How Important Is Adherence to Inhaled Medications Before Starting a Biologic Therapy for Asthma?
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Jonathan Corren, Reynold A. Panettieri (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Asthma and Allergic Disorders in Uganda: A Population-Based Study Across Urban and Rural Settings
We present a cross-sectional analysis of enrollment data from a population-based cohort study of adults aged ≥35 years in urban and rural Uganda. Sociodemographic and both lifetime and 12-month respiratory symptoms data were collected and spirometry was conducted following standard guidelines.ResultsIn 1,308 adults (median age 43.8 years and 52.3% female), we found an age-adjusted prevalence of 6.8% for asthma (9.8% urban, 4.3% rural; P
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Increased Dose and Duration of Statin Use Is Associated with Decreased Asthma-Related Emergency Department Visits and Hospitalizations
ConclusionsOur study suggests that statin use is associated with the decreased risk of asthma-related ED visits and/or hospitalizations in patients with asthma. A dose-response effect of statin use is also observed in this study. Therefore, future randomized clinical trials would be warranted to further evaluate the association. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Spirometry and Impulse Oscillometry in Preschool Children: Acceptability and Relationship to Maternal Smoking in Pregnancy
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Meyer Kattan, Leonard B. Bacharier, George T. O'Connor, Robyn Cohen, Ronald L. Sorkness, Wayne Morgan, Peter J. Gergen, Katy F. Jaffee, Cynthia M. Visness, Robert A. Wood, Gordon R. Bloomberg, Susan Doyle, Ryan Burton, James E. GernBackgroundComparisons of the technical acceptability of spirometry and impulse oscillometry (IOS) and clinical correlations of the measurements have not been well studied in young children. There are no large studies focused on African American and Hispan...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

A Randomized, Double-Blind, Placebo-Controlled Trial of Escitalopram in Patients with Asthma and Major Depressive Disorder
ConclusionsThe findings suggest that patients with more severe asthma and depression symptomatology may have a positive response, in terms of both asthma and depressive symptom reduction, to antidepressant treatment. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Tiotropium Attenuates Refractory Cough and Capsaicin Cough Reflex Sensitivity in Patients with Asthma
ConclusionTiotropium may alleviate asthmatic cough refractory to ICS/LABA by modulating cough reflex sensitivity but not through bronchodilation. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Outcome of 490 Desensitizations to Chemotherapy Drugs with a Rapid One-Solution Protocol
ConclusionsThis 1-solution protocol for desensitization has demonstrated to be safe and useful in our study population, especially for mild-to-moderate reactions and nonplatinum drugs. If our results were reproducible in other centers and larger populations, they could contribute to simplifying protocols and making desensitization available for more patients. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

The Basophil Activation Test Can Be of Value for Diagnosing Immediate Allergic Reactions to Omeprazole
ConclusionBAT represents a complementary tool for inclusion in the allergological workup for patients allergic to omeprazole. When combined with ST, it can be of value to guide the clinician as to whether to perform a DPT. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Anxiety and Depression Effects During Drug Provocation Test
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Laura Michelina Losappio, Alessandra Cappai, Alessandra Arcolaci, Iuliana Badiu, Patrizia Bonadonna, Elisa Boni, Claudia Bussolino, Marco Caminati, Pietro Galati, Enrico Heffler, Rossella Intravaia, Marina Mauro, Ilaria Massaro, Antonino Romano, Gabriele Rumi, Anna Parolo, Stefano Pizzimenti, Michele Nichelatti, Elide Anna PastorelloBackgroundDrug provocation test (DPT) represents the gold standard for the diagnosis of drug allergy. A DPT can be performed in a single-blind placebo-c...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Incidence and Risk of Oxaliplatin-Induced Hypersensitivity in Patients with Asymptomatic Prior Exposure: A Prospective Observational Study
ConclusionsPrevious exposure to oxaliplatin is a risk factor for earlier HSR onset and more severe and frequent HSR episodes, even if prior therapy was well tolerated. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

