Trimethylamine N-oxide (TMAO), choline and its metabolites are associated with the risk of nonalcoholic fatty liver disease
Br J Nutr. 2024 Mar 6:1-24. doi: 10.1017/S0007114524000631. Online ahead of print.ABSTRACTIt is inconclusive whether trimethylamine N-oxide (TMAO) and choline and related metabolites, namely, trimethylamine (TMA), L-carnitine, betaine, and dimethylglycine (DMG), are associated with nonalcoholic fatty liver disease (NAFLD). Our objective was to investigate these potential associations. Additionally, we sought to determine the mediating role of TMAO. In this 1:1 age- and sex-matched case‒control study, a total of 150 pairs comprising NAFLD cases and healthy controls were identified. According to the fully adjusted model, a...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Rong Ma Guangying Shi Yanfang Li Han Shi Source Type: research

The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats
Br J Nutr. 2024 Mar 6:1-28. doi: 10.1017/S0007114524000382. Online ahead of print.ABSTRACTThe primary goal of the investigation was to analyze the anti-inflammatory, and antioxidant properties of Gamma-linolenic acid (GLA) on rats with Indomethacin (IND)-induced gastric ulcers. Thirty rats were divided into five groups: Control, IND (50 mg/kg, p.o.), IND pretreated with GLA 100 mg/kg (p.o. for 14 days), IND pretreated with GLA 150 mg/kg (p.o. for 14 days), and IND pretreated with omeprazole (20 mg/kg, p.o. for 14 days). The stomach tissues were examined to calculate the ulcer index, and pH, and analyze biochemical markers ...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Kaveh Rahimi Masoumeh Ezzati Givi Anahita Rezaie Mohammad Hekmatmanesh Ysamin Shaker Ardakani Source Type: research

Effects of beef fat enriched with trans vaccenic acid and < em > cis < /em > 9, < em > trans < /em > 11-conjugated linoleic acid on glucose homeostasis and hepatic lipid accumulation in high-fat diet induced obese mice
The objective of this study was to determine the effects of beef fat naturally enriched with TVA and RA on parameters related to glucose homeostasis and associated metabolic markers in diet-induced obese (DIO) mice. Thirty-six male C57BL/6J mice (8 weeks old) were fed for 19 weeks with either a control low-fat diet (CLF), a control high fat diet (CHF), or a TVA+RA-enriched high fat diet (EHF). Compared with CLF, feeding either CHF or EHF resulted in adverse metabolic outcomes associated with high fat diets, including adiposity, impaired glucose control, and hepatic steatosis. However, the EHF diet induced a significantly h...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Yanqing Xu Ming-Fo Hsu Fawaz Haj Payam Vahmani Source Type: research

Higher Dietary Methyl Donor Micronutrient Consumption is Associated with Higher Muscle Strength in Adults: A Cross-Sectional Study
In conclusion, our findings revealed that higher dietary methyl donor micronutrient consumption is associated with enhanced muscle strength. As a result, advice on a higher intake of methyl donor-rich foods including grains, nuts, dairy, and seafood might be recommended by dietitians as a general guideline to adhere to. Additional prospective studies are needed to confirm the findings.PMID:38443195 | DOI:10.1017/S0007114524000424 (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Amin Mirrafiei Parisa Radkhah Mahla Chambari Samira Davarzani Nadia Babaee Kurosh Djafarian Sakineh Shab-Bidar Source Type: research

Trimethylamine N-oxide (TMAO), choline and its metabolites are associated with the risk of nonalcoholic fatty liver disease
Br J Nutr. 2024 Mar 6:1-24. doi: 10.1017/S0007114524000631. Online ahead of print.ABSTRACTIt is inconclusive whether trimethylamine N-oxide (TMAO) and choline and related metabolites, namely, trimethylamine (TMA), L-carnitine, betaine, and dimethylglycine (DMG), are associated with nonalcoholic fatty liver disease (NAFLD). Our objective was to investigate these potential associations. Additionally, we sought to determine the mediating role of TMAO. In this 1:1 age- and sex-matched case‒control study, a total of 150 pairs comprising NAFLD cases and healthy controls were identified. According to the fully adjusted model, a...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Rong Ma Guangying Shi Yanfang Li Han Shi Source Type: research

