Recovery of suspended reimbursements of high-cost drugs subjected to monitoring registries and negotiated agreements (MEAs): a tool for governance and clinical appropriateness in the Italian reality
AbstractThe Monitoring Registries and negotiated agreements (MEAs) established by the Italian Medicines Agency (AIFA) exemplify a pinnacle of excellence in Italian healthcare governance, playing a pivotal role in achieving economic sustainability and ensuring judicious allocation of financial resources. Within a local territorial health company catering to a populace of around 1 million individuals in Italy, an assessment of the meticulous implementation of all negotiation procedures was carried out by scrutinizing the monitoring records. This examination served to pinpoint and address potential issues in the platform mana...
Source: The European Journal of Health Economics - January 20, 2024 Category: Health Management Source Type: research

Correction: Braving the waves: exploring capability well-being patterns in seven European countries during the COVID-19 pandemic
(Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - January 20, 2024 Category: Health Management Source Type: research

A state-level analysis of macro-level factors associated with hospital readmissions
AbstractInvestigation of the factors that contribute to hospital readmissions has focused largely on individual level factors. We extend the knowledge base by exploring macrolevel factors that may contribute to readmissions. We point to environmental, behavioral, and socioeconomic factors that are emerging as correlates to readmissions. Data were taken from publicly available reports provided by multiple agencies. Partial Least Squares –Structural Equation Modeling was used to test the association between economic stability and environmental factors on opioid use which was in turn tested for a direct association with hos...
Source: The European Journal of Health Economics - January 20, 2024 Category: Health Management Source Type: research

Looking inside the lab: a systematic literature review of economic experiments in health service provision
AbstractExperimental economics is, nowadays, a well-established approach to investigate agents ’ behavior under economic incentives. In the last decade, a fast-growing number of studies have focused on the application of experimental methodology to health policy issues. The results of that stream of literature have been intriguing and strongly policy oriented. However, those findings are sc attered between different health-related topics, making it difficult to grasp the overall state-of-the-art. Hence, to make the main contributions understandable at a glance, we conduct a systematic literature review of laboratory expe...
Source: The European Journal of Health Economics - January 11, 2024 Category: Health Management Source Type: research

Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people
ConclusionThe free at point of use online eczema self-management intervention was low cost to run and cost-effective.Trial registrationThis trial was registered prospectively with the ISRCTN registry (ISRCTN79282252). URLwww.EczemaCareOnline.org.uk. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - January 9, 2024 Category: Health Management Source Type: research

The impact of an ‘evergreening’ strategy nearing patent expiration on the uptake of biosimilars and public healthcare costs: a case study on the introduction of a second administration form of trastuzumab in The Netherlands
AbstractIn this paper, we explore dynamic market share and public healthcare costs of trastuzumab ’s evergreening (subcutaneous) variant during introduction of trastuzumab’s competitive biosimilar variants in the Netherlands. We used a time series design to assess dynamic market share of trastuzumab’s evergreening variant after introducing trastuzumab’s biosimilar variants, focusing on t he number of treatments and patients. The public healthcare costs of this evergreening strategy were estimated using administrative claims data. Our results show that the original trastuzumab was completely replaced by the subcutan...
Source: The European Journal of Health Economics - January 8, 2024 Category: Health Management Source Type: research

Lifecycle model-based evaluation of infant 4CMenB vaccination in the UK
ConclusionsHALM-based CBA provides an empirically richer, more utility –theoretically grounded approach to vaccine evaluation than CUA, demonstrating good value for money for legislatures (based on private values) and for all decision-makers (based on social values). (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - January 5, 2024 Category: Health Management Source Type: research

Risk adjustment for regional healthcare funding allocations with ensemble methods: an empirical study and interpretation
AbstractWe experiment with recent ensemble machine learning methods in estimating healthcare costs, utilizing Finnish data containing rich individual-level information on healthcare costs, socioeconomic status and diagnostic data from multiple registries. Our data are a random 10% sample (553,675 observations) from the Finnish population in 2017. Using annual healthcare cost in 2017 as a response variable, we compare the performance of Random forest, Gradient Boosting Machine (GBM) and eXtreme Gradient Boosting (XGBoost) to linear regression. As machine learning methods are often seen as unsuitable in risk adjustment appli...
Source: The European Journal of Health Economics - January 3, 2024 Category: Health Management Source Type: research

Impact of Long COVID on productivity and informal caregiving
ConclusionLC significantly impacts productivity losses and provision of informal care, exacerbated by high national prevalence of LC. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - December 26, 2023 Category: Health Management Source Type: research