Factors Associated with Long COVID: Insights from Two Nationwide Surveys
: Long COVID is a multisystemic condition that affects the lives of millions of people globally, yet factors associated with it are poorly defined. Our purpose in this study was to identify factors associated with long COVID. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 13, 2024 Category: General Medicine Authors: Yixuan Wu, Mitsuaki Sawano, Yilun Wu, Rishi M. Shah, Pamela Bishop, Akiko Iwasaki, Harlan M. Krumholz Tags: Clinical Research Study Source Type: research
How investigative reporting and the “fourth estate” saved hypertrophic cardiomyopathy…twice
Hypertrophic cardiomyopathy is a complex, often inherited, and heterogeneous cardiac disease once characterized by grim prognosis with limited treatment options1. However, contemporary management has dramatically altered clinical course resulting in greatly reduced hypertrophic cardiomyopathy-related mortality1. It is notable that these important clinical advances were aided on 2 occasions by aggressive involvement of the U.S. press and print media (sometimes referred to as the “Fourth Estate”)12,3. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 13, 2024 Category: General Medicine Authors: Barry J. Maron Tags: Commentary Source Type: research
High-Sensitivity Cardiac Troponins in Patients with Chest Pain and Treatment With Oral Antineoplastic Agents Associated With Cardiovascular Toxicity
Oral antineoplastic agents are more commonly being used in the treatment of cancer, and a wide range of cardiovascular adverse effects associated with these treatments are being reported with increasing frequency, including hypertension, left ventricular (LV) dysfunction and arrhythmias.1 –3 Although no recommendations on measurements of cardiac biomarkers specifically in the setting of oral agents exists, a growing evidence support the use of cardiac troponins (cTn) during chemotherapy for early identification and monitoring of drug-induced cardiovascular toxicity. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 13, 2024 Category: General Medicine Authors: Andreas Roos, Gustaf Edgren Tags: Clinical Research Study Source Type: research
Guidance for healthcare providers on newest guidelines for over-the-counter drug treatment of mild symptoms of COVID-19. (word count=18; limit=20)
On January 18, 2024, the United States (US) Centers for Disease Control and Prevention (CDC)1 issued their most recent guidelines for over the counter drugs for COVID-19, stating “Most people with COVID-19 have mild illness and can recover at home. You can treat symptoms with over-the-counter medicines, such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil), to help you feel better.” (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 12, 2024 Category: General Medicine Authors: Gage Collamore, Mark J. DiCorcia, Yash Nagpal, Lawrence Fiedler, Michael A. Garone, David L. DeMets, Dennis G. Maki, Charles H. Hennekens Tags: Review Source Type: research
A Critical Review on the Long-term COVID-19 Impacts on Patients with Diabetes
The world is currently grappling with the potentially life-threatening coronavirus disease 2019 (COVID-19), marking it as the most severe health crisis in the modern era. COVID-19 has led to a pandemic, with the World Health Organization (WHO) predicting that individuals with diabetes are at a higher risk of contracting the virus compared to the general population. This review aims to provide a practical summary of the long-term impacts of COVID-19 on patients with diabetes. Specifically, it focuses on the effects of SARS-CoV-2 on different types of diabetic patients, the associated mortality rate, the underlying mechanism...
Source: The American Journal of Medicine - March 12, 2024 Category: General Medicine Authors: Sumel Ashique, Neeraj Mishra, Ashish Garg, Sweta Garg, Arshad Farid, Shweta Rai, Gaurav Gupta, Dua Kamal, Keshav Raj Paudel, Farzad Taghizadeh-Hesary Tags: Clinical Research Study Source Type: research
Smoking and respiratory diseases in patients with coronary microvascular dysfunction
Coronary microvascular disease (CMD) is common in patients with and without obstructive coronary artery disease, and is associated with adverse clinical outcomes. Respiratory-related variables are associated with pulmonary and systemic microvascular dysfunction, while evidence regarding their relationship with CMD is limited. We aim to evaluate respiratory-related variables as risk factors of CMD. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 12, 2024 Category: General Medicine Authors: Ophir Freund, Aviel Shetrit, Amir Bar-Shai, Lior Zornitzki, Shir Frydman, Ariel Banai, Reut Amar Shamir, Jeremy Ben-Shoshan, Yaron Arbel, Shmuel Banai, Maayan Konigstein Tags: Clinical Research Study Source Type: research
Massive splenomegaly with thrombotic infarction as an initial manifestation of triple diagnosis
A 43-year-old female was admitted to our clinic with complaints of fatigue, fever, and sudden pain in the left upper abdomen. The patient's medical history was unremarkable. Physical examination revealed an enlarged spleen with pain upon palpation. Blood tests showed severe macrocytic anemia with hemoglobin:3.9 g/dL and mean corpuscular value of 97 (reference range: 80-95), increased C-reactive protein level of 111 mg/L (reference range:0-5), lactate dehydrogenase levels of 533 U/L (reference range: 135-250) and hyperbilirubinemia rate of 2,2 mg/dL (reference range:0,2-1,2). (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 12, 2024 Category: General Medicine Authors: Merve Guzel Dirim, Onur Duman, Naci Senkal, Alpay Medetalibeyoglu, Murat Kose Tags: Clinical Communication to the Editor Source Type: research
Re-emergence of Childhood Restless Legs Syndrome in Adulthood following COVID-19 infection
Restless legs syndrome (RLS), also referred to as Willis-Ekbom Disease, has a prevalence between 1 and 15% in various populations, and affects 2% of children (1). (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 12, 2024 Category: General Medicine Authors: Brendan Jen-Wei Tan, Yew-Long Lo, Ling-Ling Chan, Eng-King Tan Tags: Clinical Communication to the Editor Source Type: research
Giant hepatic cyst
To the Editor: (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 11, 2024 Category: General Medicine Authors: Ai Yokoi, Kosuke Ishizuka, Iori Motohashi, Masaki Hiwatari, Takashi Asakura, Kenya Ie Tags: Clinical Communication to the Editor Source Type: research
Complications of Radial vs Femoral Access For Coronary Angiography and Intervention: What Do The Data Tell Us?
