Antiphospholipid antibody syndrome unmasked: A rare cause of recurrent early coronary stent thrombosis
All authors have participated in the preparation of the manuscript. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 23, 2023 Category: General Medicine Authors: Syed Bukhari, Mohamed Ghoweba, Douglas Joseph Tags: Diagnostic Dilemma Source Type: research

Claw Hand Deformity in Leprosy
: No funding or sponsorship was received for any aspect of this article, including design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 22, 2023 Category: General Medicine Authors: Grant Z Zhao, Samantha Venkatesh, Lida Zheng, Cuong V Nguyen Tags: DERM Images in Dermatology Source Type: research

Shark Fin Sign
A 51-year-old man with a history of diabetes mellitus and chronic kidney disease presented with sudden onset of chest pain and dyspnea for one hour. He had no remarkable smoking or cardiac family history. The patient was barely conscious at the time of the paramedic's contact, but his Glasgow Coma Scale was 3 on arrival at the hospital. A 12 ‐lead electrocardiogram (ECG) demonstrated a wide complex rhythm with “shark fin” morphology in leads I, aVR, aVL, and the precordial leads (Fig. A). Shortly after the ECG was taken, he went into cardiopulmonary arrest. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 22, 2023 Category: General Medicine Authors: Ryohei Ono, Togo Iwahana, Hirotoshi Kato, Kaoruko Aoki, Yoshio Kobayashi Tags: Clinical Communication to the Editor Source Type: research

Limbic Encephalitis
This is to confirm that all authors had access to the data and a role in writing the manuscript. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 22, 2023 Category: General Medicine Authors: Ami Schattner, Ina Dubin, Livnat Uliel Tags: Clinical Communication to the Editor Source Type: research

Severe headache in a man with a history of migraine: the importance of 'peripheral vision'
cerebral venous sinus thrombosis, magnetic resonance images, cervical lesions, flow void, peripheral vision (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 22, 2023 Category: General Medicine Authors: Akiyuki Hiraga, Kazuho Kojima Tags: Clinical Communication to the Editor Source Type: research

Whose Interests Are Served By Promoting Antidepressants in Patients with Cardiovascular Disease?
The meta-analysis assessing cardiovascular disease among those with major depressive disorder deserves robust comment.1 (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Alain Braillon Tags: Letter Source Type: research

The Reply
We thank Dr Braillon for his interest in our meta-analysis.1 Dr Braillon points out the limitations of the included studies. Indeed, we agree that these are observational studies and cannot imply causality. Most importantly, smoking and heavy alcohol consumption are traditional cardiovascular risk factors and could potentially be confounders. Further prospective randomized clinical trials are urgently needed to determine whether depression could lead to cardiovascular disease. That said, antidepressants should not be used in cardiovascular disease patients without depression. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Chayakrit Krittanawong, Neil Sagar Maitra, Yusuf Kamran Qadeer, Zhen Wang, Sonya Fogg, Eric A. Storch, Christopher M. Celano, Jeff C. Huffman, Manish Jha, Dennis S. Charney, Carl J. Lavie Tags: Letter Source Type: research

Table of Contents
(Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Source Type: research

Potential Utility of Sodium-Glucose Cotransporter-2 Inhibitors in Treating Myocarditis
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors, designed to increase excretion of glucose, are now considered to have pleiotropic effects. These agents have gained increasing popularity for the treatment of heart failure and chronic kidney disease. However, the benefits of using these agents for other cardiac pathologies, such as myocarditis, are not well understood. We are presenting a unique case of a 22-year-old male with myocarditis who responded well to treatment with SGLT-2 inhibitors and other heart failure medications with the intent to discuss its anti-inflammatory and pleiotropic effects. (Source: The America...
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Michael H. Kim, Yash Suri, Iniya Rajendran, J.R. Exequiel T. Pineda Tags: Clinical Communication to the Editor Source Type: research

