI. Design: Prospective, observational. Main Measures: Functional Independence Measure Cognitive and Motor scores. Results: Female gender was negatively associated with the trajectory of motor recovery (P (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

The Relationship Between Fighting Style, Cognition, and Regional Brain Volume in Professional Combatants: A Preliminary Examination Using Brief Neurocognitive Measures
Conclusions: Differences in RHIs across fighting styles may be of clinical significance. Exploring changes over time within the MA, boxer, and MMA cohorts may provide insight into longer-term discrepancies in subcortical regional brain volumes and cognitive functioning across fighting styles. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Impact of Secondary ADHD on Long-Term Outcomes After Early Childhood Traumatic Brain Injury
Objective: To examine the impact of secondary attention-deficit/hyperactivity disorder (SADHD) on long-term global and executive functioning in adolescents after traumatic brain injury (TBI). Setting: Three tertiary cared children's hospitals and 1 general hospital. Participants: One hundred twenty children (TBI: n = 54; orthopedic injury: n = 66) without preinjury ADHD evaluated approximately 6.8 years postinjury. Design: Cross-sectional data analysis from a prospective, longitudinal study. Main Measures: Outcomes included functional impairment (Child and Adolescent Functional Assessment Scale) and executive...
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Is Robotic Gait Training Feasible in Adults With Disorders of Consciousness?
Conclusions: Findings suggest inpatient-based RAGT may be safe and feasible to consider when developing a therapy plan of care in adults with DoC. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Association of Traumatic Brain Injury With Vestibular Dysfunction and Dizziness in Post-9/11 Veterans
Conclusions: There was a consistent, significant association between TBI and vestibular dysfunction or nonspecific dizziness, after controlling for sociodemographic factors, injury mechanism, and comorbid conditions. Given that most deployed post-9/11 veterans report blast and/or nonblast injuries, the need for prompt identification and management of these conditions and symptoms is clear. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

From Early Childhood to Adolescence: Lessons About Traumatic Brain Injury From the Ohio Head Injury Outcomes Study
Conclusions: Recovery after TBI is complex, varies over time, and involves injury-related and premorbid influences, cognition, genetics, and caregiver and family functioning. A sizable number of children with TBI have persisting unmet clinical needs. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

An International Exploration of the Effect of Media Portrayals of Postconcussion Management on Concussion Identification in the General Public
Conclusion: Additional player's injury management information influenced participants' judgments of concussion occurrence. Results show that information provided via sports media broadcasts influenced viewers' perceptions of concussion and appropriate concussion management. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Traumatic Brain Injury and Opioid Overdose Among Post-9/11 Veterans With Long-Term Opioid Treatment of Chronic Pain
Conclusion: TBI status, especially in the context of comorbid conditions, should be considered in clinical decisions regarding long-term use of opioids in patients with chronic pain. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Association Between Traumatic Brain Injury and Dementia in Veterans: A Rapid Systematic Review
Conclusion: Dementia prevalence is likely similar in Veteran and civilian populations, and the risk of dementia is likely increased by TBI. To inform development of screening, prevention, and rehabilitation efforts, research is still needed addressing the mechanism of association and timing of dementia onset. Protocol: PROSPERO; CRD42018107926. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Effects of Computerized Cognitive Training and Tai Chi on Cognitive Performance in Older Adults With Traumatic Brain Injury
Conclusion: Both CCT and TC may improve global cognition and different specific cognitive domains in older traumatic brain injury patients; the TC's effect may last for at least an additional 6 months. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Evaluation of a Brief, Skill-Building, Supportive, and Educational Intervention for Couples After Brain Injury
Conclusions: Investigation provided evidence that a curriculum-based education, skill-building, and supportive intervention can benefit couples for up to 3 months after treatment. Additional research is needed to ascertain the long-term benefits of intervention and the efficacy of alternative delivery methods (eg, Internet, telephone, and group). (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Online Family Problem-Solving Therapy (F-PST) for Executive and Behavioral Dysfunction After Traumatic Brain Injury in Adolescents: A Randomized, Multicenter, Comparative Effectiveness Clinical Trial
Conclusions: This comparative effectiveness study supports the utility of both self- and therapist-guided online F-PST in improving executive function behaviors in adolescents following TBI. Further work regarding clinical implementation and how best to integrate telehealth with ongoing rehabilitation care is warranted. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

North American Brain Injury Society
No abstract available (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Abstracts Source Type: research

The Incremental Hospitalization Cost of Significant Transport-Related Traumatic Brain Injury
This study aims to determine the incremental cost of acute hospitalization for traumatic brain injury (TBI) compared with matched controls. A second purpose is to identify the factors contributing to this hospital costs. Methodology: Analyses were performed on administrative data for injured patients, hospitalized in Belgium between 2009 and 2011 following a road traffic accident. Cases were matched to a control with similar injuries but without TBI. The incremental hospitalization cost of TBI and the factors contributing to the hospital costs were determined using multivariable regression modeling with gamma distributi...
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Self-Reported Lifetime Concussion Among Adults: Comparison of 3 Different Survey Questions
Conclusion: The current study suggested that in this sample of adults, the percentage reporting a concussion did not significantly vary by whether a concussion definition was provided or by the content of the definition. However, research suggests that prompting about mechanism of injury, listing symptoms individually, and considering only athletic populations may affect estimates and these factors should be included in future question comparisons. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

N-Acetyl-Aspartate in the Dorsolateral Prefrontal Cortex Long After Concussion in Youth
Conclusion: The presence of lower levels of DLPFC NAA suggests potential association of concussion in youth, although further investigation is needed, given that the result is driven by those with a single (and not multiple) concussion. Exploration of applying MRS in other brain regions is also warranted. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Pragmatic Language Comprehension After Pediatric Traumatic Brain Injury: A Scoping Review
Conclusion: The research suggests that children and adolescents with TBI, as compared with healthy or orthopedically injured controls, display deficits in comprehension of pragmatic language. Children with severe TBI demonstrate more widespread deficits in pragmatic comprehension abilities, whereas children with mild TBI show relatively intact pragmatic comprehension. Limitations and gaps identified in the literature warrant further research in this area. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

A Pilot Randomized Controlled Trial of Cognitive-Behavioral Therapy for Insomnia in Adolescents With Persistent Postconcussion Symptoms
Conclusion: In this pilot RCT, 6 weeks of CBT-I produced significant improvement in sleep in adolescents with persistent postconcussion symptoms. A larger trial is warranted. (Source: The Journal of Head Trauma Rehabilitation)
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research

Association of Simple Step Test With Readiness for Exercise in Youth After Concussion
Objectives: We hypothesized that a submaximal step test would be associated with readiness to commence graded exercise in children and adolescents with concussion. Methods: Children and adolescents aged 8 to 18 years performed standard concussion clinical assessment for vestibular/ocular and balance impairment, and exercise examination utilizing the 3-minute Kasch Pulse Recovery test (KPR) and a symptom-limited graded exercise test (GXT). Outcome measures included activity readiness and symptom exacerbation. Results: Forty-five participants (mean age 13.2 ± 2.1 years, 76% male) had a confirmed concussion (73...
Source: The Journal of Head Trauma Rehabilitation - March 1, 2020 Category: Neurology Tags: Focus on Clinical Research and Practice Source Type: research