No Penalty for Going Distal Radial
Transradial access (TRA) has become the dominant access site for coronary procedures over the past two decades1. Its ability to decrease access site complications and costs without a decrease in procedural success has led to an increase in adoption2. Fairly early in the process of adoption, patient comfort was found to be superior with radial access compared to femoral access3. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 18, 2024 Category: Cardiology Authors: Samir B. Pancholy, Tejas M. Patel Tags: Editorial Source Type: research

Clinical Protocol for Selecting Intracardiac or Transesophageal Echocardiography-Guided Left Atrial Appendage Occlusion
Left atrial appendage occlusion (LAAO) provides an effective alternative to oral anticoagulation (OAC) to reduce stroke risk in patients with nonvalvular atrial fibrillation (NVAF).1,2 Transesophageal echocardiography (TEE) has been the standard for LAAO guidance, but intracardiac echocardiography (ICE) use is increasing.3-5 Benefits of TEE include its familiarity to cardiologists, excellent image quality, and reproducibility.6 Conversely, ICE eliminates the need for general anesthesia with its associated complications and coordination while improving patient comfort. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 18, 2024 Category: Cardiology Authors: Kara Stout, Calvin Craig, Jaclyn Rivington, Elizabeth Lyden, Jason J. Payne, Andrew M. Goldsweig Source Type: research

The feasibility of left ventricular strain and strain rate for evaluating patients with risk factors of sudden cardiac death in hypertrophic cardiomyopathy by Feature-tracking Cardiac Magnetic Resonance
Sudden cardiac death (SCD) represents the most severe complication of hypertrophic cardiomyopathy (HCM). However, the relationship between strain, strain rate, and risk factors in SCD risk stratification remains elusive. The study aimed to assess the attenuation of strain and strain rate in HCM by feature-tracking cardiac magnetic resonance (FT-CMR). All strain and strain rates were obtained automatically by FT, with manual adjustment of endocardial and epicardial borders. Strain indicators included left ventricular (LV) global longitudinal (GLS), circumferential (GCS), radial strain (GRS), peak diastolic-longitudinal (PD-...
Source: The American Journal of Cardiology - April 18, 2024 Category: Cardiology Authors: Xinyu Zhu, Yuan Tian, Ying Shi, Jianxiu Lian, Honghu Shen, Lulu Li, Haishan Wu, Pengfei Liu Source Type: research

Association between chronic liver disease and adverse in-hospital outcomes in patients undergoing CABG: A propensity score-matched analysis of a 5-year national inpatient sample data from 2016-2020
This study investigates the association between CLD and in-hospital outcomes in CABG patients using retrospective data from the National Inpatient Sample (NIS) database (2016-2020) including 7,945 CLD patients undergoing CABG that were propensity score matched with an equivalent number of patients with no CLD undergoing CABG. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 18, 2024 Category: Cardiology Authors: Bekure B. Siraw, Parth Patel, Abdulrahim Y. Mehadi, Eli A. Zaher, Yordanos T. Tafesse Source Type: research

Trends In Percutaneous Device Use For The Treatment Of Venous Thromboembolism Over Time In The PINC AI Healthcare Database And The National Inpatient Sample
The number of different methodologies of reperfusion therapy to treat venous thromboembolism (VTE) has increased substantially. Nevertheless, investigation of data representativeness and device-level usage in administrative databases has been limited. Using the National Inpatient Sample (NIS) and the PINC AI Healthcare Database (PHD), all hospital encounters with a diagnosis code of VTE were identified between 1/1/2016 and 12/31/2020. Patient demographics and trends in treatment modalities were evaluated over time. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 17, 2024 Category: Cardiology Authors: Suzanne J. Baron, C. Michael Gibson, Ripal T. Gandhi, Derek Mittleider, David Dexter, Wissam A Jaber Source Type: research

Kidney and Cardiovascular Effectiveness of Empagliflozin Compared to Dipeptidyl Peptidase-4 Inhibitors in Patients with Type 2 Diabetes
Placebo-controlled trials of sodium-glucose cotransporter-2 inhibitors (SGLT2i) demonstrate kidney and cardiovascular benefits for people with type 2 diabetes (T2D) and chronic kidney disease (CKD). We used real-world data to compare the kidney and cardiovascular effectiveness of empagliflozin to dipeptidyl peptidase-4 inhibitors (DPP4i), a commonly prescribed antiglycemic medication, in a diverse population with and without CKD. Using electronic health record data from 20 large US health systems, we leveraged propensity overlap weighting to compare outcomes for empagliflozin and DPP4i initiators with T2D between 2016 and ...
Source: The American Journal of Cardiology - April 17, 2024 Category: Cardiology Authors: Daniel Edmonston, Hillary Mulder, Elizabeth Lydon, Karen Chiswell, Zachary Lampron, Christina Shay, Keith Marsolo, W. Schuyler Jones, Javed Butler, Raj C. Shah, Alanna M. Chamberlain, Daniel E. Ford, Howard S. Gordon, Wenke Hwang, Alexander Chang, Ajaykum Source Type: research

Transcatheter or Surgical Aortic Valve Replacement in Women with Small Annuli at Low or Intermediate Surgical Risk
While severe patient-prothesis mismatch (PPM) has been associated with increased mortality after surgical aortic valve replacement,1-3 the impact of PPM following transcatheter aortic valve replacement (TAVR) on hard clinical outcomes is still a matter of debate.4 In studies of PPM, particular attention has been paid to small aortic annuli, since it has been reported that these patients showed the greatest benefit of TAVR when compared to surgery, with significantly lower frequency of moderate and severe PPM post-procedure. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 17, 2024 Category: Cardiology Authors: Thomas Modine, John K. Forrest, Nicolas M. Van Mieghem, G. Michael Deeb, Steven J. Yakubov, Walid Ben Ali, Didier Tch étché, Ka Yan Lam, Jae K. Oh, Jian Huang, Roxana Mehran, Michael J. Reardon Source Type: research