The Cost of Self-Reported Penicillin Allergy: A Systematic Review
ConclusionsEvaluations of clinical and economic outcomes of PCN allergy are primarily observational and focus on inpatient populations. Long-term relationships between PCN allergy and clinical and economic outcomes are unknown. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Steroid Allergy: Clinical Features and the Importance of Excipient Testing in a Diagnostic Algorithm
ConclusionsPatients with respiratory manifestations were significantly more likely to be truly allergic. CS allergies are rare and may be overdiagnosed without excipient testing. We suggest the use of Carmellose eye drops as a readily available source of carboxymethylcellulose for testing and propose a comprehensive diagnostic algorithm for suspected CS allergy. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Cross-Reactivity and Tolerability of Cephalosporins in Patients with IgE-Mediated Hypersensitivity to Penicillins
ConclusionsCross-reactivity between penicillins and cephalosporins seems to be mainly related to side chain similarity or identity. Subjects with an IgE-mediated hypersensitivity to penicillins could be treated with cephalosporins such as cefuroxime and ceftriaxone that have side-chain determinants different from those of penicillins and are negative in pretreatment skin testing. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Efficacy and Safety of 5-Day Challenge for the Evaluation of Nonsevere Amoxicillin Allergy in Children
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Roxane Labrosse, Louis Paradis, Jonathan Lacombe-Barrios, Kathryn Samaan, François Graham, Jean Paradis, Philipps Bégin, Anne Des RochesBackgroundPenicillin allergy is the most frequent drug allergy, among which aminopenicillins are reputed for causing delayed rashes in children, particularly in the context of viral infections. Despite a negative allergy evaluation, a significant proportion of individuals continue to avoid penicillin antibiotics for fear of an allergic...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Comparison of Basophil Activation Test and Skin Testing Performances in NMBA Allergy
ConclusionIn our technical conditions, BAT does not replace skin testing in the assessment of NMBA allergy. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Hypersensitivity to Neuromuscular Blocking Agents: Can Skin Tests Give the Green Light for Re-Exposure?
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Vito Sabato, Didier G. Ebo (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Diagnostic Value of Tryptase in Food Allergic Reactions: A Prospective Study of 160 Adult Peanut Challenges
The objective of this study was to determine whether tryptase rises in food allergic reactions, optimal sampling time points, and a diagnostic cutoff for confirming a clinical reaction.MethodsCharacterized peanut allergic patients were recruited and underwent up to 4 peanut challenges and 1 placebo challenge each. Tryptase was measured serially on challenge days both before (baseline) and during the challenge. The peak percentage tryptase rise (peak/baseline) was related to reaction severity. Receiver operating characteristic (ROC) curves were generated establishing an optimal diagnostic cutoff.ResultsTryptase was analyzed...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Long-Term Follow-Up After Baked Milk Introduction
ConclusionsThe majority of patients who underwent a BM challenge, including those who failed their challenge, were able to progress to direct or less-cooked forms of milk. However, adverse reactions were common, and even a successful BM challenge does not guarantee future tolerance of BM or preclude later reactions, even to previously tolerated doses. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Prevalence and Outcomes of Primary Immunodeficiency in Hospitalized Children in the United States
ConclusionsThe prevalence of PIDDs in the hospitalized pediatric population in the United States may have increased over time. Younger age is associated with higher mortality, hospital costs, and LOS. Further study is needed to determine cost-effective management strategies to improve outcomes in infants and young children with PIDD. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Systemic Reactions in Pediatric Patients Receiving Standardized Allergen Subcutaneous Immunotherapy with and without Seasonal Dose Adjustment
ConclusionsStandardized SCIT appears to be associated with an SR rate of 0.429% to 0.364% of visits in pediatric patients. Protocol modification did not lead to a significant drop in SR. Larger multicenter studies are required to further evaluate the rate of SRs from standardized SCIT. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

