Unstable Angina Risk Stratification using High-sensitivity Cardiac Troponin and Coronary Angiography
Patients formerly diagnosed with unstable angina (UA) are being reclassified as non-ST-elevation myocardial infarction (NSTEMI) with the widespread adoption of sensitive troponin assays (hsTn), leading to significant changes in the incidence and prognosis of UA. The main purpose of this study was to evaluate the value of hsTn and the presence of significant obstructive CAD in the risk stratification of patients with unstable angina. We conducted a retrospective, single-centre study of 742 patients hospitalized for UA between 2016-2021. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 3, 2024 Category: Cardiology Authors: Luis Paiva, Maria Jo ão Vieira, Mariana Simões, Maria João Ferreira, Lino Gonçalves Source Type: research
Convolutional Neural Networks To Study Contrast-Enhanced Magnetic Resonance Imaging Based Skeletal Calf Muscle Perfusion In Peripheral Artery Disease
Peripheral artery disease (PAD) is associated with impaired blood flow in the lower extremities and histopathological changes of the skeletal calf muscles resulting in abnormal microvascular perfusion. We studied the use of convolutional neural networks (CNNs) to differentiate PAD patients from matched controls by utilizing perfusion pattern features from contrast-enhanced magnetic resonance imaging (CE-MRI) of the skeletal calf muscles. We acquired CE-MRI based skeletal calf muscle perfusion in 56 individuals (36 PAD patients, 20 matched controls). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 3, 2024 Category: Cardiology Authors: Bijen Khagi, Tatiana Belousova, Christina M. Short, Addison Taylor, Jean Bismuth, Dipan J. Shah, Gerd Brunner Source Type: research
Corrigendum to ‘Reverse Remodeling Effects of Sacubitril-Valsartan: Structural and Functional Optimization in Stage C Heart Failure’ [American Journal of Cardiology 210 (2024) 249-255]
The authors apologize for the misspelling of co-author Dr. Kalantari's name. The manuscript has been corrected. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 2, 2024 Category: Cardiology Authors: Sara Kalantari, Daniel Oren, Diego Medvedofsky, Akhil Narang, Teruhiko Imamura, Sarah Tayazime, Gene H. Kim, Jayant Raikhelkar, Gabriel Sayer, Roberto M. Lang, Nir Uriel Tags: Corrigendum Source Type: research
Editorial Board
(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 31, 2024 Category: Cardiology Source Type: research
Contents
(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 31, 2024 Category: Cardiology Source Type: research
PRECISE-DAPT, ARC-HBR, or Simplified Clinical Evaluation for the Prediction of Major Bleeding After Percutaneous Coronary Intervention in Elderly Patients
Elderly patients have been remarkably underrepresented in bleeding risk cohorts. Thus, the PRECISE-DAPT and Academic Research Consortium for High Bleeding Risk (ARC-HBR) scores are not validated in older adults. Therefore, we sought to evaluate the PRECISE-DAPT and ARC-HBR scores in an exclusively elderly population and assess the prognostic value of a truly simplified clinical evaluation (SCE), consisting of only 3 binary clinical variables (hemoglobin (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 27, 2024 Category: Cardiology Authors: Alexander Felix Marschall, Juan Duarte Torres, Bel én Biscotti Rodíl, Inés Gómez Sánchez, Elena Basabe Velasco, Carmen Ramos Alejos-Pita, Edurne López Soberón, Alfonso Suárez Cuervo, Salvador Álvarez Antón, Jose María de la Torre Hernández, Da Source Type: research
It Is Time to Overcome the “One-Size-Fits-All” Approach in Chronic Coronary Syndrome?
Chronic coronary syndrome (CCS) refers to a wide spectrum of clinical conditions characterized by clinically stable progression of coronary artery disease (CAD).1 Current guidelines recommend the administration of dual antiplatelet therapy (DAPT) with cardioaspirin and clopidogrel for 6 months for patients who underwent elective percutaneous coronary intervention (PCI).1 However, patients with CCS represent a heterogeneous population, and the type and duration of DAPT can be modulated weighting the individual ischemic and hemorrhagic risks. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 27, 2024 Category: Cardiology Authors: Giampaolo Niccoli, Filippo Luca Gurgoglione Tags: Editorial Source Type: research
PRECISE-DAPT, ARC-HBR or Simplified Clinical Evaluation for the Prediction of Major Bleeding after Percutaneous Coronary Intervention in Elderly Patients
Elderly patients have been remarkably under-represented in bleeding risk cohorts. Thus, the PRECISE-DAPT and ARC-HBR scores are not validated in older adults. Therefore, we sought to evaluate the PRECISE-DAPT and ARC-HBR scores in an exclusively elderly population and furthermore assess the prognostic value of a truly simplified clinical evaluation (SCE), consisting of only 3 binary clinical variables (hemoglobin (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 27, 2024 Category: Cardiology Authors: Alexander Marschall, Juan Duarte Torres, Bel én Biscotti Rodíl, Inés Gómez Sánchez, Elena Basabe Velasco, Carmen Ramos Alejos-Pita, Edurne López Soberón, Alfonso Suárez Cuervo, Salvador Álvarez Antón, Jose María de la Torre Hernández, David Ma Source Type: research
Association of Left Atrial Appendage Morphology and Function with Stroke and Transient Ischemic Attack in Atrial Fibrillation Patients
We aimed to correlate left atrial appendage (LAA) structure and function with the history of stroke/transient ischemic attack (TIA) in patients with atrial fibrillation (AF). We analyzed data of 649 patients with AF who were scheduled for catheter ablation. Patients underwent cardiac CT and transesophageal echocardiography prior to ablation. LAA morphologies depicted by cardiac CT were categorized into four groups: cauliflower, chicken wing, swan and windsock shapes. Mean age was 61.3 ±10.5 years, 33.9% were female. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 27, 2024 Category: Cardiology Authors: Judit Simon, Jeff M Smit, Mohammed El Mahdiui, Lili Sz áraz, Alexander R van Rosendael, Emese Zsarnóczay, Anikó Ilona Nagy, Lászlo Gellér, Rob J van der Geest, Jeroen J Bax, Pál Maurovich-Horvat, Béla Merkely Source Type: research
It's time to overcome the "One-Size-Fits-All" approach in chronic coronary syndrome?