In the last decades, radial access, as an alternative to femoral access, has rapidly evolved and emerged as the preferred vascular access for coronary angiography and percutaneous coronary intervention (PCI). The use of radial access for PCI can reduce access-site bleeding, particularly retroperitoneal bleeding, and risk of developing pseudoaneurysm, while also improving patient comfort after procedure (e.g., early ambulation). However, radial access requires a longer learning curve to develop technical skills and the the data on radial artery graft for coronary artery bypass graft (CABG) after radial access remain unknown...
Source: The American Journal of Medicine - March 7, 2024 Category: General Medicine Authors: Chayakrit Krittanawong, Lakshmi Uppalapati, Hafeez Ul Hassan Virk, Yusuf Kamran Qadeer, Umer Irshad, Zhen Wang, Samin Sharma, Hani Jneid Tags: Review Source Type: research
Should All Application Materials Be Made Equal? A Plea for Individuality
We have read and discussed the article by Machen et al1 discussing equity and bias in letters of recommendation. While we agree with the overall goal to reduce bias and promote equity in the residency application process, the suggested approach to standardization of letters of recommendation (LORs) may limit the purpose and information that can be derived from an LOR. With the movement to standardize multiple components of the application including transitioning to pass/fail of Step 1 and medical school clerkships, we argue that LORs play a unique role in highlighting aspects of the applicant's integrity and values that ca...
Source: The American Journal of Medicine - February 28, 2024 Category: General Medicine Authors: Robert M. Krahmer, Kiranpreet Kaur, Cassandra A. Gross, Harold Paul Tags: Letter Source Type: research
Which Was the Real Guilty Party: Staphylococcus aureus, Staphylococcus pseudintermedius, Pasteurella multocida or All of Them?
I read with great interest the case report of McPherson et al1 that recently appeared in your Journal. They reported a case of epicardial abscess in a relatively immunocompetent patient. Abscess culture yielded Pasteurella multocida, which was identified as the causative agent. Previously obtained blood cultures yielded Staphylococcus aureus and Staphylococcus pseudintermedius. I have a few comments regarding the causative agent(s) of epicardial abscess in this case. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - February 28, 2024 Category: General Medicine Authors: Hasan Tahsin Gozdas Tags: Letter Source Type: research
Advancing Predictive Models for Atrial Fibrillation Onset: A Critique and Path Forward
I read with great interest the recent article by Ying Gue, MB et al.1 While the research provides valuable insights into the predictors of atrial fibrillation in heart failure patients, there are several aspects that warrant further attention and improvement. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - February 28, 2024 Category: General Medicine Authors: Angel Sebastian Trevi ño-Juarez Tags: Letter Source Type: research
The Reply
We thank Dr. Krahmer, Dr. Kaur, Dr. Gross, and Dr. Paul for their thoughtful response to our article.1 We wholeheartedly agree with their statement that letters of recommendation (LORs) “play a unique role in highlighting aspects of the applicant's integrity and values that cannot be gleaned from the CV, list of publications, or list of awards earned.” To clarify, we do not wish to replace narrative LORs with standardized letters of evaluation, such as those used by Emergency M edicine.2 We believe there is no substitute for the narrative LOR and we are suggesting a general structure. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - February 28, 2024 Category: General Medicine Authors: Julie L. Machen, Saurin M. Gandhi, Christopher J. Moreland, Sherine Salib Tags: Letter Source Type: research
The Reply
We thank Dr Gozdas for his comments on our case report of an epicardial abscess involving Pasteurella multocida in a relatively immunocompetent patient.1 Dr Gozdas points out that because wound infections related to canine exposure are often polymicrobial, the fact that our patient's blood cultures grew Staphylococcus aureus and Staphylococcus pseudintermedius may be indicative of a polymicrobial cardiac abscess rather than solely due to P. multocida. Dr Gozdas further points out that the three organisms (S. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - February 28, 2024 Category: General Medicine Authors: Sanjay V. Menghani, Rina G. Bhalodi, David F. McPherson, Torey A. Roesch Tags: Letter Source Type: research
