The International Journal of Biochemistry and Cell Biology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains
Int J Biochem Cell Biol. 2023 Sep 29:106475. doi: 10.1016/j.biocel.2023.106475. Online ahead of print.ABSTRACTTau has canonically been considered as an axonal protein, but studies have observed tau localization in other subcellular domains of neurons. This relocated tau has been identified in both physiological and pathological conditions, and it is often labeled mislocalized. Furthermore, these forms of tau are referred to as "hyperphosphorylated" without specifying the phosphosites involved. On the contrary, we speculate that tau may have multiple physiological functions in various locations regulated via specific phosph...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Amanda Schneeweis Daniel T S Pak Source Type: research
ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1-driven ROS production
Int J Biochem Cell Biol. 2023 Sep 30;164:106474. doi: 10.1016/j.biocel.2023.106474. Online ahead of print.ABSTRACTResistance to radio and chemotherapy in Glioblastoma (GBM) is correlated with its malignancy, invasiveness, and aggressiveness. The Rho GTPase pathway plays important roles in these processes, but its involvement in the GBM response to genotoxic treatments remains unsolved. Inhibition of this signaling pathway has emerged as a promising approach for the treatment of CNS injuries and diseases, proving to be a strong candidate for therapeutic approaches. To this end, Rho-associated kinases (ROCK), classic downstr...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Yuli Thamires Magalhaes Fabio Luis Forti Source Type: research
Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains
Int J Biochem Cell Biol. 2023 Sep 29:106475. doi: 10.1016/j.biocel.2023.106475. Online ahead of print.ABSTRACTTau has canonically been considered as an axonal protein, but studies have observed tau localization in other subcellular domains of neurons. This relocated tau has been identified in both physiological and pathological conditions, and it is often labeled mislocalized. Furthermore, these forms of tau are referred to as "hyperphosphorylated" without specifying the phosphosites involved. On the contrary, we speculate that tau may have multiple physiological functions in various locations regulated via specific phosph...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Amanda Schneeweis Daniel T S Pak Source Type: research
ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1-driven ROS production
Int J Biochem Cell Biol. 2023 Sep 29:106474. doi: 10.1016/j.biocel.2023.106474. Online ahead of print.ABSTRACTResistance to radio and chemotherapy in Glioblastoma (GBM) is correlated with its malignancy, invasiveness, and aggressiveness. The Rho GTPase pathway plays important roles in these processes, but its involvement in the GBM response to genotoxic treatments remains unsolved. Inhibition of this signaling pathway has emerged as a promising approach for the treatment of CNS injuries and diseases, proving to be a strong candidate for therapeutic approaches. To this end, Rho-associated kinases (ROCK), classic downstream ...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Yuli Thamires Magalhaes Fabio Luis Forti Source Type: research
Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains
Int J Biochem Cell Biol. 2023 Sep 29:106475. doi: 10.1016/j.biocel.2023.106475. Online ahead of print.ABSTRACTTau has canonically been considered as an axonal protein, but studies have observed tau localization in other subcellular domains of neurons. This relocated tau has been identified in both physiological and pathological conditions, and it is often labeled mislocalized. Furthermore, these forms of tau are referred to as "hyperphosphorylated" without specifying the phosphosites involved. On the contrary, we speculate that tau may have multiple physiological functions in various locations regulated via specific phosph...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Amanda Schneeweis Daniel T S Pak Source Type: research
ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1-driven ROS production
Int J Biochem Cell Biol. 2023 Sep 29:106474. doi: 10.1016/j.biocel.2023.106474. Online ahead of print.ABSTRACTResistance to radio and chemotherapy in Glioblastoma (GBM) is correlated with its malignancy, invasiveness, and aggressiveness. The Rho GTPase pathway plays important roles in these processes, but its involvement in the GBM response to genotoxic treatments remains unsolved. Inhibition of this signaling pathway has emerged as a promising approach for the treatment of CNS injuries and diseases, proving to be a strong candidate for therapeutic approaches. To this end, Rho-associated kinases (ROCK), classic downstream ...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Yuli Thamires Magalhaes Fabio Luis Forti Source Type: research
Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains
Int J Biochem Cell Biol. 2023 Sep 29:106475. doi: 10.1016/j.biocel.2023.106475. Online ahead of print.ABSTRACTTau has canonically been considered as an axonal protein, but studies have observed tau localization in other subcellular domains of neurons. This relocated tau has been identified in both physiological and pathological conditions, and it is often labeled mislocalized. Furthermore, these forms of tau are referred to as "hyperphosphorylated" without specifying the phosphosites involved. On the contrary, we speculate that tau may have multiple physiological functions in various locations regulated via specific phosph...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Amanda Schneeweis Daniel T S Pak Source Type: research
ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1-driven ROS production
Int J Biochem Cell Biol. 2023 Sep 29:106474. doi: 10.1016/j.biocel.2023.106474. Online ahead of print.ABSTRACTResistance to radio and chemotherapy in Glioblastoma (GBM) is correlated with its malignancy, invasiveness, and aggressiveness. The Rho GTPase pathway plays important roles in these processes, but its involvement in the GBM response to genotoxic treatments remains unsolved. Inhibition of this signaling pathway has emerged as a promising approach for the treatment of CNS injuries and diseases, proving to be a strong candidate for therapeutic approaches. To this end, Rho-associated kinases (ROCK), classic downstream ...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Yuli Thamires Magalhaes Fabio Luis Forti Source Type: research
Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains
Int J Biochem Cell Biol. 2023 Sep 29:106475. doi: 10.1016/j.biocel.2023.106475. Online ahead of print.ABSTRACTTau has canonically been considered as an axonal protein, but studies have observed tau localization in other subcellular domains of neurons. This relocated tau has been identified in both physiological and pathological conditions, and it is often labeled mislocalized. Furthermore, these forms of tau are referred to as "hyperphosphorylated" without specifying the phosphosites involved. On the contrary, we speculate that tau may have multiple physiological functions in various locations regulated via specific phosph...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Amanda Schneeweis Daniel T S Pak Source Type: research
ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1-driven ROS production
Int J Biochem Cell Biol. 2023 Sep 29:106474. doi: 10.1016/j.biocel.2023.106474. Online ahead of print.ABSTRACTResistance to radio and chemotherapy in Glioblastoma (GBM) is correlated with its malignancy, invasiveness, and aggressiveness. The Rho GTPase pathway plays important roles in these processes, but its involvement in the GBM response to genotoxic treatments remains unsolved. Inhibition of this signaling pathway has emerged as a promising approach for the treatment of CNS injuries and diseases, proving to be a strong candidate for therapeutic approaches. To this end, Rho-associated kinases (ROCK), classic downstream ...