The Burden of Rhinitis and the Impact of Medication Management within the Community Pharmacy Setting
ConclusionsThe majority of the participants with rhinitis selected suboptimal medications from community pharmacy highlighting the significant burden of rhinitis in community pharmacy and the contribution of medication management. Pharmacists need to take a proactive and evidence-based role in the management of rhinitis supported by clinical pathways when need to be articulated and promoted in all rhinitis guidelines. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Onset of Action of the Fixed Combination Intranasal Azelastine-Fluticasone Propionate in an Allergen Exposure Chamber
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Jean Bousquet, Eli O. Meltzer, Peter Couroux, Arkady Koltun, Ferdinand Kopietz, Ullrich Munzel, Hans Christian Kuhl, Duc Tung Nguyen, Anne Marie Salapatek, David PriceBackgroundA fixed-dose combination of intranasal azelastine hydrochloride and fluticasone propionate (MP-AzeFlu) is the most effective treatment of allergic rhinitis, but its onset of action requires further investigation.ObjectiveTo compare the onset of action of MP-AzeFlu with the free combination of oral loratadine ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema
ConclusionsIn patients with frequent HAE attacks, a treatment strategy of routine prevention with self-administered twice weekly C1-INH(SC) had a greater impact on improving multiple HAE-related HRQoL impairments, most notably anxiety and work productivity, compared with on-demand treatment alone (placebo prophylaxis). (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Fixed Drug Eruption Related to Cefixime in an Adolescent Case
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): İlknur Kulhas Celik, Betul Buyuktiryaki, Emine Dibek Misirlioglu, Ezgi Hasbek, Can Naci Kocabas (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Apixaban Causing Leukocytoclastic Vasculitis
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Usama Bin Nasir, Aswini Kumar, Arti Easwar (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Immune modulation in a patient with Morquio syndrome treated with enzyme replacement therapy
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Angela Sun, Walaa Alshuaibi, Daniel Petroni, Suzanne Skoda-Smith, Michael J. Goldberg, Susan Hale (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Smell loss is associated with severe and uncontrolled disease in children and adolescents with persistent allergic rhinitis
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Franklin Mariño-Sanchez, Meritxell Valls-Mateus, Oliver Haag, Isam Alobid, Jean Bousquet, Joaquim Mullol (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

A penicillin skin testing initiative in an outpatient allergy office
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Allison Ramsey, S. Shahzad Mustafa (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Treatment with the SQ house dust mite sublingual immunotherapy tablet may be initiated year-round
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Hendrik Nolte, David I. Bernstein, Jörg Kleine-Tebbe, Peter A. Fejerskov, Qing Li, Susan Lu, Harrold S. Nelson (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Successful subcutaneous desensitization in a patient with allergy to ixekizumab
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Ruth Barranco Jimenez, Daiana Guillen Vera, Raquel Rivera-Díaz, Susana Cortijo-Cascajares, Ruth Mielgo Ballesteros, María del Carmen Diéguez Pastor (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Liver disturbances in activated phosphoinositide 3-kinase δ syndrome
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Gil Ben-Yakov, Devika Kapuria, Jamie Marko, Min Ho Cho, Stefania Pittaluga, David Erwin Kleiner, Christopher Koh, Steven Holland, Gulbu Uzel, Theo Heller (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

DRESS Syndrome due to benzylpenicillin with cross-reactivity to amoxicillin
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Timothy J. Watts, Philip H. Li, Rubaiyat Haque (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Partial RAG deficiency in a patient with varicella infection, autoimmune cytopenia, and anticytokine antibodies
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Vera Goda, Aniko Malik, Tibor Kalmar, Zoltan Maroti, Bhumika Patel, Boglarka Ujhazi, Krisztian Csomos, Jaime E. Hale, Karin Chen, Jacob Bleesing, Paolo Palma, Caterina Cancrini, Anne M. Comeau, Gergely Krivan, Jolan E. Walter (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Ara h 2 basophil activation test does not predict clinical reactivity to peanut
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Alexandra Chapuis, Jonathan Thevenot, Frédéric Coutant, Khaled Messaoudi, Elodie Michaud, Bruno Pereira, Emmanuelle Rochette, Nelly Gourdon-Dubois, Etienne Merlin, Jean-Luc Fauquert, Bertrand Evrard, Paul Rouzaire (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Male X-chromosome mosaicism leading to carrier phenotype and inheritance of chronic granulomatous disease
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Stephanie Harris, Helen Braggins, Karin van Leeuwen, Kimberly Gilmour, Matthew S. Buckland, Dirk Roos, David M. Lowe (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Conjunctivitis occurring in atopic dermatitis patients treated with dupilumab–clinical characteristics and treatment
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Andreas Wollenberg, Lieneke Ariens, Stephan Thurau, Chantal van Luijk, Marlene Seegräber, Marjolein de Bruin-Weller (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Allergic myocardial infarction (Kounis syndrome) after cefuroxime with side-chain cross-reactivity
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Magdalena Absmaier, Tilo Biedermann, Knut Brockow (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Implementation of guidelines for early peanut introduction at a pediatric academic center
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): David R. Stukus, Ben T. Prince, Irene Mikhail (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Coca-Cola allergy identified as fructose-induced anaphylaxis
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Chang-Gyu Jung, Eun-Mi Yang, Ji-Ho Lee, Seung-Hyun Kim, Hae-Sim Park, Yoo Seob Shin (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

