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Dupilumab for atopic dermatitis in children with idiopathic nephrotic syndrome treated with cyclosporin: a report of two cases
Australas J Dermatol. 2024 Feb 29. doi: 10.1111/ajd.14236. Online ahead of print.NO ABSTRACTPMID:38421886 | DOI:10.1111/ajd.14236 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Marcelo B Lucca Julia K Recuero Daniel Lorenzini Magda B Weber Source Type: research

Treatment of lichen planopilaris with Janus kinase inhibitors
Australas J Dermatol. 2024 Feb 29. doi: 10.1111/ajd.14240. Online ahead of print.NO ABSTRACTPMID:38421900 | DOI:10.1111/ajd.14240 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Gabriela A Gonzalez Matheus Kiarash Khosrotehrani Source Type: research

Lower limb lymphangioma circumscriptum: The guiding sign for the diagnosis of Maffucci syndrome
Australas J Dermatol. 2024 Feb 28. doi: 10.1111/ajd.14229. Online ahead of print.NO ABSTRACTPMID:38419154 | DOI:10.1111/ajd.14229 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Álvaro Martínez-Doménech Altea Esteve-Mart ínez Gemma P érez-Pastor Jose Luis S ánchez-Carazo Amparo P érez-Ferriols Source Type: research

Terra firma-forme dermatosis displays bright blue plaques in Ultraviolet-Induced Fluorescence Dermatoscopy
Australas J Dermatol. 2024 Feb 28. doi: 10.1111/ajd.14233. Online ahead of print.NO ABSTRACTPMID:38419181 | DOI:10.1111/ajd.14233 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Katarzyna Korecka Anna S łomiak-Wąsik Aleksandra Da ńczak-Pazdrowska Ryszard Żaba Adriana Pola ńska Source Type: research

Successful infliximab treatment in siblings with Netherton syndrome: Unveiling a novel SPINK5 gene variant and literature review
Australas J Dermatol. 2024 Feb 28. doi: 10.1111/ajd.14234. Online ahead of print.ABSTRACTNetherton syndrome (NS) is a rare autosomal recessive genodermatosis. In this article, we present two siblings with NS who harbour a novel variant in the SPINK5 gene and were treated with infliximab infusions. Both patients exhibited the characteristic clinical triad of NS, and their whole exome sequencing analysis revealed a homozygous variant, c.1820+53G>A, in the SPINK5 gene. Notably, this is the first documented instance of homozygosity for this particular variant. Despite the absence of a specific treatment, both patients achie...
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Nazmiye Selin Salici Adil Ozcanli Gunel Rasulova Ayse Nazli Basak Seyma Tekgul Secil Vural Source Type: research

Minimum labelling requirements for dermatology artificial intelligence-based Software as Medical Device (SaMD): A consensus statement
CONCLUSIONS: This study provides critical evidence for setting labelling standards by the Therapeutic Goods Administration to safeguard patients, health professionals, consumers, industry, and regulatory bodies from AI-based dermatology SaMDs that do not currently provide adequate information about how they were developed and tested.PMID:38419186 | DOI:10.1111/ajd.14222 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Åsa Ingvar Ayooluwatomiwa Oloruntoba Maithili Sashindranath Robert Miller H Peter Soyer Pascale Guitera Tony Caccetta Stephen Shumack Lisa Abbott Chris Arnold Craig Lawn Alison Button-Sloan Monika Janda Victoria Mar Source Type: research

Investigating causal relationships between the gut microbiota and inflammatory skin diseases: A Mendelian randomization study
CONCLUSION: Our study revealed that some gut microbiota are risk factors for inflammatory skin diseases, providing new information on potential therapeutic targets. Additionally, a possible association with the gut-skin axis was confirmed. Further research is required to elucidate the mechanisms underlying these relationships.PMID:38419189 | DOI:10.1111/ajd.14231 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Yunfan Gu Weiming Zhang Wenting Zhao Xianyu Zeng Source Type: research

Adult genital psoriasis: An updated review for clinicians
Australas J Dermatol. 2024 Feb 28. doi: 10.1111/ajd.14227. Online ahead of print.ABSTRACTGenital psoriasis is a chronic inflammatory skin condition that has been reported in up to 63% of patients with psoriasis on other parts of their skin. It has a profound impact on quality of life and sexual function which is often overlooked by current severity scores. Despite its prevalence and disease burden, genital psoriasis remains largely under-reported and under-treated. Historically, this was due to the impracticality and limited efficacy data of standard psoriasis treatments when applied to genital skin. However, there have be...
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Michelle Wu Gayle Fischer Source Type: research

Aquagenic pruritus successfully treated with upadacitinib
Australas J Dermatol. 2024 Feb 28. doi: 10.1111/ajd.14228. Online ahead of print.NO ABSTRACTPMID:38419197 | DOI:10.1111/ajd.14228 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Rodrigo Pe ñuelas Leal Carolina Labrandero Hoyos Andr és Grau Echevarría Javier Lorca Sprohnle Andr és Casanova Esquembre Daniel Blaya Imbernon Malena Finello Violeta Zaragoza Ninet Source Type: research

Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars
CONCLUSIONS: These findings suggest that as inflammatory acne lesions progress, inflammation gradually infiltrates the pilosebaceous unit and affects the resident stem cells. This disruption impedes the normal regeneration of the interfollicular epidermis and adnexal structures, resulting in atrophic acne scars.PMID:38419202 | DOI:10.1111/ajd.14224 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Dong Hyo Kim Ji Young Yoon Jun Hyo Lee Dae Hun Suh Source Type: research

Alterations in gut microbiome associated with severity of atopic dermatitis in infants
CONCLUSION: Discrepancies in gut microbial composition and functional pathways were observed in infants with mild-to-severe AD. Alterations in butyrate-producing bacteria (Clostridium sensu stricto), sphingolipid-producing bacteria (Parabacteroides, Bacteroides), and related functional pathways were associated with the severity of AD infants.PMID:38419203 | DOI:10.1111/ajd.14237 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 29, 2024 Category: Dermatology Authors: Xiaoyi Liu Meiqin Cai Meiru Chen Ji Chen Tingyu Zhu Shiyin Wu Jie Jia Source Type: research

Self-reported clinical features and treatment effectiveness of Papillon-Lef èvre syndrome patients from five Latin American countries: A cross-sectional online survey study
CONCLUSIONS: The study's results align with prior research on PLS, but reveal new insights, including the impact on patients' quality of life and a history of delayed umbilical cord separation. These findings warrant consideration in future research and patient care.PMID:38351550 | DOI:10.1111/ajd.14219 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 14, 2024 Category: Dermatology Authors: Daniela Alfaro-Sep úlveda P ía Parra Salinas Fernando Valenzuela Carmen Gloria Gonzalez Valentina Burckhardt-Bravo Dominga Ferrari-Sande Source Type: research