Source: The International Journal of Biochemistry and Cell Biology - October 1, 2023 Category: Biochemistry Authors: Yuli Thamires Magalhaes Fabio Luis Forti Source Type: research
Role of innate lymphoid cells in cancer metastasis
Int J Biochem Cell Biol. 2023 Oct;163:106465. doi: 10.1016/j.biocel.2023.106465. Epub 2023 Sep 4.ABSTRACTMetastatic spread of cancer accounts for most cancer-related deaths. Cancer seeding in secondary organs requires reprogramming of the local stromal and immune landscape, which ultimately supports tumour growth. Yet, the cellular and molecular mechanisms that promote this tumour-permissive environment remain largely unknown. Innate lymphoid cells (ILCs) have recently been shown to modulate the immune response to cancer in multiple ways. Given their tissue-resident nature, ILCs are well placed to respond to local cues wit...
Source: The International Journal of Biochemistry and Cell Biology - September 4, 2023 Category: Biochemistry Authors: Julia Moreno-Vicente Timotheus Yf Halim Source Type: research
Role of innate lymphoid cells in cancer metastasis
Int J Biochem Cell Biol. 2023 Oct;163:106465. doi: 10.1016/j.biocel.2023.106465. Epub 2023 Sep 4.ABSTRACTMetastatic spread of cancer accounts for most cancer-related deaths. Cancer seeding in secondary organs requires reprogramming of the local stromal and immune landscape, which ultimately supports tumour growth. Yet, the cellular and molecular mechanisms that promote this tumour-permissive environment remain largely unknown. Innate lymphoid cells (ILCs) have recently been shown to modulate the immune response to cancer in multiple ways. Given their tissue-resident nature, ILCs are well placed to respond to local cues wit...
Source: The International Journal of Biochemistry and Cell Biology - September 4, 2023 Category: Biochemistry Authors: Julia Moreno-Vicente Timotheus Yf Halim Source Type: research
Role of innate lymphoid cells in cancer metastasis
Int J Biochem Cell Biol. 2023 Oct;163:106465. doi: 10.1016/j.biocel.2023.106465. Epub 2023 Sep 4.ABSTRACTMetastatic spread of cancer accounts for most cancer-related deaths. Cancer seeding in secondary organs requires reprogramming of the local stromal and immune landscape, which ultimately supports tumour growth. Yet, the cellular and molecular mechanisms that promote this tumour-permissive environment remain largely unknown. Innate lymphoid cells (ILCs) have recently been shown to modulate the immune response to cancer in multiple ways. Given their tissue-resident nature, ILCs are well placed to respond to local cues wit...
Source: The International Journal of Biochemistry and Cell Biology - September 4, 2023 Category: Biochemistry Authors: Julia Moreno-Vicente Timotheus Yf Halim Source Type: research
Role of innate lymphoid cells in cancer metastasis
Int J Biochem Cell Biol. 2023 Oct;163:106465. doi: 10.1016/j.biocel.2023.106465. Epub 2023 Sep 4.ABSTRACTMetastatic spread of cancer accounts for most cancer-related deaths. Cancer seeding in secondary organs requires reprogramming of the local stromal and immune landscape, which ultimately supports tumour growth. Yet, the cellular and molecular mechanisms that promote this tumour-permissive environment remain largely unknown. Innate lymphoid cells (ILCs) have recently been shown to modulate the immune response to cancer in multiple ways. Given their tissue-resident nature, ILCs are well placed to respond to local cues wit...
Source: The International Journal of Biochemistry and Cell Biology - September 4, 2023 Category: Biochemistry Authors: Julia Moreno-Vicente Timotheus Yf Halim Source Type: research
Role of innate lymphoid cells in cancer metastasis
Int J Biochem Cell Biol. 2023 Oct;163:106465. doi: 10.1016/j.biocel.2023.106465. Epub 2023 Sep 4.ABSTRACTMetastatic spread of cancer accounts for most cancer-related deaths. Cancer seeding in secondary organs requires reprogramming of the local stromal and immune landscape, which ultimately supports tumour growth. Yet, the cellular and molecular mechanisms that promote this tumour-permissive environment remain largely unknown. Innate lymphoid cells (ILCs) have recently been shown to modulate the immune response to cancer in multiple ways. Given their tissue-resident nature, ILCs are well placed to respond to local cues wit...
Source: The International Journal of Biochemistry and Cell Biology - September 4, 2023 Category: Biochemistry Authors: Julia Moreno-Vicente Timotheus Yf Halim Source Type: research
