Does the presence of sentinel lymph node macrometastases in breast cancer patients require axillary lymph node dissection? —Single‐center analysis
Abstract
According to the current guidelines on treatment of breast cancer patients, identification of metastases in the sentinel lymph node (SLN (+)) is not an absolute indication for necessary axillary lymph node dissection (ALND). In our study, we present long‐term outcomes of treatment among SLN(+) patients referred for conservative treatment, for example, no further ALND. A total of 3145 breast cancer patients subjected to sentinel lymph node biopsy (SLNB) between November 2008 and June 2015. SLN metastases were identified in 719 patients (22.9%). Locoregional recurrences and distant metastases as endpoints were dis...
Source: The Breast Journal - February 24, 2018 Category: Cancer & Oncology Authors: Tomasz Nowikiewicz, Wojciech Zegarski, Konrad Pagacz, Maciej Nowacki, Alina Morawiec ‐Sztandera, Iwona Głowacka‐Mrotek, Magdalena Sowa, Marta Biedka, Agnieszka Kołacińska Tags: ORIGINAL ARTICLE Source Type: research
The case for the omission of axillary staging in invasive breast carcinoma that exhibits a predominant tubular growth pattern on preoperative biopsy
Abstract
True invasive tubular breast carcinoma (TBC) is unlikely to metastasize to axillary nodes, yet it is routinely subjected to sentinel lymph node biopsy (SLNB), even if the diagnosis was suspected preoperatively. The positive predictive value (PPV) of core biopsy for TBC and the incidence and predictors of axillary metastasis in invasive breast carcinomas identified as tubular‐rich on core biopsy are unknown. Prospective patient and tumor data regarding postoperatively confirmed TBCs, and tubular‐rich carcinoma identified on preoperative core biopsy between January 2005 and May 2016 was analyzed retrospectively....
Source: The Breast Journal - February 24, 2018 Category: Cancer & Oncology Authors: Saed Ramzi, Elaine L. Hyett, Abigail S. Wheal, Peter J. Cant Tags: ORIGINAL ARTICLE Source Type: research
Clinicopathologic analysis of a large series of microinvasive breast cancers
The objective of this study was to determine the rate and predictors of lymph node metastases, recurrence, and survival in a large series of Tmic breast carcinomas. Consecutive cases of Tmic were identified within our health care system from 2001 to 2015. We reviewed results of lymph node sampling and other pathologic factors including hormone receptor/HER2 status, associated in situ tumor size/grade, margin status, number of invasive foci, surgical/adjuvant therapies, and recurrence/survival outcomes. In this cohort, 294 Tmic cases were identified with mean follow‐up of 4.6 years. Of 260 patients who underwent axillar...
Source: The Breast Journal - February 24, 2018 Category: Cancer & Oncology Authors: Tamera J. Lillemoe, Michaela L. Tsai, Karen K. Swenson, Barbara Susnik, Janet Krueger, Kendra Harris, Natasha Rueth, Erin Grimm, Joseph W. Leach Tags: ORIGINAL ARTICLE Source Type: research
Poorly differentiated neuroendocrine carcinoma of the breast with Merkel cell features
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - February 19, 2018 Category: Cancer & Oncology Source Type: research
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The Breast Journal, Ahead of Print. (Source: The Breast Journal)
Source: The Breast Journal - February 19, 2018 Category: Cancer & Oncology Source Type: research
Single arm phase II study of oral vitamin B12 for the treatment of musculoskeletal symptoms associated with aromatase inhibitors in women with early stage breast cancer
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - February 14, 2018 Category: Cancer & Oncology Source Type: research
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The Breast Journal, Ahead of Print. (Source: The Breast Journal)
Source: The Breast Journal - February 14, 2018 Category: Cancer & Oncology Source Type: research
Successful cryoablation of breast cancer
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - February 7, 2018 Category: Cancer & Oncology Source Type: research
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The Breast Journal, Ahead of Print. (Source: The Breast Journal)
Source: The Breast Journal - February 7, 2018 Category: Cancer & Oncology Source Type: research
Cleft nipple: A rare congenital breast anomaly
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - January 22, 2018 Category: Cancer & Oncology Source Type: research
Contribution of intraoperative radiotherapy (IORT) for therapeutic de ‐escalation in early breast cancer: Report of a single institution's experience
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - January 22, 2018 Category: Cancer & Oncology Source Type: research
Hidden estrogen production from ovarian remnants leading to progression of disease in metastatic breast cancer
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - January 22, 2018 Category: Cancer & Oncology Source Type: research
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The Breast Journal, Ahead of Print. (Source: The Breast Journal)
Source: The Breast Journal - January 22, 2018 Category: Cancer & Oncology Source Type: research
