Table of Contents
(Source: The American Journal of Medicine)
Source: The American Journal of Medicine - May 1, 2022 Category: General Medicine Source Type: research

The Reply
We welcome the opportunity to address Dr Reinharth's letter because it gives us a chance to also reply to the many appreciative emails we received about our article.1 It seems to have touched a chord —or a nerve. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - May 1, 2022 Category: General Medicine Authors: Salvatore Mangione, Brian F. Mandell, Stephen G. Post Tags: Letter Source Type: research

AAIM Recommendations to Promote Equity in the Clerkship Clinical Learning Environment
Despite widespread recognition of inequities related to gender, race, and ethnicity in undergraduate medical education (UME), effective solutions have been difficult to identify. In this perspective, the Alliance for Academic Internal Medicine (AAIM) focuses on issues specific to the clerkship clinical learning environment (CCLE). (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 30, 2022 Category: General Medicine Authors: Amber T. Pincavage, Nora Y. Osman, Irene Alexandraki, Nadia J. Ismail, Diane L. Levine, Chavon M. Onumah, Cindy J. Lai Source Type: research

Disparities in Representation of Women, Older Adults, and Racial/Ethnic Minorities in Immune Checkpoint Inhibitor Trials
We aim to describe reporting and representation of minority patient populations in immune checkpoint inhibitor (ICI) clinical trials and assess predictors of enrollment disparity. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 25, 2022 Category: General Medicine Authors: Irbaz B. Riaz, Mahnoor Islam, Ahsan Masood Khan, Syed Arsalan Ahmed Naqvi, Rabbia Siddiqi, Kaneez Zahra Rubab Khakwani, Noureen Asghar, Waleed Ikram, Syed A. Hussain, Parminder Singh, Jeremy L. Warner, Guru P. Sonpavde, Folakemi T. Odedina, Kenneth L. Keh Tags: Clinical Research Study Source Type: research

Disparities in Representation of Women, Older Adults and Racial/Ethnic Minorities in Immune Checkpoint Inhibitor Trials
We aim to describe reporting and representation of minority patient populations in immune checkpoint inhibitor (ICI) clinical trials and assess predictors of enrollment disparity. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 25, 2022 Category: General Medicine Authors: Irbaz B. Riaz, Mahnoor Islam, Ahsan Masood Khan, Syed Arsalan Ahmed Naqvi, Rabbia Siddiqi, Kaneez Zahra Rubab Khakwani, Noureen Asghar, Waleed Ikram, Syed A. Hussain, Parminder Singh, Jeremy L. Warner, Guru P. Sonpavde, Folakemi T. Odedina, Kenneth L. Keh Tags: Clinical research study Source Type: research

Burden of Microvascular Disease and Risk of Atrial Fibrillation in Adults with Type 2 Diabetes
Epidemiological data on the associations of microvascular disease with atrial fibrillation are scarce. We evaluated the associations of diabetes-related microvascular disease in multiple vascular beds and its burden with incident atrial fibrillation among adults with type 2 diabetes. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 25, 2022 Category: General Medicine Authors: Arnaud D. Kaze, Matthew F. Yuyun, Gregg C. Fonarow, Justin B. Echouffo-Tcheugui Source Type: research

Crowned Dens Syndrome Presenting as Altered Mental Status
A 77-year-old male presented from a rehabilitation facility for acute onset of confusion, significant pain in his neck and extremities, muscle rigidity and subjective fever. Co-morbidities included Parkinson's disease, Lewy Body Dementia, anxiety, depression and recent right shoulder surgery complicated by pulmonary embolism, for which he was started on Eliquis. On admission, physical exam revealed severely limited range of motion in neck, diffuse rigidity and weakness in all extremities, diffuse joint pain with movement of extremities and neck, and disorientation. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 24, 2022 Category: General Medicine Authors: Joshua Lee, Jonathan Cheah, Prakash Paudel Tags: Clinical Communication to the Editor Source Type: research

The Effect of Hospital Visitor Policies on Patients, Their Visitors, and Health Care Providers During the COVID-19 Pandemic: A Systematic Review
Health care policymaking during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has questioned the precedent of restricting hospital visitors. We aimed to synthesize available data describing the resulting impact on patient, family/visitor, and health care provider well-being. We systematically reviewed articles from the World Health Organization COVID-19 Global Literature on Coronavirus Disease Database published between December 2019 through April 2021. Included studies focused on hospitalized patients and reported 1 or more prespecified main or secondary outcome (coronavirus disease 2019 [COVID...
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Audra N. Iness, Jefferson O. Abaricia, Wendemi Sawadogo, Caleb M. Iness, Max Duesberg, John Cyrus, Vinay Prasad Tags: Review Source Type: research

