Can redistribution of vaccine improve global welfare? Lessons from COVID-19
AbstractThe disparity in the distribution of COVID-19 vaccine has been recorded with more than 70% vaccination rate for high-income countries as compared to less than 40% for low-income countries. The low affordability of vaccines for the majority of low-income group invites the need for redistribution of vaccines. The disproportionate donation of vaccines across the globe motivates us to explore the incentive for the high-income group to redistribute. An exploratory analysis of cross-country COVID-19 vaccination distribution data shows that the countries which have received vaccines as donation has also contributed to vac...
Source: The European Journal of Health Economics - February 29, 2024 Category: Health Management Source Type: research

Preference-based utility weights for the Individualized Neuromuscular Quality of Life Questionnaire (INQoL), with a focus on non-dystrophic myotonia (NDM)
DiscussionThe hybrid modelling approach allows us to combine data from the two methodologies and maximize the information from each to inform the utility weights for the INQoL. The TTO is the more conventional valuation method, but combined with the larger DCE study produced better descriptive coverage. This is a relatively novel method for estimating weights which we think is particularly well suited to economic evaluations of orphan drugs. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - February 28, 2024 Category: Health Management Source Type: research

A principled approach to non-discrimination in cost-effectiveness
AbstractThe US Inflation Reduction Act (IRA) prohibits the Centers for Medicare and Medicaid Services (CMS) from using standard quality-adjusted life-years or other value assessment methods that discriminate against the aged, terminally ill, or disabled when setting maximum fair prices for prescription drugs. This policy has reignited interest in methods for assessing value without discrimination. Equal value of life-years gained (EVL), healthy years in total (HYT), and Generalized Risk-Adjusted Cost-Effectiveness (GRACE) have emerged as proposals. Neither EVL nor HYT rests on well-articulated microeconomic foundations. We...
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

Systematic methodological review of health state values in glaucoma cost-utility analyses
Conclusions and relevanceThis review describes that few CUAs describe important rationale for using health state utility values. Including additional details on the search, appraisal, selection, and inclusion process of health utility values improves transparency, generalizability and supports the assessment of the validity of study conclusions. Future investigations should aim to use health utilities on the same scale of measurement across health states and consider the source and relevance to the decision context/purpose of conducting that cost-utility study. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

The role of budget impact and its relationship with cost-effectiveness in reimbursement decisions on health technologies in the Netherlands
This article used policy reports and Ministerial correspondence to discuss and elucidate the role of budget impact and its relationship with cost-effectiveness in reimbursement decisions in the Netherlands. The results indicate that CEAs and BIAs are both considered important for informing these decisions. While the requirements regarding CEAs —and application of the associated decision rule—are consistent across the different stages, the same does not hold for BIAs. Importantly, the definition of and evidence on budget impact differs between stages. Some important aspects (e.g. substitution and saving effects) typical...
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

Assessment of health state utilities associated with adult and pediatric acid sphingomyelinase deficiency (ASMD)
DiscussionGreater severity of ASMD was associated with lower mean utility. Results have implications for valuation of pediatric health states. The resulting utilities may be useful in cost-utility modeling estimating the value of treatment for ASMD. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

A principled approach to non-discrimination in cost-effectiveness
AbstractThe US Inflation Reduction Act (IRA) prohibits the Centers for Medicare and Medicaid Services (CMS) from using standard quality-adjusted life-years or other value assessment methods that discriminate against the aged, terminally ill, or disabled when setting maximum fair prices for prescription drugs. This policy has reignited interest in methods for assessing value without discrimination. Equal value of life-years gained (EVL), healthy years in total (HYT), and Generalized Risk-Adjusted Cost-Effectiveness (GRACE) have emerged as proposals. Neither EVL nor HYT rests on well-articulated microeconomic foundations. We...
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

Systematic methodological review of health state values in glaucoma cost-utility analyses
Conclusions and relevanceThis review describes that few CUAs describe important rationale for using health state utility values. Including additional details on the search, appraisal, selection, and inclusion process of health utility values improves transparency, generalizability and supports the assessment of the validity of study conclusions. Future investigations should aim to use health utilities on the same scale of measurement across health states and consider the source and relevance to the decision context/purpose of conducting that cost-utility study. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

The role of budget impact and its relationship with cost-effectiveness in reimbursement decisions on health technologies in the Netherlands
This article used policy reports and Ministerial correspondence to discuss and elucidate the role of budget impact and its relationship with cost-effectiveness in reimbursement decisions in the Netherlands. The results indicate that CEAs and BIAs are both considered important for informing these decisions. While the requirements regarding CEAs —and application of the associated decision rule—are consistent across the different stages, the same does not hold for BIAs. Importantly, the definition of and evidence on budget impact differs between stages. Some important aspects (e.g. substitution and saving effects) typical...
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

Assessment of health state utilities associated with adult and pediatric acid sphingomyelinase deficiency (ASMD)
DiscussionGreater severity of ASMD was associated with lower mean utility. Results have implications for valuation of pediatric health states. The resulting utilities may be useful in cost-utility modeling estimating the value of treatment for ASMD. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - February 27, 2024 Category: Health Management Source Type: research

Measuring EQ-5D-5L utility values in parents who have experienced perinatal death
ConclusionsPerinatal death has important and long-lasting health impacts on parents. Mental health support following perinatal bereavement is especially important. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - February 25, 2024 Category: Health Management Source Type: research

Unravelling risk selection in Spanish general government employee mutual funds: evidence from cancer hospitalizations in the public health network
AbstractGovernment employees in Spain are covered by public Mutual Funds that purchase a uniform basket of benefits, equal to the ones served to the general population, from private companies. Companies apply as private bidders for a fixed per capita premium hardly adjusted by age. Our hypothesis is that this premium does not cover risks, and companies have incentives for risk selection, which are more visible in high-cost patients. We focus on a particularly costly disease, cancer, whose prevalence is similar among government employees and the general population. We compare hospitalisations in the public hospitals of the ...
Source: The European Journal of Health Economics - February 20, 2024 Category: Health Management Source Type: research