The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats
Br J Nutr. 2024 Mar 6:1-28. doi: 10.1017/S0007114524000382. Online ahead of print.ABSTRACTThe primary goal of the investigation was to analyze the anti-inflammatory, and antioxidant properties of Gamma-linolenic acid (GLA) on rats with Indomethacin (IND)-induced gastric ulcers. Thirty rats were divided into five groups: Control, IND (50 mg/kg, p.o.), IND pretreated with GLA 100 mg/kg (p.o. for 14 days), IND pretreated with GLA 150 mg/kg (p.o. for 14 days), and IND pretreated with omeprazole (20 mg/kg, p.o. for 14 days). The stomach tissues were examined to calculate the ulcer index, and pH, and analyze biochemical markers ...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Kaveh Rahimi Masoumeh Ezzati Givi Anahita Rezaie Mohammad Hekmatmanesh Ysamin Shaker Ardakani Source Type: research

Effects of beef fat enriched with trans vaccenic acid and < em > cis < /em > 9, < em > trans < /em > 11-conjugated linoleic acid on glucose homeostasis and hepatic lipid accumulation in high-fat diet induced obese mice
The objective of this study was to determine the effects of beef fat naturally enriched with TVA and RA on parameters related to glucose homeostasis and associated metabolic markers in diet-induced obese (DIO) mice. Thirty-six male C57BL/6J mice (8 weeks old) were fed for 19 weeks with either a control low-fat diet (CLF), a control high fat diet (CHF), or a TVA+RA-enriched high fat diet (EHF). Compared with CLF, feeding either CHF or EHF resulted in adverse metabolic outcomes associated with high fat diets, including adiposity, impaired glucose control, and hepatic steatosis. However, the EHF diet induced a significantly h...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Yanqing Xu Ming-Fo Hsu Fawaz Haj Payam Vahmani Source Type: research

Higher Dietary Methyl Donor Micronutrient Consumption is Associated with Higher Muscle Strength in Adults: A Cross-Sectional Study
In conclusion, our findings revealed that higher dietary methyl donor micronutrient consumption is associated with enhanced muscle strength. As a result, advice on a higher intake of methyl donor-rich foods including grains, nuts, dairy, and seafood might be recommended by dietitians as a general guideline to adhere to. Additional prospective studies are needed to confirm the findings.PMID:38443195 | DOI:10.1017/S0007114524000424 (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Amin Mirrafiei Parisa Radkhah Mahla Chambari Samira Davarzani Nadia Babaee Kurosh Djafarian Sakineh Shab-Bidar Source Type: research

Trimethylamine N-oxide (TMAO), choline and its metabolites are associated with the risk of nonalcoholic fatty liver disease
Br J Nutr. 2024 Mar 6:1-24. doi: 10.1017/S0007114524000631. Online ahead of print.ABSTRACTIt is inconclusive whether trimethylamine N-oxide (TMAO) and choline and related metabolites, namely, trimethylamine (TMA), L-carnitine, betaine, and dimethylglycine (DMG), are associated with nonalcoholic fatty liver disease (NAFLD). Our objective was to investigate these potential associations. Additionally, we sought to determine the mediating role of TMAO. In this 1:1 age- and sex-matched case‒control study, a total of 150 pairs comprising NAFLD cases and healthy controls were identified. According to the fully adjusted model, a...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Rong Ma Guangying Shi Yanfang Li Han Shi Source Type: research

The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats
Br J Nutr. 2024 Mar 6:1-28. doi: 10.1017/S0007114524000382. Online ahead of print.ABSTRACTThe primary goal of the investigation was to analyze the anti-inflammatory, and antioxidant properties of Gamma-linolenic acid (GLA) on rats with Indomethacin (IND)-induced gastric ulcers. Thirty rats were divided into five groups: Control, IND (50 mg/kg, p.o.), IND pretreated with GLA 100 mg/kg (p.o. for 14 days), IND pretreated with GLA 150 mg/kg (p.o. for 14 days), and IND pretreated with omeprazole (20 mg/kg, p.o. for 14 days). The stomach tissues were examined to calculate the ulcer index, and pH, and analyze biochemical markers ...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Kaveh Rahimi Masoumeh Ezzati Givi Anahita Rezaie Mohammad Hekmatmanesh Ysamin Shaker Ardakani Source Type: research

