Comprehensive Evidence-based Health Maintenance
The potential of primary prevention to prevent, delay, or ameliorate disease is immense. However, the total spending on preventive services in the US remains astoundingly small and represents a meager 3.5% of total health care spending. Moreover, training focused on prevention in medical schools is often neglected, and time-constrained primary providers frequently omit effective preventive and early detection measures, or perform them perfunctorily. Indeed, preventable conditions of serious consequences including ‘premature’ mortality, cardiovascular events, and major organ failure are ubiquitous with the global obesit...
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Ami Schattner Tags: Review Source Type: research

Ischemic stroke caused by bilateral internal carotid artery dissection due to elongated styloid processes: A case report
A 50-year old male was admitted to our hospital because of "dizziness with left limb fatigue for 12 hours"; After considering both the patient's medical history and imaging results, it was determined that the patient's bilateral internal carotid artery dissection was caused by bilateral elongated styloid processes, so the patient was underwent bilateral styloid process truncation via the intraoral route under general anesthesia. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Yan Luo, Yongjun Cao, Zhongsheng Cao, Dai Shi, Jijun Shi Tags: Diagnostic Dilemma Source Type: research

Serial Home Blood Pressure and Heart Rate Measurements for Optimized Management
Serial blood pressure and heart rate measurements, particularly obtained by the patents at home, are currently recommended for the management of patients. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: John E. Madias Tags: Brief Observation Source Type: research

A Hidden Challenge: Tongue Abscess Inducing Trismus in an Older Woman
A 78-year-old female with no significant medical history presented to the emergency department complaining of jaw pain and trismus (lockjaw). Two weeks prior to admission, a lower right denture was inserted during a dental procedure. Subsequently, she gradually developed bilateral lower jaw pain and trismus. Five days prior to admission, she consulted an oral surgeon and was initially diagnosed with bilateral temporomandibular joint disorder. Two days prior to admission, the pain in her left jaw and trismus worsened, leading to inability to eat or drink orally. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Yuhei Kuriyama, Kazuya Nagasaki, Naoki Iso, Hiroyuki Kobayashi Tags: Diagnostic Dilemma Source Type: research

Adult Scaphoid Abdomen
To the Editor: (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Joanna L. Langner, Gregory B. Seymann Tags: Clinical Communication to the Editor Source Type: research

Septic arthritis of the costovertebral joint mimicking shingles
To the Editor (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Yoshinori Tateishi, Rentaro Oda Tags: Clinical Communication to the Editor Source Type: research

Patterns of Statin Therapy Use and Associated Outcomes in Older Veterans Across Kidney Function
The objective of this analysis was to evaluate the effect of initiating statin therapy on incident dementia and mortality among individuals 75 years of age or older across the complete spectrum of kidney function. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 2, 2024 Category: General Medicine Authors: Grenita Gjyriqi, Adam Gross, Edith Burns, Eugenia Gianos, Mandeep Sidhu, Roy Mathew Tags: Clinical Research Study Source Type: research

Navigating the Shadows: COVID-19 ′s Lingering Threat – Pulmonary Fibrosis
Pulmonary fibrosis has long been associated with significant morbidity. Yet, the precise relationship between coronavirus disease 2019 (COVID-19) and this debilitating condition has remained relatively uncharted territory. A study by Najjar-Debbiny et al1 followed a cohort of 2,894,801 adults for the occurrence of pulmonary fibrosis from May 1, 2020, to June 30, 2022. Individuals who had experienced COVID-19 were found to have an increased risk of pulmonary fibrosis, with an odds ratio of 1.80 compared with those who had not contracted the virus. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Authors: Chia Siang Kow, Dinesh Sangarran Ramachandram, Syed Shahzad Hasan, Kaeshaelya Thiruchelvam Tags: Letter Source Type: research

Integrating HEAR Score and Troponin: Are We Evaluating All the Potential Utilities?
We read with great interest the study by Ola et al1 about the efficacy of HEAR (History, Electrocardiogram, Age, Risk factors) score in the emergency department. We commend the authors for successfully integrating high-sensitivity cardiac troponin T (hs-cTnT) with a newly proposed risk stratification tool for evaluating patients with acute chest pain, one of the most common and important chief complaints in the emergency department. However, certain factors should be considered prior to incorporating their findings into the ongoing debate on HEAR score. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Authors: Takuma Ishibashi, Akira Yamaguchi, Wataru Horiguchi, Takumi Sato, Hiroshi Ito, Tomonari Shimoda Tags: Letter Source Type: research

Terminological Insights in Ludwig Angina: Evaluating Pseudo Tongue, Double Tongue, and Ludwig Sign
We read with interest the manuscript by Minagawa and Nagasaki, on the “double-tongue sign” in Ludwig angina and provide further perspective on the accuracy of this terminology in medical discourse.1 Wilhelm Friedrich von Ludwig, in his 1836 paper “Ueber eine Form von Halsentzündung” (About a form of strep throat), described the oral cavity, neck, and systemic symptoms occurring as an inflammatory superficial and deep-seated soft tissue infection in the submandibular space and less frequently involving the parotid and sublingual glands. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Authors: Steven H. Yale, Halil Tekiner, Eileen S. Yale Tags: Letter Source Type: research

The Reply
We appreciate the insightful letter from Dr. Yale and his colleagues regarding our manuscript, “Double-tongue sign in Ludwig's angina.”1 We value the depth of their understanding and the historical context they have provided. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Authors: Shun Minagawa, Kazuya Nagasaki Tags: Letter Source Type: research

The Reply
We thank Ishibashi and their colleagues for their interest in our recent publication on the use of the HEAR score and high-sensitivity troponin T assay for risk stratification of emergency department patients presenting with suspected acute coronary syndrome.1 It provides us with an opportunity to make the goal of our study clear. Our work sought to apply the recommendation from the 2021 AHA/ACC chest pain guidelines2 suggesting that risk stratification using the HEAR score be used after possible myocardial infarction has been diagnosed or excluded. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Authors: Olatunde Ola, Yader Sandoval, Allan S. Jaffe Tags: Letter Source Type: research

Comments on Whether Physicians and Nurses Should Sit on the Patient's Bed
I read with great interest the recent perspective by Dr Alpert on the bedside sitting by doctors.1 I wholeheartedly praise Dr Alpert for discussing such a tender issue. I would like to further address this topic using anecdotes from my professional journey. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Authors: Ankur Jain Tags: Letter Source Type: research

Table of Contents
(Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 1, 2024 Category: General Medicine Source Type: research

Calculated Medicine: Seven Decades of Accelerating Growth
This article reviews the history and varied methodologies of Calculated Medicine starting with the 1953 Apgar Score and concluding with a look into modern computational tools of the field: machine learning, natural language processing, artificial intelligence, and in silico research techniques. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - March 29, 2024 Category: General Medicine Authors: Louis E. Leff, Mara L. Koperwas Tags: Review Source Type: research