Chronic coronary syndrome (CCS) refers to a wide spectrum of clinical conditions characterized by clinically stable progression of coronary artery disease (CAD) [1]. Current guidelines recommend the administration of dual antiplatelet therapy (DAPT) with cardioaspirin and clopidogrel for 6 months for patients undergoing elective percutaneous coronary intervention (PCI) [1]. However, patients with CCS represent a heterogeneous population and the type and duration of DAPT can be modulated weighting the individual ischemic and hemorrhagic risks [1]. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 27, 2024 Category: Cardiology Authors: Giampaolo Niccoli, Filippo Luca Gurgoglione Tags: Editorial Source Type: research
Lower Oral Anticoagulant Prescribing for Atrial Fibrillation in Women Compared With Men
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased risk of thromboembolic stroke.1 Stroke risk in AF varies greatly with age, gender, and co-morbidities. CHADS2VASc score2 is a commonly used to predict the annual risk of stroke and is calculated by adding 1 point each for the presence of congestive heart failure, hypertension, age>65 and (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 26, 2024 Category: Cardiology Authors: Veena Manja, Ciaran S. Phibbs, Ananth Lakshmi, Fay Saechao, Susan M. Frayne Tags: Brief Report Source Type: research
What Is True About False Tendons?
Left ventricular false tendons have been a bit of an enigma since they were first described by Turner in 18961. They are bands traversing the left ventricular cavity and arise embryologically from the same layer as trabeculations but are distinguished by being free in the LV cavity rather than being adherent to the wall. They can vary in orientation, thickness, and composition, being fibrous, muscular or a combination of both. They have been called by over a dozen names2 but the most common is left ventricular false tendon. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 26, 2024 Category: Cardiology Authors: David T. Linker Tags: Editorial Source Type: research
Aspirin for Primary Prevention in patients with Elevated Coronary Calcium Score: A systematic review of current evidences
The 2019 ACC/AHA guidelines regarding low-dose aspirin in primary prevention of Atherosclerotic Cardiovascular Disease (ASCVD) indicate increased risk of bleeding without a net benefit. Coronary Artery Calcium (CAC) score could be used to guide aspirin therapy in high-risk individuals without increased risk of bleeding. With this systematic review, we aim to analyse studies that have investigated the role of CAC in primary prevention with aspirin. Four relevant studies were identified and the primary outcomes of interest were bleeding events and major adverse cardiac events. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 26, 2024 Category: Cardiology Authors: Apoorva Doshi, Haresh Gandhi, Kunal N. Patel, Monil Majmundar, Rajkumar Doshi Source Type: research
Lower Oral Anticoagulant Prescribing for Atrial Fibrillation in Women compared to Men
Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased risk of thromboembolic stroke.1 Stroke risk in AF varies greatly with age, sex and comorbidities. CHADS2VASc score2 is a commonly used to predict the annual risk of stroke and is calculated by adding 1 point each for the presence of congestive heart failure, hypertension, age> 65 and (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 26, 2024 Category: Cardiology Authors: Veena Manja, Ciaran S. Phibbs, Ananth Lakshmi, Fay Saechao, Susan M. Frayne Tags: Brief report Source Type: research
Off-Pump Coronary Artery Bypass Grafting Does Not Confer Superior Outcomes Among Frail Patients
Coronary artery disease remains a leading cause of death in the United States, affecting nearly 20% of patients over 65 years of age.1 Advances in surgical technique and the development of reliable cardiopulmonary bypass strategies have allowed surgeons to safely and effectively perform coronary artery bypass grafting using cardiopulmonary bypass (ONCAB) with excellent outcomes. However, aortic manipulation, cardioplegic arrest, and extracorporeal circulation have been linked with complications in patients with reduced functional reserve. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 23, 2024 Category: Cardiology Authors: Sara Sakowitz, Syed Shahyan Bakhtiyar, Joanna Curry, Saad Mallick, Amulya Vadlakonda, Konmal Ali, Yas Sanaiha, Peyman Benharash Source Type: research