Editorial Board
(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Source Type: research

Contents
(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Source Type: research

Prevalence and Predictors of Readmissions in Patients With Hypertrophic Cardiomyopathy and Atrial Fibrillation/Flutter
Atrial fibrillation/flutter (AF) is the most common dysrhythmia in patients with hypertrophic cardiomyopathy (HCM). Unexplained left ventricular hypertrophy and left ventricular outflow tract obstruction are integral components of HCM pathology which can cause increased left atrial pressure and atrial myopathy contributing to the substrate for AF. We aimed to determine the impact of AF on hospital readmissions in patients with HCM. We conducted a retrospective analysis using the 2015 to 2019 Nationwide Readmission Database to analyze the effect of AF on 30-day readmission and causes of 30-day readmission in patients with H...
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Muhammad Usman Almani, Khawaja Muhammad Talha, Laibah Arhsad Khan, Ishaque Hameed, Zain Ul Abideen Asad, Marat Fudim, Richard Krasuski, Muhammad Shahzeb Khan Source Type: research

Long-Term Outcomes of Bioprosthetic Valves in the Mitral Position: A Pooled Meta-Analysis of Reconstructed Time-to-Event Individual Patient Data
Bioprosthetic mitral valve replacement (bMVR) use is increasing; however, data regarding long-term durability are lacking. We sought to perform a reconstructed individual patient data meta-analysis from published Kaplan –Meier curves to ascertain survival, freedom from valve degeneration, and reoperation in studies published since 2010. We explored the effects of age and valve type (bovine pericardial or porcine valve) on outcomes. We searched MEDLINE, OVID, Embase, and Cochrane CENTRAL for studies reporting at l east 3 years of follow-up after bMVR and published since 2010. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Marinos Koulouroudias, Michele Di Mauro, Giovanni Chiariello, Paolo Meani, Roberto Lorusso Source Type: research

Improved Hemodynamics With Self-Expanding Compared to Balloon-Expandable Transcatheter Aortic Valve Implantation in Small Annulus Patients: A Propensity-Matched Analysis
This study aimed to compare the clinical and hemodynamic outcomes of self-expandable valve (SEV) versus balloon-expandable valve (BEV) transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis and SAAs. All patients who underwent TAVI for severe native aortic stenosis with an SAA between January 2018 and December 2022 were retrospectively included in the study from a single center. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Massimo Baudo, Serge Sicouri, Yoshiyuki Yamashita, Khalid Ridwan, Amer Kadri, Scott M. Goldman, Roberto Rodriguez, Eric M. Gnall, Paul M. Coady, Michael J. Reardon, Hemal Gada, William A. Gray, Basel Ramlawi Source Type: research

Prosthesis Infolding Incidence And Short-Term Outcomes In TAVI Using Evolut Self-Expandable Device: A Multicenter Study
Transcatheter aortic valve implantation (TAVI) is an established treatment strategy in aortic valve disease. Infolding, as a non-uniform expansion of the prosthesis leading to introflection of part of the device circumference, is a complication specific to self-expandable prostheses. The aim of the study is to determine incidence, predictors, treatment strategy and outcomes of infolding during Medtronic ™ Evolut TAVI. Between January 2018 and March 2022 all patients treated with Evolut TAVI were included in a multicenter observational retrospective study. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Andrea Bezzeccheri, Enrico Poletti, Paul Vermeersch, Verena Veulemans, Jarkko Piuhola, Seija Kerkel ä, Heidi Lehtola, Ole De Backer, Angelo Quagliana, Concetta Mammone, Flavio Ribichini, Edgard Prihadi, Benjamin Scott, Carlo Zivelonghi, Stefan Verheye, P Source Type: research

Improved Hemodynamics with Self-Expanding Compared to Balloon Expandable Transcatheter Aortic Valve Implantation in Small Annulus Patients: A Propensity-Matched Analysis
The objective of this study was to compare clinical and hemodynamic outcomes of self-expandable valves (SEV) versus balloon-expandable valves (BEV) transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis and SAA. All patients who underwent TAVI for severe native aortic stenosis with a SAA between January 2018 and December 2022 were retrospectively included in the study from a single center. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Massimo Baudo, Serge Sicouri, Yoshiyuki Yamashita, Khalid Ridwan, Amer Kadri, Scott M. Goldman, Roberto Rodriguez, Eric M. Gnall, Paul M. Coady, Michael J. Reardon, Hemal Gada, William A. Gray, Basel Ramlawi Source Type: research

GlycA Levels Independently Predict Coronary Artery Calcium Incidence and Progression in the ELSA-Brasil Cohort (Brazilian Longitudinal Study of Adult Health)
Atherosclerosis is an inflammatory disease. Coronary artery calcium (CAC) is a marker of atherosclerotic disease events and mortality risk. Elevated GlycA, an emerging marker of inflammation, is associated with a higher risk for coronary artery disease (CAD). However, there is conflicting evidence on whether GlycA predicts subclinical CAD progression. We hypothesized that GlycA can predict subclinical CAC incidence/progression in healthy individuals. We included 2,690 ELSA-Brasil cohort participants without cardiovascular/chronic inflammatory disease not receiving statin therapy who had GlycA levels measured and two interv...
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Ronaldo C. Fabiano Filho, Giuliano Generoso, Rhanderson Cardoso, Steven R. Jones, Raul D. Santos, Peter P. Toth, Isabela M Bensenor, Paulo A Lotufo, Marcio S. Bittencourt Source Type: research