The B antigen protects against the development of red meat allergy
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Jonathan R. Brestoff, Merih T. Tesfazghi, Mark A. Zaydman, Ronald Jackups, Brian S. Kim, Mitchell G. Scott, Ann M. Gronowski, Brenda J. Grossman (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

A survey of caregiver perspectives on emergency epinephrine autoinjector sharing
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Marcus Shaker, Tsuzumi Kanaoka, Robert G.P. Murray, Dana Toy, Susan Shaker, Aurora Drew (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Disseminated abscesses due to Mycoplasma faucium in a patient with activated PI3Kδ syndrome type 2
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Nerea Dominguez-Pinilla, Luis M. Allende, Jérémie Rosain, Maria del Carmen Gallego, Fernando Chaves, Caroline Deswarte, Esther Viedma, Jaime de Inocencio Arocena, Jesús Ruiz-Contreras, Jacinta Bustamante, Luis Ignacio Gonzalez-Granado (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Eosinophilic Esophagitis
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): Benjamin L. Wright, Jonathan M. Spergel (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

CME Exam: Eosinophilic Esophagitis
Publication date: September–October 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 5Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

The use of medical alert jewelry to communicate allergy information
Publication date: Available online 5 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Thanh-Thao (Adriana) Le, Caroline Foreman, William Smith (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Recall urticaria - a new clinical sign in the diagnosis of alpha-gal syndrome
Publication date: Available online 5 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Paul Schmidle, Klara Reidenbach, Claudia Kugler, Bernadette Eberlein, Tilo Biedermann, Ulf Darsow (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

Fatal asthma: an audit of 30 million patient-years of health plan membership from 2007 to 2015
ConclusionsAudit-confirmed fatal asthma is more likely to occur in younger, non-smoking, individuals, using very low rates of preventive inhalers. This will be a very difficult group to prospectively identify and manage effectively. Further research into the reasons for early death after HEDIS asthma dataset inclusion is warranted. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2018 Category: Allergy & Immunology Source Type: research

Bronchial Thermoplasty: A Decade of Experience: State of The Art
Publication date: Available online 5 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Laren D. Tan, Ken Y. Yoneda, Samuel Louie, D.Kyle Hogarth, Mario CastroAbstract:Bronchial thermoplasty (BT) delivers targeted radiofrequency energy to bronchial airway walls and results in the partial ablation of the airway smooth muscle that is responsible for bronchoconstriction. It is approved for the treatment of severe persistent asthma. Multiple, large clinical trials including a recent “real-world” study demonstrate significant improvements in asthma-related quality of life, re...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2018 Category: Allergy & Immunology Source Type: research

Children with neutrophil-predominant severe asthma have pro-inflammatory neutrophils with enhanced survival and impaired clearance
ConclusionsChildren with neutrophil-predominant severe asthma have pro-inflammatory neutrophils with enhanced survival. Airway macrophages are also pro-inflammatory and dysfunctional and may contribute to global innate immune impairment. Therapies that target neutrophils and related inflammation may be warranted in this subset of children. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2018 Category: Allergy & Immunology Source Type: research

Patient versus allergy specialist interpretation of a negative workup for suspected iodinated contrast media allergy
Publication date: Available online 5 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rik Schrijvers, Christine Breynaert, Jean-Luc Bourrain, Pascal Demoly, Anca Mirela Chiriac (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2018 Category: Allergy & Immunology Source Type: research