Antimitochondrial Antibody-Positive Myositis
A 56-year-old Japanese woman presented with a 1-month history of low back and bilateral thigh pain. Symptoms were aggravated by movements like turning or standing. Her medical history was unremarkable. Physical examination revealed a temperature of 37.0 °C, pulse rate of 96 beats per minute, blood pressure of 115/63 mm Hg, respiratory rate of 18 breaths per minute, and SpO2 of 98% (room air). Grasping pain was present in the lumbar back and both thighs, with lumbar lordosis observed in standing posture. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Kosuke Ishizuka, Yoshiyuki Ohira Tags: Clinical Communication to the Editor Source Type: research

Applying the ABCs of Cardiovascular Disease Prevention to the 2023 AHA/ACC Multisociety Chronic Coronary Disease Guidelines
The 2023 American Heart AHA/ACC/Multisociety Guideline for the Management of Patients with Chronic Coronary Disease provides updated recommendations for the management of chronic coronary disease. The term chronic coronary disease reflects the lifelong nature of the disease and diverse disease etiologies that come under the chronic coronary disease umbrella beyond the presence of epicardial coronary stenosis, which require targeted lifestyle recommendations, serial optimization of medications, and involvement of multiple care team members. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Abhishek Gami, Ian Everitt, Roger S. Blumenthal, L. Kristin Newby, Salim S. Virani, Payal Kohli Tags: Review Source Type: research

The Potential Utility of Sodium-glucose Cotransporter-2 Inhibitors in Treating Myocarditis
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors, designed to increase excretion of glucose are now considered to have pleiotropic effects. These agents have gained increasing popularity for the treatment of heart failure and chronic kidney disease. However, the benefits of using these agents for other cardiac pathologies such as myocarditis are not well understood. We are presenting a unique case of a 22-year-old male with myocarditis who responded well to treatment with SGLT-2 inhibitors and other heart failure medications with the intent to discuss its anti-inflammatory and pleiotropic effects. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Michael H. Kim, Yash Suri, Iniya Rajendran, J.R. Exequiel T. Pineda Tags: Clinical Communication to the Editor Source Type: research

Erythema Ab Igne: Decoding Skin Presentations of vasculitis mimickers in Autoimmunity
A female patient in her 50s with systemic lupus erythematosus presented with a widespread eruption on her back, first noticed by her daughter 3 months ago. On initial rheumatologic evaluation, concern was raised for vasculitis or a thrombotic vasculopathy given the reticulated skin discoloration in the setting of systemic lupus erythematosus. She was referred to the Department of Dermatology for evaluation, where physical examination revealed a well-appearing patient with Fitzpatrick Skin Type IV. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Michael G. Buontempo, Vignesh Ramachandran, Daniel R Mazori, Alisa Femia, Michelle Sikora, Kristen Lo Sicco, Avrom S. Caplan Tags: Images in Dermatology Source Type: research

Music and Medicine: Promoting Harmony for Health
Music has been an integral part of human life since the ancient past. As a powerful tool to express emotions, music has been used in the daily life of human beings for relaxation, stress reduction, dance, socialization entertainment, ritual and religious ceremonies.1 (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Niloofar Nobakht, Mohammad Kamgar, Maryam Tavanaei, Robert M. Bilder, Ehsan Nobakht Tags: Review Source Type: research

Anti-mitochondrial antibody-positive myositis
A 56-year-old Japanese woman presented with a 1-month history of low back and bilateral thigh pain. Symptoms are aggravated by movements like turning or standing. Her medical history was unremarkable. Physical examination revealed a temperature of 37.0 °C, pulse rate of 96 beats/minute, blood pressure of 115/63 mmHg, respiratory rate of 18 breaths/minute, and SpO2 of 98% (room air). Grasping pain was present in the lumbar back and both thighs, with lumbar lordosis observed in standing posture. Manual muscle testing indicated proximal muscle stren gth decreased to approximately 4, and an agitated gait was observed. (Source...
Source: The American Journal of Medicine - October 21, 2023 Category: General Medicine Authors: Kosuke Ishizuka, Yoshiyuki Ohira Tags: Clinical Communication to the Editor Source Type: research