Do Hospital Visit Restrictions Cause Increase in the Doses of Morphine in Terminal Care? Spiritual Pain and Palliative Care in the COVID-19 Pandemic
The Centers for Disease Control and Prevention (CDC) alerted public health departments, health care professionals, and first responders of “a concerning acceleration of the increase in drug overdose deaths” coinciding with the emergence of the coronavirus disease 2019 (COVID-19) pandemic and said that the surge in deaths was driven primarily by a rapid rise in overdose deaths caused by synthetic opioids.1 (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Hiroshi Kudo, Chieko Miyata, Yoshiki Kawaguchi, Yutaka Yachi, Masaki Shinfuku, Takayuki Kinoshita, Tomohiro Kurihara, Yukihiko Momiyama, Tonghyo Chong, Yoshiro Kobayashi, Mihiro Takazawa, Kenji Itoh, Koichi Tsunoda Tags: Commentary Source Type: research

Do hospital visit restrictions cause increase in the doses of morphine in terminal care?-Spiritual pain and palliative care in the COVID-19 pandemic-
The Centers for Disease Control and Prevention (CDC) has alerted public health departments, health care professionals, and first responders of “a concerning acceleration of the increase in drug overdose deaths” coinciding with the emergence of the coronavirus disease 2019 (COVID-19) pandemic and has said that the surge in deaths was driven primarily by a rapid rise in overdose deaths caused by synthetic opioids.1 (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Hiroshi Kudo, Chieko Miyata, Yoshiki Kawaguchi, Yutaka Yachi, Masaki Shinfuku, Takayuki Kinoshita, Tomohiro Kurihara, Yukihiko Momiyama, Tonghyo Chong, Yoshiro Kobayashi, Mihiro Takazawa, Kenji Itoh, Koichi Tsunoda Source Type: research

The Two Pandemics
In Heart Transplant Clinic, her first words were always, “How are the kids?” In the ten years since her transplant, she had delighted in my three pregnancies and admired the babies I toted around at transplant holiday parties. But at this visit, her first words were, “You're from India, right?” (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Michelle M Kittleson Source Type: research

Management of Hospitalized Kidney Transplant Recipients for Hospitalists and Internists
The number of kidney transplant recipients have grown incrementally over the years. These patients have a high comorbidity index and require special attention to immunosuppression management. In addition, this population has an increased risk for cardiovascular events, electrolyte abnormalities, allograft dysfunction and infectious complications. . It is vital for hospitalists and internists to understand the risks and nuances in the care of this increasingly prevalent but also high-risk population. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Sam Kant, Sandeep Soman, Michael J. Choi, Bernard G. Jaar, Deborah B. Adey, National Kidney Foundation Education Committee Source Type: research

Ghost of Summer, 1988
He was Admission Number Five from the emergency department during the last week of June 1988. I learned of him through the triage resident, who said he was an easy admission, and for an inefficient Day 3 intern like me, he was something like a gift. I was told that he had uremia due to HIV nephropathy but was not a dialysis candidate; however, that brief case summary would fail to convey his full significance for me. I found him supine on a gurney, cachectic and delirious, his brown skin marked by severe eczema – and we were the same age. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Richard Scott Morehead Tags: Medical Humanities Source Type: research

Temporal Trends in Racial and Ethnic Disparities in Multimorbidity Prevalence in the United States, 1999 –2018
In 2010, the US Department of Health and Human Services published a public health framework for managing patients with multimorbidity, defined as the presence of two or more concurrent chronic conditions in an individual, highlighting the importance of identifying and addressing disparities in its prevalence.1,2 The overall prevalence is increasing in the US. Moreover, studies indicate that multimorbidity is more prevalent among Black people compared with White people, even though race, a social construct, has no intrinsic relationship with morbidity risk. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: C ésar Caraballo, Jeph Herrin, Shiwani Mahajan, Daisy Massey, Yuan Lu, Chima D. Ndumele, Elizabeth E. Drye, Harlan M. Krumholz Tags: Clinical Research Study Source Type: research

Rates of In-hospital Decongestion and Association with Mortality and Cardiovascular Outcomes among Patients admitted for Acute Heart Failure
Decongestion is an important goal in the management of acute heart failure. Whether the rate of decongestion is associated with mortality and cardiovascular outcomes is unknown. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2022 Category: General Medicine Authors: Wendy McCallum, Hocine Tighiouart, Jeffrey M. Testani, Matthew Griffin, Marvin A. Konstam, James E. Udelson, Mark J. Sarnak Tags: Clinical Research Study Source Type: research