Effects of beef fat enriched with trans vaccenic acid and < em > cis < /em > 9, < em > trans < /em > 11-conjugated linoleic acid on glucose homeostasis and hepatic lipid accumulation in high-fat diet induced obese mice
The objective of this study was to determine the effects of beef fat naturally enriched with TVA and RA on parameters related to glucose homeostasis and associated metabolic markers in diet-induced obese (DIO) mice. Thirty-six male C57BL/6J mice (8 weeks old) were fed for 19 weeks with either a control low-fat diet (CLF), a control high fat diet (CHF), or a TVA+RA-enriched high fat diet (EHF). Compared with CLF, feeding either CHF or EHF resulted in adverse metabolic outcomes associated with high fat diets, including adiposity, impaired glucose control, and hepatic steatosis. However, the EHF diet induced a significantly h...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Yanqing Xu Ming-Fo Hsu Fawaz Haj Payam Vahmani Source Type: research

Higher Dietary Methyl Donor Micronutrient Consumption is Associated with Higher Muscle Strength in Adults: A Cross-Sectional Study
In conclusion, our findings revealed that higher dietary methyl donor micronutrient consumption is associated with enhanced muscle strength. As a result, advice on a higher intake of methyl donor-rich foods including grains, nuts, dairy, and seafood might be recommended by dietitians as a general guideline to adhere to. Additional prospective studies are needed to confirm the findings.PMID:38443195 | DOI:10.1017/S0007114524000424 (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Amin Mirrafiei Parisa Radkhah Mahla Chambari Samira Davarzani Nadia Babaee Kurosh Djafarian Sakineh Shab-Bidar Source Type: research

Trimethylamine N-oxide (TMAO), choline and its metabolites are associated with the risk of nonalcoholic fatty liver disease
Br J Nutr. 2024 Mar 6:1-24. doi: 10.1017/S0007114524000631. Online ahead of print.ABSTRACTIt is inconclusive whether trimethylamine N-oxide (TMAO) and choline and related metabolites, namely, trimethylamine (TMA), L-carnitine, betaine, and dimethylglycine (DMG), are associated with nonalcoholic fatty liver disease (NAFLD). Our objective was to investigate these potential associations. Additionally, we sought to determine the mediating role of TMAO. In this 1:1 age- and sex-matched case‒control study, a total of 150 pairs comprising NAFLD cases and healthy controls were identified. According to the fully adjusted model, a...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Rong Ma Guangying Shi Yanfang Li Han Shi Source Type: research

The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats
Br J Nutr. 2024 Mar 6:1-28. doi: 10.1017/S0007114524000382. Online ahead of print.ABSTRACTThe primary goal of the investigation was to analyze the anti-inflammatory, and antioxidant properties of Gamma-linolenic acid (GLA) on rats with Indomethacin (IND)-induced gastric ulcers. Thirty rats were divided into five groups: Control, IND (50 mg/kg, p.o.), IND pretreated with GLA 100 mg/kg (p.o. for 14 days), IND pretreated with GLA 150 mg/kg (p.o. for 14 days), and IND pretreated with omeprazole (20 mg/kg, p.o. for 14 days). The stomach tissues were examined to calculate the ulcer index, and pH, and analyze biochemical markers ...
Source: The British Journal of Nutrition - March 5, 2024 Category: Nutrition Authors: Kaveh Rahimi Masoumeh Ezzati Givi Anahita Rezaie Mohammad Hekmatmanesh Ysamin Shaker Ardakani Source Type: research

Educational Intervention Based on the Extended Parallel Process Model Improves Adherence to Diabetic Diet and Glycemic Control Indices: a Randomized, Double-blind, Controlled, Factorial Field Trial
Br J Nutr. 2024 Mar 1:1-35. doi: 10.1017/S0007114524000497. Online ahead of print.ABSTRACTNutritional education is pivotal in the medical nutritional therapy of type 2 diabetes Mellitus (T2DM). The extended parallel process model (EPPM) is a health education method for inducing desirable health behaviors. The present study aimed to investigate the effect of nutritional education based on the EPPM in T2DM patients on knowledge, attitude, practice (KAP), anthropometric indices, glycemic factors, lipid profile, and adherence to the diabetic diet. A randomized, double-blind, controlled, factorial field trial was designed for T...
Source: The British Journal of Nutrition - March 1, 2024 Category: Nutrition Authors: Tayebe Dehghan Mohammad Ali Mohsenpour Masoud Karimi Manoosh Mehrabi Morteza Zare Marzieh Akbarzadeh Atefeh Kohansal Fatemeh Fathi Zahra Sohrabi Source Type: research